Annotations: 3UJG

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3ujga_	Alpha and beta proteins (a+b)	Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	automated matches	automated matches	mouse-ear cress,thale-cress (Arabidopsis thaliana ) [TaxId: 3702 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	PP2C-like	8091304	3000909	SCOP2B (2022-06-29)
A	SCOP2 Family	Protein kinases catalytic domain-like	8062363	4003661	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Protein kinase-like (PK-like)	8062364	3000066	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PP2C	e3ujgB1	A: a+b four layers	X: Ntn/PP2C	H: Protein serine/threonine phosphatase 2C, catalytic domain (From Topology)	T: Protein serine/threonine phosphatase 2C, catalytic domain	F: PP2C	ECOD (1.6)
A	Pkinase_Tyr	e3ujgA2	A: a+b complex topology	X: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)	H: Protein kinase/SAICAR synthase/ATP-grasp	T: Protein kinase	F: Pkinase_Tyr	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.60.40.10	Alpha Beta	4-Layer Sandwich	Phosphatase 2c	domain 1	CATH (4.3.0)
A	3.30.200.20	Alpha Beta	2-Layer Sandwich	Phosphorylase Kinase	domain 1	CATH (4.3.0)
A	1.10.510.10	Mainly Alpha	Orthogonal Bundle	Transferase(Phosphotransferase)	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B	PF00481	Protein phosphatase 2C (PP2C)	Protein phosphatase 2C	-	Family
A	PF00069	Protein kinase domain (Pkinase)	Protein kinase domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B	Protein phosphatase 2C 16	phosphoric ester hydrolase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity catalytic activity, acting on a protein hydrolase activity, acting on ester bonds myosin phosphatase activity phosphatase activity hydrolase activity catalytic activity cation binding ion binding binding metal ion binding small molecule binding	cellular response to stimulus regulation of cellular process response to stimulus response to lipid abscisic acid-activated signaling pathway signaling hormone-mediated signaling pathway cell communication cellular response to endogenous stimulus response to hormone signal transduction cellular response to hormone stimulus cellular response to abscisic acid stimulus regulation of biological process cellular response to stimulus regulation of cellular process response to stimulus response to lipid abscisic acid-activated signaling pathway signaling hormone-mediated signaling pathway cell communication cellular response to endogenous stimulus response to hormone signal transduction cellular response to hormone stimulus cellular response to abscisic acid stimulus regulation of biological process response to abscisic acid response to alcohol response to endogenous stimulus biological regulation response to oxygen-containing compound cellular response to oxygen-containing compound cellular response to chemical stimulus cellular response to alcohol response to chemical cellular response to lipid cellular process	cellular anatomical structure intracellular anatomical structure cytoplasm membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle
A	Serine/threonine-protein kinase SRK2E	kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups protein serine/threonine kinase activity calcium-dependent protein serine/threonine kinase activity catalytic activity, acting on a protein protein kinase activity phosphotransferase activity, alcohol group as acceptor protein serine kinase activity protein phosphatase binding phosphatase binding protein binding binding kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups protein serine/threonine kinase activity calcium-dependent protein serine/threonine kinase activity catalytic activity, acting on a protein protein kinase activity phosphotransferase activity, alcohol group as acceptor protein serine kinase activity protein phosphatase binding phosphatase binding protein binding binding enzyme binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding identical protein binding	response to acid chemical response to stimulus response to stress response to chemical response to oxygen-containing compound response to abiotic stimulus response to water response to water deprivation cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to lipid abscisic acid-activated signaling pathway response to acid chemical response to stimulus response to stress response to chemical response to oxygen-containing compound response to abiotic stimulus response to water response to water deprivation cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to lipid abscisic acid-activated signaling pathway signaling positive regulation of biological process regulation of signal transduction hormone-mediated signaling pathway cell communication positive regulation of response to stimulus cellular response to endogenous stimulus response to hormone regulation of cellular response to alcohol signal transduction positive regulation of cellular process cellular response to hormone stimulus cellular response to abscisic acid stimulus regulation of biological process regulation of signaling regulation of response to alcohol response to abscisic acid response to alcohol response to endogenous stimulus biological regulation positive regulation of abscisic acid-activated signaling pathway cellular response to oxygen-containing compound cellular response to chemical stimulus cellular response to alcohol regulation of response to stimulus cellular response to lipid regulation of cell communication cellular process regulation of abscisic acid-activated signaling pathway positive regulation of signaling sucrose metabolic process carbohydrate metabolic process oligosaccharide metabolic process primary metabolic process metabolic process disaccharide metabolic process regulation of stomatal movement stomatal movement response to light stimulus response to light intensity cellular response to absence of light cellular response to light intensity cellular response to radiation response to absence of light cellular response to environmental stimulus cellular response to light stimulus response to radiation cellular response to abiotic stimulus fatty acid metabolic process unsaturated fatty acid metabolic process monocarboxylic acid biosynthetic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process lipid biosynthetic process organic acid biosynthetic process organic acid metabolic process fatty acid biosynthetic process carboxylic acid biosynthetic process unsaturated fatty acid biosynthetic process biosynthetic process small molecule metabolic process monocarboxylic acid metabolic process lipid metabolic process regulation of localization transport monoatomic ion transmembrane transport regulation of transmembrane transporter activity regulation of monoatomic ion transmembrane transport regulation of transporter activity localization regulation of monoatomic anion transport monoatomic anion transmembrane transport monoatomic ion transport regulation of monoatomic ion transmembrane transporter activity regulation of transport regulation of monoatomic ion transport regulation of monoatomic anion transmembrane transport regulation of anion channel activity establishment of localization transmembrane transport regulation of molecular function regulation of transmembrane transport monoatomic anion transport biological process involved in interspecies interaction between organisms response to other organism defense response response to external stimulus response to biotic stimulus defense response to bacterium defense response to other organism response to bacterium response to external biotic stimulus protein phosphorylation protein autophosphorylation phosphorylation macromolecule modification phosphate-containing compound metabolic process protein metabolic process macromolecule metabolic process protein modification process phosphorus metabolic process stomatal opening regulation of stomatal opening neutral lipid metabolic process neutral lipid biosynthetic process acylglycerol biosynthetic process glycerolipid biosynthetic process triglyceride metabolic process triglyceride biosynthetic process glycerolipid metabolic process acylglycerol metabolic process developmental process multicellular organism development multicellular organismal process plant organ development anatomical structure development leaf development shoot system development phyllome development system development stomatal closure regulation of stomatal closure reactive oxygen species metabolic process regulation of metabolic process regulation of reactive oxygen species metabolic process cellular response to carbon dioxide response to carbon dioxide response to osmotic stress response to salt stress	cell periphery cellular anatomical structure plasma membrane membrane intracellular anatomical structure cytoplasm membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B	IPR036457	PPM-type phosphatase-like domain superfamily	Homologous Superfamily
B	IPR015655	Protein phosphatase 2C	Family
B	IPR000222	PPM-type phosphatase, divalent cation binding	Binding Site
B	IPR001932	PPM-type phosphatase-like domain	Domain
A	IPR017441	Protein kinase, ATP binding site	Binding Site
A	IPR000719	Protein kinase domain	Domain
A	IPR011009	Protein kinase-like domain superfamily	Homologous Superfamily
A	IPR008271	Serine/threonine-protein kinase, active site	Active Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.