Annotations: 5HWJ

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
D	d5hwjd1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Aldolase	automated matches	automated matches	(Agrobacterium fabrum str. C58 ) [TaxId: 176299 ],	SCOPe (2.08)
D	d5hwjd2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Agrobacterium fabrum str. C58 ) [TaxId: 176299 ],	SCOPe (2.08)
A	d5hwja1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Aldolase	automated matches	automated matches	(Agrobacterium fabrum str. C58 ) [TaxId: 176299 ],	SCOPe (2.08)
A	d5hwja2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Agrobacterium fabrum str. C58 ) [TaxId: 176299 ],	SCOPe (2.08)
B	d5hwjb_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Aldolase	automated matches	automated matches	(Agrobacterium fabrum str. C58 ) [TaxId: 176299 ],	SCOPe (2.08)
C	d5hwjc_	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	Aldolase	automated matches	automated matches	(Agrobacterium fabrum str. C58 ) [TaxId: 176299 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
D	DHDPS	e5hwjD1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: DHDPS	ECOD (1.6)
A	DHDPS	e5hwjA1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: DHDPS	ECOD (1.6)
B	DHDPS	e5hwjB1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: DHDPS	ECOD (1.6)
C	DHDPS	e5hwjC1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: DHDPS	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
D	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
A	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
B	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
C	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00701	Dihydrodipicolinate synthetase family (DHDPS)	Dihydrodipicolinate synthetase family	This family has a TIM barrel structure.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Probable 5-dehydro-4-deoxyglucarate dehydratase	4-hydroxy-tetrahydrodipicolinate synthase activity hydro-lyase activity lyase activity catalytic activity carbon-oxygen lyase activity 5-dehydro-4-deoxyglucarate dehydratase activity	carbohydrate metabolic process D-glucarate catabolic process catabolic process oxoacid metabolic process glucarate metabolic process dicarboxylic acid metabolic process carbohydrate catabolic process carboxylic acid metabolic process primary metabolic process glucarate catabolic process organic acid metabolic process dicarboxylic acid catabolic process organic acid catabolic process aldaric acid metabolic process cellular catabolic process carbohydrate metabolic process D-glucarate catabolic process catabolic process oxoacid metabolic process glucarate metabolic process dicarboxylic acid metabolic process carbohydrate catabolic process carboxylic acid metabolic process primary metabolic process glucarate catabolic process organic acid metabolic process dicarboxylic acid catabolic process organic acid catabolic process aldaric acid metabolic process cellular catabolic process aldaric acid catabolic process carboxylic acid catabolic process D-glucarate metabolic process metabolic process cellular process small molecule metabolic process small molecule catabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR013785	Aldolase-type TIM barrel	Homologous Superfamily
A, B, C, D	IPR017655	5-dehydro-4-deoxyglucarate dehydratase	Family
A, B, C, D	IPR002220	DapA-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.