4LKD

Crystal Structure of Pseudomonas aeruginosa Lectin LecA Complexed with GalA-QRS at 2.31 A Resolution

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	galactose-binding domain-like	8042929	3000087	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PA-IL	e4lkdB1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
C	PA-IL	e4lkdC1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
D	PA-IL	e4lkdD1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
E	PA-IL	e4lkdE1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
G	PA-IL	e4lkdG1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
H	PA-IL	e4lkdH1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
A	PA-IL	e4lkdA1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)
F	PA-IL	e4lkdF1	A: beta sandwiches	X: jelly-roll	H: Concanavalin A-like	T: Galactose-binding domain-like	F: PA-IL	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
C	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
D	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
E	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
G	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
H	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
A	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)
F	2.60.120.430	Mainly Beta	Sandwich	Jelly Rolls	Galactose-binding lectin	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF07828	PA-IL-like protein (PA-IL)	PA-IL-like protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	PA-I galactophilic lectin	binding carbohydrate binding	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules cell adhesion cell-cell adhesion cellular process cell-cell adhesion via plasma-membrane adhesion molecules	cell surface cellular anatomical structure periplasmic space intracellular anatomical structure cytoplasm
I, J, K, L, M I, J, K, L, M, N, O, P	peptide QRSA	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR012905	PA-IL-like	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR008979	Galactose-binding-like domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.