6FCR

The X-ray Structure of Lytic Transglycosylase Slt inactive mutant E503Q from Pseudomonas aeruginosa in complex with NAG-NAMtetrapeptide-NAG-anhNAMtetrapeptide

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	SLT_L	e6fcrA2	A: alpha superhelices	X: Repetitive alpha hairpins	H: ARM repeat (From Topology)	T: ARM repeat	F: SLT_L	ECOD (1.6)
A	SLT	e6fcrA1	A: a+b complex topology	X: Lysozyme-like (From Homology)	H: Lysozyme-like	T: Lysozyme-like	F: SLT	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF14718	Soluble lytic murein transglycosylase L domain (SLT_L)	Soluble lytic murein transglycosylase L domain	-	Repeat
A	PF01464	Transglycosylase SLT domain (SLT)	Transglycosylase SLT domain	This family is distantly related to Pfam:PF00062. Members are found in phages, type II, type III and type IV secretion systems (reviewed in [4]).	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B [auth F], C [auth G]	ALA-DGL-API-DAL	-	-	-
A	Soluble lytic murein transglycosylase	hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity	-	cellular anatomical structure periplasmic space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR037061	Lytic transglycosylase, superhelical linker domain superfamily	Homologous Superfamily
A	IPR008939	Lytic transglycosylase, superhelical U-shaped	Homologous Superfamily
A	IPR012289	Lytic transglycosylase, superhelical linker	Domain
A	IPR023346	Lysozyme-like domain superfamily	Homologous Superfamily
A	IPR008258	Transglycosylase SLT domain 1	Domain

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
B [auth F], C [auth G]	API	Parent Component: LYS
B [auth F], C [auth G]	DAL	RESID: AA0111 , AA0191 PSI-MOD : meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862
B [auth F], C [auth G]	DGL	RESID: AA0111 , AA0191

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.