Annotations: 4N8K

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	AcetylCoA_hyd_C	e4n8kB2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: AcetylCoA_hyd_C	ECOD (1.6)
B	CoA_trans	e4n8kB1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: CoA_trans	ECOD (1.6)
A	AcetylCoA_hyd_C	e4n8kA2	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: AcetylCoA_hyd_C	ECOD (1.6)
A	CoA_trans	e4n8kA1	A: a/b three-layered sandwiches	X: Rossmann-like	H: Rossmann-related	T: NagB/RpiA/CoA transferase-like	F: CoA_trans	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF02550	Acetyl-CoA hydrolase/transferase N-terminal domain (AcetylCoA_hydro)	Acetyl-CoA hydrolase/transferase N-terminal domain	This family contains several enzymes which take part in pathways involving acetyl-CoA. Acetyl-CoA hydrolase EC:3.1.2.1 (Swiss:P32316) catalyses the formation of acetate from acetyl-CoA, CoA transferase (CAT1) EC:2.8.3.- (Swiss:P38946) produces succin ...	This family contains several enzymes which take part in pathways involving acetyl-CoA. Acetyl-CoA hydrolase EC:3.1.2.1 (Swiss:P32316) catalyses the formation of acetate from acetyl-CoA, CoA transferase (CAT1) EC:2.8.3.- (Swiss:P38946) produces succinyl-CoA, and acetate-CoA transferase EC:2.8.3.8 (Swiss:Q59323) utilises acyl-CoA and acetate to form acetyl-CoA.	Domain
A, B	PF13336	Acetyl-CoA hydrolase/transferase C-terminal domain (AcetylCoA_hyd_C)	Acetyl-CoA hydrolase/transferase C-terminal domain	This family contains several enzymes which take part in pathways involving acetyl-CoA. Acetyl-CoA hydrolase EC:3.1.2.1 (Swiss:P32316) catalyses the formation of acetate from acetyl-CoA, CoA transferase (CAT1) EC:2.8.3.- (Swiss:P38946) produces succin ...	This family contains several enzymes which take part in pathways involving acetyl-CoA. Acetyl-CoA hydrolase EC:3.1.2.1 (Swiss:P32316) catalyses the formation of acetate from acetyl-CoA, CoA transferase (CAT1) EC:2.8.3.- (Swiss:P38946) produces succinyl-CoA, and acetate-CoA transferase EC:2.8.3.8 (Swiss:Q59323) utilises acyl-CoA and acetate to form acetyl-CoA.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Putative 4-hydroxybutyrate coenzyme A transferase	acetate CoA-transferase activity transferase activity, transferring sulphur-containing groups transferase activity catalytic activity CoA-transferase activity	oxoacid metabolic process carboxylic acid metabolic process acetate metabolic process small molecule metabolic process metabolic process cellular process monocarboxylic acid metabolic process organic acid metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR026888	Acetyl-CoA hydrolase/transferase, C-terminal domain	Domain
A, B	IPR046433	Acetyl-CoA hydrolase/transferase	Family
A, B	IPR037171	NagB/RpiA transferase-like	Homologous Superfamily
A, B	IPR003702	Acetyl-CoA hydrolase/transferase, N-terminal	Domain
A, B	IPR038460	Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.