Annotations: 3UJK

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	PP2C-like	8091301	4007727	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	PP2C-like	8091302	3000909	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PP2C	e3ujkA1	A: a+b four layers	X: Ntn/PP2C	H: Protein serine/threonine phosphatase 2C, catalytic domain (From Topology)	T: Protein serine/threonine phosphatase 2C, catalytic domain	F: PP2C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.60.40.10	Alpha Beta	4-Layer Sandwich	Phosphatase 2c	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00481	Protein phosphatase 2C (PP2C)	Protein phosphatase 2C	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Protein phosphatase 2C 77	phosphoric ester hydrolase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity catalytic activity, acting on a protein hydrolase activity, acting on ester bonds myosin phosphatase activity phosphatase activity hydrolase activity catalytic activity cation binding ion binding binding metal ion binding small molecule binding	response to acid chemical response to stimulus response to stress response to chemical response to oxygen-containing compound response to abiotic stimulus response to water response to water deprivation regulation of cellular process regulation of protein modification process regulation of catalytic activity regulation of protein phosphorylation negative regulation of biological process negative regulation of phosphate metabolic process response to acid chemical response to stimulus response to stress response to chemical response to oxygen-containing compound response to abiotic stimulus response to water response to water deprivation regulation of cellular process regulation of protein modification process regulation of catalytic activity regulation of protein phosphorylation negative regulation of biological process negative regulation of phosphate metabolic process negative regulation of catalytic activity regulation of transferase activity regulation of primary metabolic process negative regulation of kinase activity negative regulation of transferase activity regulation of phosphate metabolic process phosphate-containing compound metabolic process negative regulation of protein modification process negative regulation of cellular process protein metabolic process phosphorus metabolic process protein modification process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biological process protein phosphorylation phosphorylation regulation of protein metabolic process negative regulation of metabolic process biological regulation negative regulation of molecular function primary metabolic process negative regulation of protein kinase activity regulation of protein kinase activity regulation of macromolecule metabolic process regulation of molecular function regulation of kinase activity negative regulation of protein phosphorylation macromolecule modification negative regulation of phosphorus metabolic process regulation of phosphorylation regulation of phosphorus metabolic process cellular process metabolic process macromolecule metabolic process negative regulation of phosphorylation regulation of metabolic process cellular response to stimulus response to lipid abscisic acid-activated signaling pathway signaling hormone-mediated signaling pathway cell communication cellular response to endogenous stimulus response to hormone signal transduction cellular response to hormone stimulus cellular response to abscisic acid stimulus response to abscisic acid response to alcohol response to endogenous stimulus cellular response to oxygen-containing compound cellular response to chemical stimulus cellular response to alcohol cellular response to lipid response to light stimulus photosynthesis negative regulation of photosynthesis, light reaction regulation of photosynthesis, light reaction photosynthetic electron transport chain electron transport chain regulation of generation of precursor metabolites and energy response to high light intensity photoinhibition response to light intensity regulation of photosynthesis photosynthesis, light reaction generation of precursor metabolites and energy response to radiation negative regulation of photosynthesis response to heat response to temperature stimulus response to osmotic stress regulation of stomatal movement stomatal opening stomatal movement regulation of stomatal opening	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR036457	PPM-type phosphatase-like domain superfamily	Homologous Superfamily
A	IPR015655	Protein phosphatase 2C	Family
A	IPR000222	PPM-type phosphatase, divalent cation binding	Binding Site
A	IPR001932	PPM-type phosphatase-like domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.