Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad5ni4a3 All alpha proteins alpha-alpha superhelix ARM repeat Leukotriene A4 hydrolase C-terminal domain Leukotriene A4 hydrolase C-terminal domain Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad5ni4a1 All beta proteins Zn aminopeptidase N-terminal domain Zn aminopeptidase N-terminal domain Zn aminopeptidase N-terminal domain Leukotriene A4 hydrolase N-terminal domain Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Ad5ni4a2 Alpha and beta proteins (a+b) Zincin-like Metalloproteases ('zincins'), catalytic domain Zn aminopeptidase catalytic domain Leukotriene A4 hydrolase catalytic domain Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd5ni4c3 All alpha proteins alpha-alpha superhelix ARM repeat Leukotriene A4 hydrolase C-terminal domain Leukotriene A4 hydrolase C-terminal domain Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd5ni4c1 All beta proteins Zn aminopeptidase N-terminal domain Zn aminopeptidase N-terminal domain Zn aminopeptidase N-terminal domain Leukotriene A4 hydrolase N-terminal domain Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Cd5ni4c2 Alpha and beta proteins (a+b) Zincin-like Metalloproteases ('zincins'), catalytic domain Zn aminopeptidase catalytic domain Leukotriene A4 hydrolase catalytic domain Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd5ni4b3 All alpha proteins alpha-alpha superhelix ARM repeat Leukotriene A4 hydrolase C-terminal domain Leukotriene A4 hydrolase C-terminal domain Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd5ni4b1 All beta proteins Zn aminopeptidase N-terminal domain Zn aminopeptidase N-terminal domain Zn aminopeptidase N-terminal domain Leukotriene A4 hydrolase N-terminal domain Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Bd5ni4b2 Alpha and beta proteins (a+b) Zincin-like Metalloproteases ('zincins'), catalytic domain Zn aminopeptidase catalytic domain Leukotriene A4 hydrolase catalytic domain Human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyLeukotriene A4 hydrolase N-terminal domain 8038930 3000390 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyARM repeat-like 8038928 3000116 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMetalloproteases (zincins), catalytic domain 8038934 3001975 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyLeukotriene A4 hydrolase N-terminal domain 8038930 3000390 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyMetalloproteases (zincins), catalytic domain 8038934 3001975 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyARM repeat-like 8038928 3000116 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyARM repeat-like 8038928 3000116 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyLeukotriene A4 hydrolase N-terminal domain 8038930 3000390 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyMetalloproteases (zincins), catalytic domain 8038934 3001975 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APeptidase_M1_2e5ni4A2 A: beta sandwichesX: Baculovirus p35 protein-related (From Topology)H: Baculovirus p35 protein-related (From Topology)T: Baculovirus p35 protein-relatedF: Peptidase_M1_2ECOD (1.6)
ALeuk-A4-hydro_Ce5ni4A3 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: Leuk-A4-hydro_CECOD (1.6)
APeptidase_M1_1e5ni4A1 A: mixed a+b and a/bX: Zincin-likeH: Metalloproteases (zincins) catalytic domain (From Topology)T: Metalloproteases (zincins) catalytic domainF: Peptidase_M1_1ECOD (1.6)
CPeptidase_M1_2e5ni4C3 A: beta sandwichesX: Baculovirus p35 protein-related (From Topology)H: Baculovirus p35 protein-related (From Topology)T: Baculovirus p35 protein-relatedF: Peptidase_M1_2ECOD (1.6)
CLeuk-A4-hydro_Ce5ni4C2 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: Leuk-A4-hydro_CECOD (1.6)
CPeptidase_M1_1e5ni4C1 A: mixed a+b and a/bX: Zincin-likeH: Metalloproteases (zincins) catalytic domain (From Topology)T: Metalloproteases (zincins) catalytic domainF: Peptidase_M1_1ECOD (1.6)
BPeptidase_M1_2e5ni4B1 A: beta sandwichesX: Baculovirus p35 protein-related (From Topology)H: Baculovirus p35 protein-related (From Topology)T: Baculovirus p35 protein-relatedF: Peptidase_M1_2ECOD (1.6)
BLeuk-A4-hydro_Ce5ni4B2 A: alpha superhelicesX: Repetitive alpha hairpinsH: ARM repeat (From Topology)T: ARM repeatF: Leuk-A4-hydro_CECOD (1.6)
BPeptidase_M1_1e5ni4B3 A: mixed a+b and a/bX: Zincin-likeH: Metalloproteases (zincins) catalytic domain (From Topology)T: Metalloproteases (zincins) catalytic domainF: Peptidase_M1_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C
PF09127Leukotriene A4 hydrolase, C-terminal (Leuk-A4-hydro_C)Leukotriene A4 hydrolase, C-terminal- Repeat
A, B, C
PF01433Peptidase family M1 domain (Peptidase_M1)Peptidase family M1 domainMembers of this family are aminopeptidases. The members differ widely in specificity, hydrolysing acidic, basic or neutral N-terminal residues. This family includes leukotriene-A4 hydrolase Swiss:P09960, this enzyme also has an aminopeptidase activ ...Members of this family are aminopeptidases. The members differ widely in specificity, hydrolysing acidic, basic or neutral N-terminal residues. This family includes leukotriene-A4 hydrolase Swiss:P09960, this enzyme also has an aminopeptidase activity [1].
Domain
A, B, C
PF17900Peptidase M1 N-terminal domain (Peptidase_M1_N)Peptidase M1 N-terminal domainThis domain is found at the N-terminus of aminopeptidases from the M1 family.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C
Leukotriene A-4 hydrolase