8XP2

Cryo-EM structure of the human 40S ribosome with LARP1

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Pharos: Disease Associations

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth Ln]	60S ribosomal protein L41	mRNA 3'-UTR binding RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding mRNA 5'-UTR binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol protein-containing complex intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cellular anatomical structure intracellular anatomical structure cytoplasm cytosol protein-containing complex intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome large ribosomal subunit membrane-bounded organelle endoplasmic reticulum intracellular membrane-bounded organelle endomembrane system
B [auth S2]	18S rRNA	-	-	-
C [auth SA]	40S ribosomal protein SA	protein binding binding virus receptor activity exogenous protein binding RNA binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome extracellular matrix binding laminin binding cell adhesion molecule binding laminin receptor activity cell adhesion mediator activity protein binding binding virus receptor activity exogenous protein binding RNA binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome extracellular matrix binding laminin binding cell adhesion molecule binding laminin receptor activity cell adhesion mediator activity DNA binding ribonucleoprotein complex binding protein-containing complex binding ribosome binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process biological process involved in interspecies interaction between organisms response to stimulus immune response response to other organism biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process biological process involved in interspecies interaction between organisms response to stimulus immune response response to other organism defense response defense response to symbiont response to external stimulus response to biotic stimulus defense response to virus immune system process defense response to other organism response to stress innate immune response antiviral innate immune response response to external biotic stimulus response to virus ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly ribosomal small subunit biogenesis cellular component organization cellular component biogenesis ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly cellular component organization or biogenesis ribosome assembly	cellular anatomical structure membrane extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle intracellular anatomical structure cytoplasm cytosol cellular anatomical structure membrane extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle intracellular anatomical structure cytoplasm cytosol cell periphery plasma membrane nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle nucleoplasm organelle lumen nuclear lumen cytosolic ribosome membraneless organelle intracellular membraneless organelle ribosome cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex
D [auth SB]	40S ribosomal protein S3a	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome mRNA 5'-UTR binding mRNA binding	biosynthetic process translational initiation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process developmental process cellular developmental process cell differentiation regulation of biological process biosynthetic process translational initiation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process developmental process cellular developmental process cell differentiation regulation of biological process regulation of cellular process negative regulation of programmed cell death regulation of apoptotic process biological regulation negative regulation of biological process regulation of programmed cell death cell death negative regulation of apoptotic process negative regulation of cellular process apoptotic process programmed cell death cytoplasmic translation cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle cytoplasm cytosol nucleoplasm cytosolic ribosome ribosome preribosome protein-containing complex ribonucleoprotein complex small-subunit processome synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit endoplasmic reticulum endomembrane system
E [auth SD]	40S ribosomal protein S3	DNA binding oxidized DNA binding oxidized pyrimidine DNA binding binding organic cyclic compound binding damaged DNA binding nucleic acid binding structural molecule activity structural constituent of ribosome ubiquitin-like protein conjugating enzyme binding protein binding enzyme binding cytoskeletal protein binding microtubule binding DNA binding oxidized DNA binding oxidized pyrimidine DNA binding binding organic cyclic compound binding damaged DNA binding nucleic acid binding structural molecule activity structural constituent of ribosome ubiquitin-like protein conjugating enzyme binding protein binding enzyme binding cytoskeletal protein binding microtubule binding tubulin binding RNA binding mRNA binding double-stranded DNA binding supercoiled DNA binding protein-containing complex binding DNA-(apurinic or apyrimidinic site) endonuclease activity catalytic activity, acting on DNA catalytic activity, acting on a nucleic acid class I DNA-(apurinic or apyrimidinic site) endonuclease activity lyase activity catalytic activity carbon-oxygen lyase activity oxidized purine DNA binding small ribosomal subunit rRNA binding rRNA binding protein kinase A binding iron-sulfur cluster binding metal cluster binding small molecule binding Hsp90 protein binding heat shock protein binding DNA endonuclease activity endonuclease activity nuclease activity hydrolase activity, acting on ester bonds hydrolase activity DNA nuclease activity Hsp70 protein binding protein-folding chaperone binding kinase binding protein kinase binding transcription factor binding DNA-binding transcription factor binding	cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process biosynthetic process translational initiation metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process biosynthetic process translational initiation metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process positive regulation of cell communication regulation of cellular process positive regulation of signal transduction signaling positive regulation of biological process regulation of cellular response to stress regulation of signal transduction regulation of intrinsic apoptotic signaling pathway in response to DNA damage regulation of programmed cell death regulation of intrinsic apoptotic signaling pathway intracellular signal transduction cell communication positive regulation of apoptotic signaling pathway positive regulation of response to stimulus regulation of intracellular signal transduction regulation of response to stress intrinsic apoptotic signaling pathway in response to DNA damage signal transduction intrinsic apoptotic signaling pathway positive regulation of cellular process regulation of biological process regulation of signaling positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage positive regulation of programmed cell death regulation of apoptotic process biological regulation positive regulation of intracellular signal transduction cell death positive regulation of apoptotic process apoptotic signaling pathway regulation of response to stimulus regulation of cell communication positive regulation of intrinsic apoptotic signaling pathway apoptotic process programmed cell death regulation of apoptotic signaling pathway positive regulation of signaling regulation of primary metabolic process nucleobase-containing compound metabolic process regulation of base-excision repair positive regulation of metabolic process positive regulation of DNA repair base-excision repair positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process DNA repair positive regulation of nucleobase-containing compound metabolic process DNA metabolic process regulation of macromolecule metabolic process nucleic acid metabolic process regulation of DNA repair positive regulation of DNA metabolic process positive regulation of base-excision repair regulation of metabolic process regulation of DNA metabolic process cell division negative regulation of post-translational protein modification regulation of protein modification process negative regulation of biological process regulation of protein ubiquitination protein ubiquitination negative regulation of protein modification process negative regulation of cellular process negative regulation of protein ubiquitination regulation of protein modification by small protein conjugation or removal protein modification process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process negative regulation of protein modification by small protein conjugation or removal regulation of post-translational protein modification regulation of protein metabolic process negative regulation of metabolic process macromolecule modification post-translational protein modification protein modification by small protein conjugation protein modification by small protein conjugation or removal regulation of biosynthetic process positive regulation of macromolecule biosynthetic process regulation of gene expression positive regulation of gene expression positive regulation of biosynthetic process regulation of macromolecule biosynthetic process cell cycle chromosome segregation cell cycle process positive regulation of cellular component organization regulation of cellular component organization protein-containing complex organization positive regulation of cellular component biogenesis regulation of cellular component biogenesis cellular component organization cellular component biogenesis positive regulation of protein-containing complex assembly regulation of protein-containing complex assembly cellular component assembly protein-containing complex assembly cellular component organization or biogenesis response to chemical response to TNF agonist immune response-regulating cell surface receptor signaling pathway positive regulation of T cell receptor signaling pathway regulation of antigen receptor-mediated signaling pathway immune response-activating signaling pathway immune response-regulating signaling pathway positive regulation of immune response regulation of immune system process positive regulation of immune system process cell surface receptor signaling pathway immune response-activating cell surface receptor signaling pathway immune response regulation of T cell receptor signaling pathway T cell receptor signaling pathway immune system process regulation of immune response antigen receptor-mediated signaling pathway activation of immune response positive regulation of antigen receptor-mediated signaling pathway positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity RNA metabolic process RNA biosynthetic process positive regulation of molecular function nucleic acid biosynthetic process DNA-templated transcription regulation of RNA metabolic process regulation of RNA biosynthetic process nucleobase-containing compound biosynthetic process regulation of molecular function regulation of DNA-binding transcription factor activity regulation of DNA-templated transcription positive regulation of organelle organization regulation of cytoskeleton organization regulation of microtubule polymerization or depolymerization microtubule cytoskeleton organization microtubule polymerization or depolymerization positive regulation of protein polymerization protein polymerization positive regulation of microtubule polymerization or depolymerization positive regulation of cytoskeleton organization regulation of microtubule-based process microtubule polymerization positive regulation of supramolecular fiber organization regulation of organelle organization organelle organization positive regulation of microtubule polymerization regulation of protein polymerization regulation of microtubule polymerization regulation of supramolecular fiber organization microtubule-based process supramolecular fiber organization cytoskeleton organization regulation of microtubule cytoskeleton organization positive regulation of phosphorylation regulation of catalytic activity regulation of transferase activity positive regulation of phosphate metabolic process regulation of MAP kinase activity positive regulation of protein serine/threonine kinase activity regulation of phosphate metabolic process phosphate-containing compound metabolic process intracellular signaling cassette phosphorus metabolic process positive regulation of protein phosphorylation positive regulation of MAP kinase activity protein phosphorylation positive regulation of phosphorus metabolic process phosphorylation positive regulation of MAPK cascade positive regulation of JUN kinase activity regulation of MAPK cascade positive regulation of kinase activity regulation of kinase activity regulation of protein serine/threonine kinase activity regulation of phosphorus metabolic process regulation of protein phosphorylation positive regulation of protein metabolic process positive regulation of protein modification process positive regulation of protein kinase activity positive regulation of transferase activity positive regulation of catalytic activity regulation of protein kinase activity regulation of JUN kinase activity MAPK cascade regulation of phosphorylation post-transcriptional regulation of gene expression negative regulation of translation negative regulation of gene expression negative regulation of biosynthetic process regulation of translation negative regulation of macromolecule biosynthetic process negative regulation of DNA repair negative regulation of nucleobase-containing compound metabolic process negative regulation of response to stimulus negative regulation of DNA metabolic process organelle assembly membraneless organelle assembly spindle assembly spindle organization regulation of endodeoxyribonuclease activity regulation of deoxyribonuclease activity regulation of nuclease activity positive regulation of endodeoxyribonuclease activity positive regulation of deoxyribonuclease activity positive regulation of nuclease activity positive regulation of hydrolase activity regulation of hydrolase activity cellular response to oxidative stress response to oxygen-containing compound cellular response to chemical stress cellular response to oxygen-containing compound cellular response to hydrogen peroxide response to reactive oxygen species response to hydrogen peroxide response to oxidative stress cellular response to reactive oxygen species cellular response to chemical stimulus response to peptide cellular response to tumor necrosis factor response to cytokine cellular response to cytokine stimulus response to tumor necrosis factor multicellular organismal process positive regulation of cell population proliferation regulation of leukocyte activation regulation of cell activation positive regulation of cell activation T cell activation lymphocyte proliferation positive regulation of leukocyte activation regulation of leukocyte proliferation cell population proliferation positive regulation of T cell activation positive regulation of lymphocyte proliferation positive regulation of T cell proliferation positive regulation of activated T cell proliferation regulation of cell population proliferation mononuclear cell proliferation regulation of leukocyte cell-cell adhesion positive regulation of leukocyte proliferation positive regulation of multicellular organismal process regulation of activated T cell proliferation positive regulation of leukocyte cell-cell adhesion lymphocyte activation leukocyte proliferation leukocyte cell-cell adhesion leukocyte activation activated T cell proliferation positive regulation of cell-cell adhesion positive regulation of lymphocyte activation cell adhesion cell-cell adhesion positive regulation of mononuclear cell proliferation regulation of multicellular organismal process regulation of cell-cell adhesion T cell proliferation regulation of lymphocyte proliferation positive regulation of cell adhesion regulation of cell adhesion cell activation regulation of T cell activation regulation of T cell proliferation regulation of mononuclear cell proliferation regulation of lymphocyte activation cytoplasmic translation regulation of cytokine production cytokine production regulation of interleukin-2 production interleukin-2 production positive regulation of interleukin-2 production positive regulation of cytokine production regulation of non-canonical NF-kappaB signal transduction non-canonical NF-kappaB signal transduction positive regulation of non-canonical NF-kappaB signal transduction	cellular anatomical structure membrane extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle intracellular anatomical structure cytoplasm cytosol cellular anatomical structure membrane extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle intracellular anatomical structure cytoplasm cytosol intracellular organelle protein-containing complex NF-kappaB complex nucleus nuclear protein-containing complex intracellular membrane-bounded organelle mitochondrial membrane organelle inner membrane mitochondrion mitochondrial inner membrane organelle envelope mitochondrial envelope organelle membrane anchoring junction cell junction focal adhesion cell-substrate junction membrane-enclosed lumen intracellular membraneless organelle nucleolus intracellular organelle lumen organelle lumen membraneless organelle nuclear lumen ruffle cell leading edge plasma membrane leading edge membrane plasma membrane bounded cell projection cell periphery cell projection ruffle membrane plasma membrane region cell projection membrane mitotic spindle cytoskeleton spindle microtubule cytoskeleton nucleoplasm ribosome cytosolic ribosome postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization synapse asymmetric synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit ribonucleoprotein complex mitochondrial matrix endoplasmic reticulum endomembrane system
F [auth SE]	40S ribosomal protein S4, X isoform	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	regulation of biological process cell population proliferation regulation of cellular process positive regulation of cell population proliferation regulation of cell population proliferation biological regulation positive regulation of biological process cellular process positive regulation of cellular process positive regulation of protein metabolic process positive regulation of translation positive regulation of macromolecule biosynthetic process regulation of primary metabolic process post-transcriptional regulation of gene expression regulation of biological process cell population proliferation regulation of cellular process positive regulation of cell population proliferation regulation of cell population proliferation biological regulation positive regulation of biological process cellular process positive regulation of cellular process positive regulation of protein metabolic process positive regulation of translation positive regulation of macromolecule biosynthetic process regulation of primary metabolic process post-transcriptional regulation of gene expression positive regulation of metabolic process positive regulation of biosynthetic process positive regulation of macromolecule metabolic process protein metabolic process regulation of biosynthetic process regulation of protein metabolic process primary metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process regulation of gene expression biosynthetic process positive regulation of gene expression regulation of translation regulation of macromolecule biosynthetic process metabolic process macromolecule metabolic process regulation of metabolic process cytoplasmic translation cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle cytoplasm cytosol nucleoplasm ribosome cytoplasmic ribonucleoprotein granule supramolecular complex ribonucleoprotein granule protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex cytosolic ribosome preribosome small-subunit processome synapse cytosolic small ribosomal subunit
G [auth SF]	40S ribosomal protein S5	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome mRNA binding	biosynthetic process translational initiation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process biological regulation regulation of biological quality regulation of translational fidelity cytoplasmic translation biosynthetic process translational initiation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process biological regulation regulation of biological quality regulation of translational fidelity cytoplasmic translation cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly cellular component organization organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly ribosome assembly	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle cytoplasm cytosol nucleoplasm ribosome cytosolic ribosome preribosome protein-containing complex ribonucleoprotein complex small-subunit processome synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit
H [auth SH]	40S ribosomal protein S7	mRNA 3'-UTR binding RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome protein binding kinase binding enzyme binding protein kinase binding enzyme regulator activity molecular function inhibitor activity mRNA 3'-UTR binding RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome protein binding kinase binding enzyme binding protein kinase binding enzyme regulator activity molecular function inhibitor activity ubiquitin-protein transferase regulator activity ubiquitin-protein transferase inhibitor activity ubiquitin ligase inhibitor activity molecular function regulator activity enzyme inhibitor activity mRNA 5'-UTR binding	regulation of protein stability biological regulation regulation of biological quality protein stabilization developmental process neural crest cell differentiation cellular developmental process animal organ development mesenchyme development tissue development stem cell differentiation cell differentiation anatomical structure development cellular process regulation of protein stability biological regulation regulation of biological quality protein stabilization developmental process neural crest cell differentiation cellular developmental process animal organ development mesenchyme development tissue development stem cell differentiation cell differentiation anatomical structure development cellular process mesenchymal cell differentiation regulation of biosynthetic process regulation of biological process regulation of cellular process positive regulation of biological process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process positive regulation of macromolecule biosynthetic process regulation of gene expression positive regulation of metabolic process biosynthetic process positive regulation of gene expression positive regulation of biosynthetic process regulation of macromolecule biosynthetic process metabolic process positive regulation of macromolecule metabolic process macromolecule metabolic process regulation of metabolic process positive regulation of cellular process catabolic process negative regulation of proteolysis negative regulation of proteolysis involved in protein catabolic process proteolysis involved in protein catabolic process negative regulation of biological process regulation of ubiquitin-dependent protein catabolic process macromolecule catabolic process regulation of primary metabolic process regulation of proteolysis involved in protein catabolic process regulation of proteolysis modification-dependent macromolecule catabolic process proteolysis negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of ubiquitin-dependent protein catabolic process negative regulation of macromolecule metabolic process negative regulation of catabolic process regulation of protein metabolic process negative regulation of metabolic process primary metabolic process regulation of catabolic process protein catabolic process modification-dependent protein catabolic process ubiquitin-dependent protein catabolic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing nucleobase-containing compound biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular component biogenesis RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process cellular component organization or biogenesis RNA processing rRNA metabolic process cellular response to stimulus positive regulation of cell communication positive regulation of signal transduction response to stimulus signaling positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator regulation of signal transduction regulation of programmed cell death regulation of intrinsic apoptotic signaling pathway intracellular signal transduction cell communication positive regulation of apoptotic signaling pathway positive regulation of response to stimulus regulation of intracellular signal transduction regulation of signal transduction by p53 class mediator positive regulation of signal transduction by p53 class mediator signal transduction intrinsic apoptotic signaling pathway regulation of signaling positive regulation of programmed cell death regulation of apoptotic process positive regulation of intracellular signal transduction signal transduction by p53 class mediator cell death positive regulation of apoptotic process apoptotic signaling pathway regulation of response to stimulus regulation of cell communication intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of intrinsic apoptotic signaling pathway apoptotic process regulation of intrinsic apoptotic signaling pathway by p53 class mediator programmed cell death regulation of apoptotic signaling pathway positive regulation of signaling multicellular organismal process embryonic epithelial tube formation chordate embryonic development tube formation embryo development multicellular organism development epithelial tube formation tube morphogenesis primary neural tube formation embryo development ending in birth or egg hatching epithelial tube morphogenesis system development morphogenesis of embryonic epithelium epithelium development neural tube development tube development embryonic morphogenesis morphogenesis of an epithelium nervous system development anatomical structure morphogenesis tissue morphogenesis neural tube closure neural tube formation anatomical structure formation involved in morphogenesis tube closure cytoplasmic translation translation ribosomal small subunit biogenesis negative regulation of post-translational protein modification negative regulation of ubiquitin protein ligase activity regulation of protein modification process regulation of catalytic activity regulation of protein ubiquitination negative regulation of catalytic activity regulation of transferase activity regulation of ubiquitin protein ligase activity negative regulation of ubiquitin-protein transferase activity protein ubiquitination negative regulation of transferase activity negative regulation of protein modification process regulation of ubiquitin-protein transferase activity negative regulation of protein ubiquitination regulation of protein modification by small protein conjugation or removal protein modification process negative regulation of protein modification by small protein conjugation or removal regulation of post-translational protein modification negative regulation of molecular function regulation of molecular function macromolecule modification post-translational protein modification protein modification by small protein conjugation protein modification by small protein conjugation or removal	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane centrosome microtubule organizing center cytoskeleton microtubule cytoskeleton cytoplasm cytosol nucleoplasm ribosome protein-containing complex cytosolic ribosome preribosome ribonucleoprotein complex small-subunit processome synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit endoplasmic reticulum endomembrane system
I [auth SI]	40S ribosomal protein S8	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process maturation of SSU-rRNA cellular component organization or biogenesis RNA processing rRNA metabolic process nucleobase-containing compound biosynthetic process ribosomal small subunit biogenesis nucleic acid metabolic process	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane cytosolic ribosome ribosome cytoplasm cytosol preribosome protein-containing complex ribonucleoprotein complex small-subunit processome extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit nucleoplasm endoplasmic reticulum endomembrane system
J [auth SK]	40S ribosomal protein S10	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane cytosolic ribosome ribosome cytoplasm cytosol cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex nucleoplasm
L [auth SP]	40S ribosomal protein S15	protein binding binding MDM2/MDM4 family protein binding RNA binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome DNA binding enzyme regulator activity molecular function inhibitor activity ubiquitin-protein transferase regulator activity ubiquitin-protein transferase inhibitor activity ubiquitin ligase inhibitor activity protein binding binding MDM2/MDM4 family protein binding RNA binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome DNA binding enzyme regulator activity molecular function inhibitor activity ubiquitin-protein transferase regulator activity ubiquitin-protein transferase inhibitor activity ubiquitin ligase inhibitor activity molecular function regulator activity enzyme inhibitor activity	cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction regulation of signal transduction by p53 class mediator positive regulation of signal transduction by p53 class mediator cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction regulation of signal transduction by p53 class mediator positive regulation of signal transduction by p53 class mediator signal transduction positive regulation of cellular process regulation of biological process regulation of signaling biological regulation positive regulation of intracellular signal transduction signal transduction by p53 class mediator regulation of response to stimulus regulation of cell communication cellular process positive regulation of signaling developmental process multicellular organismal process cellular developmental process ossification cell differentiation osteoblast differentiation establishment of organelle localization cellular localization ribonucleoprotein complex biogenesis nucleocytoplasmic transport transport nuclear transport ribosomal subunit export from nucleus intracellular transport establishment of localization protein-containing complex localization cellular component biogenesis localization ribosome biogenesis ribosomal small subunit export from nucleus organelle localization establishment of localization in cell cellular component organization or biogenesis nuclear export ribosome localization RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process biosynthetic process metabolic process macromolecule metabolic process RNA processing rRNA metabolic process gland development animal organ development animal organ regeneration liver development regeneration multicellular organism development hepaticobiliary system development anatomical structure development liver regeneration system development cytoplasmic translation protein metabolic process translation ribosomal small subunit biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly cellular component organization organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly ribosome assembly	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane intracellular anatomical structure cytoplasm cytosol membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane intracellular anatomical structure cytoplasm cytosol membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle nucleoplasm organelle lumen organelle nuclear lumen cytosolic ribosome membraneless organelle intracellular membraneless organelle ribosome synapse cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex
M [auth SQ]	40S ribosomal protein S16	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process maturation of SSU-rRNA cellular component organization or biogenesis RNA processing rRNA metabolic process nucleobase-containing compound biosynthetic process ribosomal small subunit biogenesis nucleic acid metabolic process response to peptide response to stimulus response to chemical response to cytokine response to leukemia inhibitory factor cellular response to cytokine stimulus cellular response to leukemia inhibitory factor	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex ribosome membrane cytosolic ribosome cytoplasm cytosol preribosome small-subunit processome extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle synapse cytosolic small ribosomal subunit nucleoplasm
N [auth SR]	40S ribosomal protein S17	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process translational initiation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cytoplasmic translation cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis biosynthetic process translational initiation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cytoplasmic translation cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis RNA metabolic process rRNA processing nucleobase-containing compound biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process RNA processing rRNA metabolic process multicellular organismal process multicellular organismal-level homeostasis homeostatic process immune system process homeostasis of number of cells myeloid cell homeostasis erythrocyte homeostasis	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane cytosolic ribosome ribosome cytoplasm cytosol preribosome protein-containing complex ribonucleoprotein complex small-subunit processome synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit nucleoplasm
O [auth SS]	40S ribosomal protein S18	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle organelle ribonucleoprotein complex membraneless organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle organelle ribonucleoprotein complex membraneless organelle ribosome membrane cytosolic ribosome cytoplasm cytosol extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization synapse asymmetric synapse cytosolic small ribosomal subunit nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen
P [auth ST]	40S ribosomal protein S19	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome fibroblast growth factor binding protein binding growth factor binding kinase binding enzyme binding protein kinase binding identical protein binding	regulation of immune effector process multicellular organismal process positive regulation of response to biotic stimulus regulation of cellular process positive regulation of respiratory burst response to stimulus response to biotic stimulus positive regulation of metabolic process regulation of respiratory burst involved in inflammatory response positive regulation of immune response positive regulation of inflammatory response regulation of immune system process positive regulation of immune system process regulation of biological process regulation of immune effector process multicellular organismal process positive regulation of response to biotic stimulus regulation of cellular process positive regulation of respiratory burst response to stimulus response to biotic stimulus positive regulation of metabolic process regulation of respiratory burst involved in inflammatory response positive regulation of immune response positive regulation of inflammatory response regulation of immune system process positive regulation of immune system process regulation of biological process respiratory burst involved in defense response immune response response to other organism regulation of innate immune response response to external stimulus regulation of inflammatory response immune effector process regulation of response to stimulus defense response to other organism respiratory burst involved in inflammatory response positive regulation of defense response regulation of immune response positive regulation of multicellular organismal process metabolic process inflammatory response regulation of metabolic process regulation of defense response regulation of response to biotic stimulus biological process involved in interspecies interaction between organisms regulation of response to external stimulus positive regulation of biological process positive regulation of response to stimulus positive regulation of response to external stimulus response to stress regulation of response to stress innate immune response regulation of multicellular organismal process positive regulation of immune effector process response to external biotic stimulus regulation of respiratory burst positive regulation of cellular process production of molecular mediator involved in inflammatory response positive regulation of innate immune response positive regulation of respiratory burst involved in inflammatory response defense response biological regulation defense response to symbiont respiratory burst immune system process cellular process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process maturation of SSU-rRNA cellular component organization or biogenesis RNA processing rRNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process ribosomal small subunit biogenesis nucleic acid metabolic process biosynthetic process macromolecule metabolic process cellular component organization nucleus organization organelle organization nucleolus organization cytoplasmic translation protein metabolic process translation cell chemotaxis cellular response to stimulus chemotaxis monocyte chemotaxis leukocyte migration cellular response to chemical stimulus taxis response to chemical mononuclear cell migration myeloid leukocyte migration cell migration cell motility leukocyte chemotaxis locomotion humoral immune response antimicrobial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide developmental process cellular developmental process homeostatic process hemopoiesis cell development erythrocyte differentiation multicellular organismal-level homeostasis myeloid cell differentiation cell differentiation anatomical structure development homeostasis of number of cells myeloid cell homeostasis erythrocyte homeostasis disruption of cell in another organism disruption of anatomical structure in another organism killing of cells of another organism cell killing negative regulation of biological process regulation of cell differentiation regulation of cell development negative regulation of immune response negative regulation of metabolic process negative regulation of immune effector process negative regulation of response to external stimulus negative regulation of defense response negative regulation of respiratory burst involved in inflammatory response negative regulation of multicellular organismal process regulation of developmental process negative regulation of response to biotic stimulus negative regulation of inflammatory response negative regulation of respiratory burst negative regulation of cellular process negative regulation of response to stimulus negative regulation of immune system process negative regulation of innate immune response defense response to Gram-negative bacterium defense response to bacterium response to bacterium organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly protein-RNA complex organization cellular component assembly protein-containing complex assembly ribosome assembly	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle cytoplasm cytosol nucleoplasm ribosome cytosolic ribosome preribosome protein-containing complex ribonucleoprotein complex small-subunit processome postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization synapse asymmetric synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit
Q [auth SU]	40S ribosomal protein S20	enzyme regulator activity molecular function inhibitor activity ubiquitin-protein transferase regulator activity ubiquitin-protein transferase inhibitor activity ubiquitin ligase inhibitor activity molecular function regulator activity enzyme inhibitor activity protein binding binding MDM2/MDM4 family protein binding RNA binding organic cyclic compound binding nucleic acid binding structural molecule activity enzyme regulator activity molecular function inhibitor activity ubiquitin-protein transferase regulator activity ubiquitin-protein transferase inhibitor activity ubiquitin ligase inhibitor activity molecular function regulator activity enzyme inhibitor activity protein binding binding MDM2/MDM4 family protein binding RNA binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction regulation of signal transduction by p53 class mediator positive regulation of signal transduction by p53 class mediator cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling positive regulation of biological process regulation of signal transduction intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction regulation of signal transduction by p53 class mediator positive regulation of signal transduction by p53 class mediator signal transduction positive regulation of cellular process regulation of biological process regulation of signaling biological regulation positive regulation of intracellular signal transduction signal transduction by p53 class mediator regulation of response to stimulus regulation of cell communication cellular process positive regulation of signaling biosynthetic process cytoplasmic translation metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	cellular anatomical structure membrane intracellular organelle intracellular anatomical structure cytosolic ribosome organelle membraneless organelle intracellular membraneless organelle ribosome cytoplasm cytosol extracellular exosome membrane-bounded organelle extracellular vesicle cellular anatomical structure membrane intracellular organelle intracellular anatomical structure cytosolic ribosome organelle membraneless organelle intracellular membraneless organelle ribosome cytoplasm cytosol extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle synapse cell junction cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen
R [auth SV]	40S ribosomal protein S21	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process maturation of SSU-rRNA RNA 3'-end processing cellular component organization or biogenesis RNA processing rRNA metabolic process endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleobase-containing compound biosynthetic process ribosomal small subunit biogenesis nucleic acid metabolic process endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) rRNA 3'-end processing endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure organelle ribonucleoprotein complex membraneless organelle ribosome cytosolic ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure organelle ribonucleoprotein complex membraneless organelle ribosome cytosolic ribosome cytoplasm cytosol synapse cell junction cytosolic small ribosomal subunit membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen rough endoplasmic reticulum endoplasmic reticulum endomembrane system
S [auth SX]	40S ribosomal protein S23	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis cellular component organization organelle organization cellular component assembly stress granule assembly organelle assembly membraneless organelle assembly maintenance of translational fidelity	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane cytosolic ribosome ribosome cytoplasm cytosol preribosome protein-containing complex ribonucleoprotein complex small-subunit processome synapse cell junction cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit nucleoplasm rough endoplasmic reticulum endoplasmic reticulum endomembrane system
T [auth Sa]	40S ribosomal protein S26	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding cell adhesion molecule binding cadherin binding protein binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process regulation of cellular process negative regulation of biological process RNA metabolic process regulation of primary metabolic process biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process regulation of cellular process negative regulation of biological process RNA metabolic process regulation of primary metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process nucleic acid biosynthetic process negative regulation of cellular process RNA processing negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process RNA splicing negative regulation of metabolic process biological regulation regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process regulation of RNA splicing nucleic acid metabolic process negative regulation of RNA splicing regulation of gene expression negative regulation of gene expression negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process regulation of metabolic process	protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure organelle ribonucleoprotein complex membraneless organelle ribosome membrane extracellular exosome membrane-bounded organelle protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure organelle ribonucleoprotein complex membraneless organelle ribosome membrane extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle synapse cell junction organelle subcompartment cytoplasmic side of membrane intracellular membrane-bounded organelle endomembrane system side of membrane cytoplasmic side of rough endoplasmic reticulum membrane rough endoplasmic reticulum endoplasmic reticulum subcompartment bounding membrane of organelle rough endoplasmic reticulum membrane nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum cytoplasmic side of endoplasmic reticulum membrane cytoplasm organelle membrane endoplasmic reticulum membrane cytosol cytosolic small ribosomal subunit cytosolic ribosome nucleus membrane-enclosed lumen intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen
U [auth Sc]	40S ribosomal protein S28	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis RNA metabolic process rRNA processing nucleobase-containing compound biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process RNA processing rRNA metabolic process organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly cellular component organization organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly ribosome assembly maturation of SSU-rRNA	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex ribosome preribosome small-subunit processome extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle synapse cell junction organelle subcompartment cytoplasmic side of membrane membrane endomembrane system side of membrane cytoplasmic side of rough endoplasmic reticulum membrane rough endoplasmic reticulum endoplasmic reticulum subcompartment bounding membrane of organelle rough endoplasmic reticulum membrane nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum cytoplasmic side of endoplasmic reticulum membrane cytoplasm organelle membrane endoplasmic reticulum membrane cytosol cytosolic small ribosomal subunit cytosolic ribosome nucleoplasm
V [auth Sd]	40S ribosomal protein S29	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle organelle ribonucleoprotein complex membraneless organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle organelle ribonucleoprotein complex membraneless organelle ribosome extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle organelle subcompartment cytoplasmic side of membrane membrane intracellular membrane-bounded organelle endomembrane system side of membrane cytoplasmic side of rough endoplasmic reticulum membrane rough endoplasmic reticulum endoplasmic reticulum subcompartment bounding membrane of organelle rough endoplasmic reticulum membrane nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum cytoplasmic side of endoplasmic reticulum membrane cytoplasm organelle membrane endoplasmic reticulum membrane cytosol cytosolic small ribosomal subunit cytosolic ribosome nucleus membrane-enclosed lumen intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen
W [auth Sg]	Receptor of activated protein C kinase 1	molecular function inhibitor activity channel regulator activity transporter inhibitor activity ion channel inhibitor activity ion channel regulator activity molecular function regulator activity transporter regulator activity channel inhibitor activity protein phosphatase binding phosphatase binding protein binding binding enzyme binding death domain binding molecular function inhibitor activity channel regulator activity transporter inhibitor activity ion channel inhibitor activity ion channel regulator activity molecular function regulator activity transporter regulator activity channel inhibitor activity protein phosphatase binding phosphatase binding protein binding binding enzyme binding death domain binding BH3 domain binding BH domain binding protein domain specific binding cell adhesion molecule binding cadherin binding enzyme regulator activity enzyme activator activity peptidase regulator activity molecular function activator activity cysteine-type endopeptidase activator activity involved in apoptotic process cysteine-type endopeptidase regulator activity involved in apoptotic process peptidase activator activity peptidase activator activity involved in apoptotic process molecular adaptor activity protein tyrosine kinase binding kinase binding signaling receptor binding receptor tyrosine kinase binding protein kinase binding identical protein binding translation regulator activity protein-macromolecule adaptor activity signaling adaptor activity SH2 domain binding cyclin binding RNA binding organic cyclic compound binding nucleic acid binding protein homodimerization activity protein dimerization activity protein kinase inhibitor activity protein tyrosine kinase inhibitor activity enzyme inhibitor activity protein kinase regulator activity kinase inhibitor activity kinase regulator activity ribonucleoprotein complex binding protein-containing complex binding ribosome binding protein kinase C binding	protein localization positive regulation of protein localization to plasma membrane regulation of localization Golgi to plasma membrane transport establishment of protein localization nitrogen compound transport regulation of cellular process establishment of protein localization to plasma membrane positive regulation of establishment of protein localization Golgi to plasma membrane protein transport vesicle-mediated transport localization cellular macromolecule localization positive regulation of protein localization to cell periphery protein localization positive regulation of protein localization to plasma membrane regulation of localization Golgi to plasma membrane transport establishment of protein localization nitrogen compound transport regulation of cellular process establishment of protein localization to plasma membrane positive regulation of establishment of protein localization Golgi to plasma membrane protein transport vesicle-mediated transport localization cellular macromolecule localization positive regulation of protein localization to cell periphery positive regulation of Golgi to plasma membrane protein transport regulation of biological process protein localization to cell periphery establishment of protein localization to membrane positive regulation of protein localization to membrane localization within membrane regulation of protein localization to cell periphery protein localization to membrane establishment of localization regulation of Golgi to plasma membrane protein transport positive regulation of protein localization Golgi vesicle transport cellular localization post-Golgi vesicle-mediated transport regulation of protein localization transport positive regulation of biological process positive regulation of protein transport regulation of protein localization to membrane positive regulation of cellular process regulation of transport protein localization to plasma membrane biological regulation regulation of establishment of protein localization regulation of protein transport regulation of vesicle-mediated transport vesicle-mediated transport to the plasma membrane positive regulation of transport protein transport regulation of cellular localization macromolecule localization cellular process regulation of protein localization to plasma membrane regulation of protein binding regulation of molecular function negative regulation of protein binding negative regulation of binding regulation of binding negative regulation of molecular function cellular component disassembly ribosome disassembly rescue of stalled ribosome primary metabolic process translation gene expression macromolecule biosynthetic process cellular component organization organelle organization organelle disassembly biosynthetic process translational elongation metabolic process cellular component organization or biogenesis macromolecule metabolic process protein metabolic process developmental process multicellular organismal process regulation of embryonic development regulation of multicellular organismal development regulation of gastrulation regulation of developmental process embryonic morphogenesis positive regulation of gastrulation embryo development gastrulation positive regulation of developmental process multicellular organism development anatomical structure morphogenesis anatomical structure development positive regulation of embryonic development positive regulation of multicellular organismal process regulation of multicellular organismal process regulation of anatomical structure morphogenesis positive regulation of cellular component organization regulation of cellular component organization protein-containing complex organization positive regulation of cellular component biogenesis regulation of cellular component biogenesis cellular component biogenesis positive regulation of protein-containing complex assembly regulation of protein-containing complex assembly cellular component assembly protein-containing complex assembly positive regulation of programmed cell death regulation of apoptotic process regulation of programmed cell death cell death positive regulation of apoptotic process apoptotic process programmed cell death regulation of growth negative regulation of biological process growth negative regulation of cell growth regulation of cell growth cell growth negative regulation of growth negative regulation of cellular process regulation of mitochondrial depolarization positive regulation of membrane depolarization positive regulation of mitochondrial depolarization mitochondrial depolarization regulation of membrane depolarization regulation of mitochondrial membrane potential membrane depolarization regulation of biological quality regulation of membrane potential positive regulation of proteasomal protein catabolic process catabolic process positive regulation of protein metabolic process proteolysis involved in protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process macromolecule catabolic process regulation of ubiquitin-dependent protein catabolic process regulation of primary metabolic process positive regulation of metabolic process positive regulation of ubiquitin-dependent protein catabolic process regulation of proteolysis regulation of proteolysis involved in protein catabolic process modification-dependent macromolecule catabolic process proteolysis positive regulation of macromolecule metabolic process regulation of protein metabolic process proteasomal protein catabolic process regulation of macromolecule metabolic process protein catabolic process regulation of catabolic process positive regulation of protein catabolic process positive regulation of proteolysis involved in protein catabolic process positive regulation of catabolic process regulation of proteasomal ubiquitin-dependent protein catabolic process modification-dependent protein catabolic process positive regulation of proteolysis regulation of proteasomal protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process regulation of metabolic process regulation of protein catabolic process protein ubiquitination macromolecule modification post-translational protein modification protein modification process protein modification by small protein conjugation protein modification by small protein conjugation or removal cellular response to stimulus regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction response to stimulus signaling negative regulation of signaling negative regulation of intracellular signal transduction negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of signal transduction intracellular signal transduction negative regulation of cell communication cell communication regulation of intracellular signal transduction intracellular signaling cassette signal transduction regulation of signaling negative regulation of response to stimulus negative regulation of signal transduction regulation of response to stimulus regulation of cell communication phosphatidylinositol 3-kinase/protein kinase B signal transduction adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway regulation of G protein-coupled receptor signaling pathway positive regulation of cell communication positive regulation of signal transduction regulation of intrinsic apoptotic signaling pathway positive regulation of apoptotic signaling pathway positive regulation of response to stimulus intrinsic apoptotic signaling pathway positive regulation of intracellular signal transduction apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway regulation of apoptotic signaling pathway positive regulation of signaling cell division regulation of cell division pigmentation regulation of cellular response to stress endoplasmic reticulum unfolded protein response regulation of response to endoplasmic reticulum stress regulation of endoplasmic reticulum unfolded protein response cellular response to stress response to stress regulation of response to stress negative regulation of endoplasmic reticulum unfolded protein response response to endoplasmic reticulum stress negative regulation of response to endoplasmic reticulum stress cellular response to topologically incorrect protein cellular response to unfolded protein response to unfolded protein response to topologically incorrect protein negative regulation of Wnt signaling pathway Wnt signaling pathway cell surface receptor signaling pathway regulation of Wnt signaling pathway post-transcriptional regulation of gene expression negative regulation of translation negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process negative regulation of metabolic process regulation of gene expression negative regulation of gene expression negative regulation of biosynthetic process regulation of translation negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process homeostatic process response to oxygen-containing compound cellular response to glucose stimulus intracellular glucose homeostasis cellular response to oxygen-containing compound response to hexose cellular response to carbohydrate stimulus cellular response to chemical stimulus cellular homeostasis response to monosaccharide response to carbohydrate chemical homeostasis response to glucose response to chemical glucose homeostasis carbohydrate homeostasis cellular response to hexose stimulus intracellular chemical homeostasis cellular response to monosaccharide stimulus positive regulation of molecular function positive regulation of hydrolase activity regulation of catalytic activity regulation of hydrolase activity positive regulation of catalytic activity regulation of GTPase activity positive regulation of GTPase activity regulation of protein modification process regulation of protein phosphorylation negative regulation of phosphate metabolic process regulation of peptidyl-serine phosphorylation peptidyl-serine modification peptidyl-serine phosphorylation regulation of phosphate metabolic process phosphate-containing compound metabolic process negative regulation of protein modification process peptidyl-amino acid modification phosphorus metabolic process negative regulation of peptidyl-serine phosphorylation protein phosphorylation phosphorylation negative regulation of protein phosphorylation negative regulation of phosphorus metabolic process regulation of phosphorylation regulation of phosphorus metabolic process negative regulation of phosphorylation regulation of hydrogen peroxide-mediated programmed cell death programmed cell death in response to reactive oxygen species negative regulation of apoptotic signaling pathway negative regulation of programmed cell death negative regulation of apoptotic process intrinsic apoptotic signaling pathway in response to oxidative stress regulation of oxidative stress-induced intrinsic apoptotic signaling pathway cellular response to oxidative stress cellular response to chemical stress negative regulation of hydrogen peroxide-mediated programmed cell death cellular response to reactive oxygen species hydrogen peroxide-mediated programmed cell death negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway intrinsic apoptotic signaling pathway in response to hydrogen peroxide response to reactive oxygen species negative regulation of intrinsic apoptotic signaling pathway response to oxidative stress negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide negative regulation of smoothened signaling pathway regulation of smoothened signaling pathway smoothened signaling pathway cytoplasmic translation rhythmic process cellular response to endogenous stimulus cellular response to growth factor stimulus response to endogenous stimulus response to growth factor positive regulation of locomotion regulation of cell motility positive regulation of cell migration regulation of locomotion positive regulation of cell motility regulation of cell migration cell migration cell motility locomotion import into cell negative regulation of transport negative regulation of endocytosis negative regulation of phagocytosis phagocytosis regulation of endocytosis negative regulation of cellular component organization regulation of phagocytosis endocytosis positive regulation of phosphorylation positive regulation of phosphate metabolic process positive regulation of protein modification process positive regulation of protein phosphorylation positive regulation of phosphorus metabolic process cell cycle regulation of cell cycle regulation of establishment of cell polarity regulation of establishment or maintenance of cell polarity establishment of cell polarity establishment or maintenance of cell polarity	somatodendritic compartment cell body cellular anatomical structure perikaryon neuronal cell body extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle somatodendritic compartment cell body cellular anatomical structure perikaryon neuronal cell body extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle intracellular anatomical structure cytoplasm cytosol cell projection dendrite dendritic tree neuron projection plasma membrane bounded cell projection protein-containing complex small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle ribonucleoprotein complex membraneless organelle ribosome IRE1-RACK1-PP2A complex perinuclear region of cytoplasm phagocytic cup cell periphery plasma membrane membrane mitochondrion intracellular membrane-bounded organelle midbody nucleus membrane-enclosed lumen intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen cytosolic small ribosomal subunit cytosolic ribosome
X [auth SC]	40S ribosomal protein S2	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome fibroblast growth factor binding protein binding growth factor binding mRNA binding cell adhesion molecule binding cadherin binding enzyme binding	regulation of cellular process regulation of protein modification process regulation of catalytic activity positive regulation of protein metabolic process positive regulation of biological process regulation of protein ubiquitination regulation of transferase activity positive regulation of post-translational protein modification regulation of primary metabolic process positive regulation of metabolic process positive regulation of molecular function positive regulation of protein modification process protein ubiquitination positive regulation of macromolecule metabolic process regulation of cellular process regulation of protein modification process regulation of catalytic activity positive regulation of protein metabolic process positive regulation of biological process regulation of protein ubiquitination regulation of transferase activity positive regulation of post-translational protein modification regulation of primary metabolic process positive regulation of metabolic process positive regulation of molecular function positive regulation of protein modification process protein ubiquitination positive regulation of macromolecule metabolic process regulation of ubiquitin-protein transferase activity protein metabolic process regulation of protein modification by small protein conjugation or removal protein modification process positive regulation of cellular process positive regulation of protein modification by small protein conjugation or removal positive regulation of protein ubiquitination regulation of biological process positive regulation of transferase activity regulation of post-translational protein modification regulation of protein metabolic process biological regulation positive regulation of catalytic activity primary metabolic process regulation of macromolecule metabolic process positive regulation of ubiquitin-protein transferase activity regulation of molecular function macromolecule modification metabolic process cellular process macromolecule metabolic process post-translational protein modification regulation of metabolic process protein modification by small protein conjugation protein modification by small protein conjugation or removal biosynthetic process cytoplasmic translation translation gene expression macromolecule biosynthetic process	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle intracellular anatomical structure cytoplasm cytosol nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle nucleoplasm organelle lumen nuclear lumen cytosolic ribosome membraneless organelle intracellular membraneless organelle ribosome cytosolic small ribosomal subunit protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex
Y [auth SG]	40S ribosomal protein S6	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome protein binding kinase binding enzyme binding protein kinase binding	developmental process multicellular organismal process erythrocyte development cellular developmental process homeostatic process hemopoiesis cell development erythrocyte differentiation multicellular organismal-level homeostasis myeloid cell differentiation immune system process cell differentiation anatomical structure development myeloid cell development developmental process multicellular organismal process erythrocyte development cellular developmental process homeostatic process hemopoiesis cell development erythrocyte differentiation multicellular organismal-level homeostasis myeloid cell differentiation immune system process cell differentiation anatomical structure development myeloid cell development homeostasis of number of cells cellular process myeloid cell homeostasis erythrocyte homeostasis placenta development animal organ development regulation of biological process regulation of cellular process negative regulation of programmed cell death regulation of apoptotic process biological regulation negative regulation of biological process regulation of programmed cell death cell death negative regulation of apoptotic process negative regulation of cellular process apoptotic process programmed cell death multicellular organism development anatomical structure morphogenesis embryonic morphogenesis embryo development gastrulation sexual reproduction reproductive process multicellular organismal reproductive process oogenesis cellular process involved in reproduction in multicellular organism female gamete generation developmental process involved in reproduction gamete generation germ cell development mammalian oogenesis stage positive regulation of programmed cell death positive regulation of biological process positive regulation of apoptotic process positive regulation of cellular process ribonucleoprotein complex biogenesis RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular component biogenesis RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process biosynthetic process metabolic process macromolecule metabolic process cellular component organization or biogenesis RNA processing rRNA metabolic process leukocyte apoptotic process lymphocyte apoptotic process leukocyte homeostasis T cell homeostasis activation-induced cell death of T cells T cell apoptotic process lymphocyte homeostasis cell activation mononuclear cell differentiation lymphocyte activation lymphocyte differentiation leukocyte activation T cell differentiation in thymus T cell activation T cell differentiation leukocyte differentiation cell population proliferation positive regulation of cell population proliferation regulation of cell population proliferation cytoplasmic translation protein metabolic process translation mitotic cell cycle process cell cycle phase transition cell cycle G1/S transition of mitotic cell cycle cell cycle G1/S phase transition mitotic cell cycle mitotic cell cycle phase transition cell cycle process ribosomal small subunit biogenesis cellular response to stimulus TOR signaling response to stimulus signaling intracellular signal transduction cell communication signal transduction immune response cell activation involved in immune response leukocyte proliferation immune effector process T cell proliferation involved in immune response T cell activation involved in immune response mononuclear cell proliferation lymphocyte proliferation leukocyte activation involved in immune response lymphocyte activation involved in immune response T cell proliferation chemical homeostasis glucose homeostasis carbohydrate homeostasis	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane cytoplasm cytosol somatodendritic compartment cell projection dendrite dendritic tree neuron projection plasma membrane bounded cell projection nucleoplasm cytoplasmic ribonucleoprotein granule supramolecular complex ribonucleoprotein granule protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex ribosome cytosolic ribosome preribosome small-subunit processome perinuclear region of cytoplasm cell body cytosolic small ribosomal subunit endoplasmic reticulum endomembrane system
Z [auth SJ]	40S ribosomal protein S9	translation regulator activity RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	regulation of biological process cell population proliferation regulation of cellular process positive regulation of cell population proliferation regulation of cell population proliferation biological regulation positive regulation of biological process cellular process positive regulation of cellular process biosynthetic process cytoplasmic translation metabolic process primary metabolic process protein metabolic process regulation of biological process cell population proliferation regulation of cellular process positive regulation of cell population proliferation regulation of cell population proliferation biological regulation positive regulation of biological process cellular process positive regulation of cellular process biosynthetic process cytoplasmic translation metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle cytoplasm cytosol nucleoplasm ribosome cytosolic ribosome preribosome protein-containing complex ribonucleoprotein complex small-subunit processome synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit
AA [auth SM]	40S ribosomal protein S12	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis cellular response to stimulus positive regulation of cell communication regulation of cellular process positive regulation of signal transduction response to stimulus signaling regulation of canonical Wnt signaling pathway canonical Wnt signaling pathway positive regulation of biological process regulation of signal transduction cell communication positive regulation of response to stimulus positive regulation of Wnt signaling pathway signal transduction Wnt signaling pathway positive regulation of cellular process positive regulation of canonical Wnt signaling pathway regulation of biological process regulation of signaling cell surface receptor signaling pathway regulation of Wnt signaling pathway biological regulation regulation of response to stimulus regulation of cell communication positive regulation of signaling maintenance of translational fidelity	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane cytosolic ribosome ribosome cytoplasm cytosol Golgi apparatus endomembrane system preribosome protein-containing complex ribonucleoprotein complex small-subunit processome cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit nucleoplasm
BA [auth SN]	40S ribosomal protein S13	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome mRNA binding small ribosomal subunit rRNA binding rRNA binding mRNA 5'-UTR binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process regulation of cellular process negative regulation of biological process RNA metabolic process regulation of primary metabolic process biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process regulation of cellular process negative regulation of biological process RNA metabolic process regulation of primary metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process nucleic acid biosynthetic process negative regulation of cellular process RNA processing negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process RNA splicing negative regulation of metabolic process biological regulation regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process regulation of RNA splicing nucleic acid metabolic process negative regulation of RNA splicing regulation of gene expression negative regulation of gene expression negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process regulation of metabolic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle cytoplasm cytosol nucleoplasm ribosome cytosolic ribosome preribosome protein-containing complex ribonucleoprotein complex small-subunit processome postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization synapse asymmetric synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit
DA [auth SW]	40S ribosomal protein S15a	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	regulation of biological process regulation of cellular process biological regulation positive regulation of biological process cellular process cell cycle regulation of cell cycle positive regulation of cell cycle positive regulation of cellular process cell population proliferation positive regulation of cell population proliferation regulation of cell population proliferation biosynthetic process cytoplasmic translation regulation of biological process regulation of cellular process biological regulation positive regulation of biological process cellular process cell cycle regulation of cell cycle positive regulation of cell cycle positive regulation of cellular process cell population proliferation positive regulation of cell population proliferation regulation of cell population proliferation biosynthetic process cytoplasmic translation metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis biological process involved in interspecies interaction between organisms response to stimulus response to other organism response to external stimulus response to external biotic stimulus response to virus response to biotic stimulus	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane cytosolic ribosome ribosome cytoplasm cytosol preribosome protein-containing complex ribonucleoprotein complex small-subunit processome extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle synapse cell junction cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit nucleoplasm
EA [auth SY]	40S ribosomal protein S24	protein binding binding translation initiation factor binding RNA binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis RNA metabolic process rRNA processing nucleobase-containing compound biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process RNA processing rRNA metabolic process multicellular organismal process multicellular organismal-level homeostasis homeostatic process immune system process homeostasis of number of cells myeloid cell homeostasis erythrocyte homeostasis	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex ribosome membrane cytosolic ribosome cytoplasm cytosol preribosome small-subunit processome cytosolic small ribosomal subunit nucleoplasm endoplasmic reticulum endomembrane system
FA [auth SZ]	40S ribosomal protein S25	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis RNA metabolic process rRNA processing nucleobase-containing compound biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process RNA processing rRNA metabolic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen protein-containing complex small ribosomal subunit ribosomal subunit ribonucleoprotein complex ribosome cytosolic ribosome cytoplasm cytosol extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization synapse cell junction asymmetric synapse cytosolic small ribosomal subunit nucleoplasm
GA [auth Sb]	40S ribosomal protein S27	DNA binding binding organic cyclic compound binding nucleic acid binding cation binding transition metal ion binding zinc ion binding ion binding metal ion binding small molecule binding RNA binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis RNA metabolic process rRNA processing nucleobase-containing compound biosynthetic process nucleic acid metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process RNA processing rRNA metabolic process organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly cellular component organization organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly ribosome assembly	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen cytosolic ribosome ribosome cytoplasm cytosol preribosome protein-containing complex ribonucleoprotein complex small-subunit processome postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization synapse cell junction asymmetric synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit nucleoplasm
HA [auth Se]	40S ribosomal protein S30	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process biological process involved in interspecies interaction between organisms innate immune response in mucosa response to stimulus immune response biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process biological process involved in interspecies interaction between organisms innate immune response in mucosa response to stimulus immune response response to other organism defense response defense response to symbiont response to external stimulus response to biotic stimulus immune system process defense response to other organism response to stress innate immune response response to external biotic stimulus mucosal immune response organ or tissue specific immune response humoral immune response antimicrobial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide antibacterial humoral response defense response to bacterium response to bacterium defense response to Gram-positive bacterium	protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure organelle ribonucleoprotein complex membraneless organelle ribosome cytosolic ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure small ribosomal subunit intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure organelle ribonucleoprotein complex membraneless organelle ribosome cytosolic ribosome cytoplasm cytosol cytosolic small ribosomal subunit extracellular region extracellular space membrane-bounded organelle nucleus membrane-enclosed lumen intracellular membrane-bounded organelle intracellular organelle lumen nucleoplasm organelle lumen nuclear lumen
IA [auth Sf]	Ubiquitin-40S ribosomal protein S27a	RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome protein tag activity molecular tag activity ubiquitin protein ligase binding protein binding ubiquitin-like protein ligase binding enzyme binding cation binding ion binding RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome protein tag activity molecular tag activity ubiquitin protein ligase binding protein binding ubiquitin-like protein ligase binding enzyme binding cation binding ion binding metal ion binding small molecule binding	catabolic process proteolysis involved in protein catabolic process primary metabolic process protein catabolic process macromolecule catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process protein ubiquitination macromolecule modification catabolic process proteolysis involved in protein catabolic process primary metabolic process protein catabolic process macromolecule catabolic process modification-dependent macromolecule catabolic process modification-dependent protein catabolic process proteolysis metabolic process cellular process protein metabolic process macromolecule metabolic process protein ubiquitination macromolecule modification post-translational protein modification protein modification process protein modification by small protein conjugation protein modification by small protein conjugation or removal biosynthetic process cytoplasmic translation translation gene expression macromolecule biosynthetic process	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle nuclear lumen membrane vesicle extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space extracellular membrane-bounded organelle cytoplasm cytosol cell periphery plasma membrane nucleoplasm organelle subcompartment endomembrane system endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum organelle membrane endoplasmic reticulum membrane intracellular vesicle cytoplasmic vesicle membrane bounding membrane of organelle cytoplasmic vesicle vesicle membrane endocytic vesicle membrane endocytic vesicle cytosolic ribosome ribosome preribosome protein-containing complex ribonucleoprotein complex small-subunit processome synapse cell junction endosome membrane endosome mitochondrial membrane mitochondrion organelle outer membrane organelle envelope mitochondrial envelope mitochondrial outer membrane outer membrane cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit
JA [auth JD]	La-related protein 1	mRNA 3'-UTR binding RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding RNA cap binding eukaryotic initiation factor 4E binding protein binding translation initiation factor binding translation regulator activity translation activator activity translation regulator activity, nucleic acid binding RNA 7-methylguanosine cap binding mRNA 3'-UTR binding RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding RNA cap binding eukaryotic initiation factor 4E binding protein binding translation initiation factor binding translation regulator activity translation activator activity translation regulator activity, nucleic acid binding RNA 7-methylguanosine cap binding cell adhesion molecule binding cadherin binding mRNA 5'-UTR binding ribonucleoprotein complex binding protein-containing complex binding ribosomal small subunit binding ribosome binding	biosynthetic process translational initiation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular response to stimulus cellular response to nitrogen compound response to ketone response to stimulus biosynthetic process translational initiation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular response to stimulus cellular response to nitrogen compound response to ketone response to stimulus response to alcohol cellular response to organic cyclic compound response to oxygen-containing compound response to nitrogen compound cellular response to ether cellular response to oxygen-containing compound cellular response to chemical stimulus cellular response to alcohol response to ether response to chemical response to rapamycin cellular response to rapamycin cellular response to ketone response to organic cyclic compound regulation of cellular process negative regulation of biological process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation negative regulation of cellular process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process regulation of protein metabolic process negative regulation of metabolic process biological regulation regulation of macromolecule metabolic process regulation of gene expression negative regulation of gene expression negative regulation of biosynthetic process regulation of translation negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process regulation of metabolic process response to nutrient levels response to stress response to amino acid starvation response to starvation cell population proliferation TOR signaling signaling intracellular signal transduction cell communication signal transduction TORC1 signaling positive regulation of macromolecule biosynthetic process nucleobase-containing compound metabolic process positive regulation of metabolic process regulation of RNA metabolic process negative regulation of nucleobase-containing compound metabolic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological quality RNA catabolic process mRNA stabilization mRNA catabolic process nucleobase-containing compound catabolic process nucleic acid catabolic process negative regulation of RNA metabolic process catabolic process positive regulation of biological process RNA metabolic process macromolecule catabolic process negative regulation of mRNA metabolic process regulation of mRNA catabolic process positive regulation of biosynthetic process positive regulation of cellular process negative regulation of catabolic process negative regulation of mRNA catabolic process negative regulation of RNA catabolic process regulation of catabolic process mRNA metabolic process nucleic acid metabolic process regulation of mRNA stability RNA stabilization positive regulation of gene expression regulation of RNA stability regulation of mRNA metabolic process positive regulation of protein metabolic process positive regulation of translation positive regulation of autophagy macroautophagy autophagy regulation of autophagy positive regulation of catabolic process regulation of macroautophagy positive regulation of macroautophagy process utilizing autophagic mechanism positive regulation of viral genome replication positive regulation of viral process viral life cycle regulation of viral process regulation of viral life cycle viral genome replication viral process regulation of viral genome replication regulation of translational initiation negative regulation of translational initiation positive regulation of translational initiation	intracellular anatomical structure cytoplasmic ribonucleoprotein granule intracellular membraneless organelle ribonucleoprotein granule intracellular organelle cellular anatomical structure organelle membraneless organelle cytoplasm supramolecular complex cytoplasmic stress granule membrane cytosol
K [auth SL]	40S ribosomal protein S11	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal small subunit biogenesis	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane cytosolic ribosome ribosome cytoplasm cytosol preribosome protein-containing complex ribonucleoprotein complex small-subunit processome extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit nucleoplasm
CA [auth SO]	40S ribosomal protein S14	translation regulator activity RNA binding binding organic cyclic compound binding nucleic acid binding structural molecule activity structural constituent of ribosome mRNA 5'-UTR binding mRNA binding	ribonucleoprotein complex biogenesis RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process ribosomal small subunit biogenesis nucleic acid metabolic process cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process primary metabolic process rRNA processing gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process ribosomal small subunit biogenesis nucleic acid metabolic process cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process biosynthetic process maturation of SSU-rRNA cellular process metabolic process cellular component organization or biogenesis macromolecule metabolic process RNA processing rRNA metabolic process cytoplasmic translation protein metabolic process translation developmental process multicellular organismal process cellular developmental process homeostatic process hemopoiesis cell development erythrocyte differentiation multicellular organismal-level homeostasis myeloid cell differentiation immune system process cell differentiation anatomical structure development homeostasis of number of cells myeloid cell homeostasis erythrocyte homeostasis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal small subunit assembly protein-RNA complex assembly cellular component organization organelle organization protein-RNA complex organization cellular component assembly protein-containing complex assembly ribosome assembly regulation of cellular process negative regulation of biological process regulation of primary metabolic process negative regulation of RNA biosynthetic process DNA-templated transcription regulation of RNA metabolic process transcription by RNA polymerase II negative regulation of cellular process negative regulation of nucleobase-containing compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of transcription by RNA polymerase II negative regulation of DNA-templated transcription regulation of biological process negative regulation of transcription by RNA polymerase II negative regulation of metabolic process biological regulation regulation of macromolecule metabolic process regulation of gene expression negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription regulation of metabolic process negative regulation of RNA metabolic process	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle intracellular membrane-bounded organelle nucleolus intracellular organelle lumen intracellular organelle organelle lumen organelle membraneless organelle nuclear lumen membrane extracellular exosome extracellular vesicle extracellular organelle extracellular region extracellular space vesicle extracellular membrane-bounded organelle cytoplasm cytosol nucleoplasm cytosolic ribosome ribosome preribosome protein-containing complex ribonucleoprotein complex small-subunit processome postsynaptic density postsynapse neuron to neuron synapse postsynaptic specialization synapse asymmetric synapse cytosolic small ribosomal subunit small ribosomal subunit ribosomal subunit

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth Ln]	IPR007836	Large ribosomal subunit protein eS32	Family
C [auth SA]	IPR023591	Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily	Homologous Superfamily
C [auth SA]	IPR001865	Small ribosomal subunit protein uS2	Family
C [auth SA]	IPR032281	Small ribosomal subunit protein uS2, C-terminal domain	Domain
C [auth SA]	IPR027504	Small ribosomal subunit protein uS2, vertebrates	Family
C [auth SA]	IPR005707	Small ribosomal subunit protein uS2, eukaryotic/archaeal	Family
C [auth SA]	IPR018130	Small ribosomal subunit protein uS2, conserved site	Conserved Site
C [auth SA]	IPR027498	Small ribosomal subunit protein uS2, eukaryotic	Family
D [auth SB]	IPR001593	Small ribosomal subunit protein eS1	Family
D [auth SB]	IPR018281	Small ribosomal subunit protein eS1, conserved site	Conserved Site
D [auth SB]	IPR027500	Small ribosomal subunit protein eS1, eukaryotes	Family
E [auth SD]	IPR009019	K homology domain superfamily, prokaryotic type	Homologous Superfamily
E [auth SD]	IPR015946	K homology domain-like, alpha/beta	Homologous Superfamily
E [auth SD]	IPR036419	Ribosomal protein S3, C-terminal domain superfamily	Homologous Superfamily
E [auth SD]	IPR004044	K Homology domain, type 2	Domain
E [auth SD]	IPR001351	Small ribosomal subunit protein uS3, C-terminal	Domain
E [auth SD]	IPR005703	Small ribosomal subunit protein uS3, eukaryotic/archaeal	Family
E [auth SD]	IPR018280	Small ribosomal subunit protein uS3, conserved site	Conserved Site
F [auth SE]	IPR013843	Small ribosomal subunit protein eS4, N-terminal	Domain
F [auth SE]	IPR032277	Small ribosomal subunit protein eS4, C-terminal domain	Domain
F [auth SE]	IPR013845	Small ribosomal subunit protein eS4, central region	Domain
F [auth SE]	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
F [auth SE]	IPR041982	Small ribosomal subunit protein eS4, KOW domain	Domain
F [auth SE]	IPR018199	Small ribosomal subunit protein eS4, N-terminal, conserved site	Conserved Site
F [auth SE]	IPR002942	RNA-binding S4 domain	Domain
F [auth SE]	IPR000876	Small ribosomal subunit protein eS4	Family
F [auth SE]	IPR038237	Small ribosomal subunit protein eS4, central domain superfamily	Homologous Superfamily
F [auth SE]	IPR036986	RNA-binding S4 domain superfamily	Homologous Superfamily
F [auth SE]	IPR005824	KOW	Domain
G [auth SF]	IPR023798	Small ribosomal subunit protein uS7 domain	Domain
G [auth SF]	IPR020606	Small ribosomal subunit protein uS7, conserved site	Conserved Site
G [auth SF]	IPR036823	Small ribosomal subunit protein uS7 domain superfamily	Homologous Superfamily
G [auth SF]	IPR000235	Small ribosomal subunit protein uS7	Family
G [auth SF]	IPR005716	Ribosomal protein uS7, eukaryotic/archaeal	Family
H [auth SH]	IPR000554	Small ribosomal subunit protein eS7	Family
H [auth SH]	IPR047861	Small ribosomal subunit protein eS7, conserved site	Conserved Site
I [auth SI]	IPR042563	Small ribosomal subunit protein eS8 subdomain, eukaryotes	Homologous Superfamily
I [auth SI]	IPR022309	Ribosomal protein eS8/ribosomal biogenesis NSA2	Family
I [auth SI]	IPR018283	Small ribosomal subunit protein eS8, conserved site	Conserved Site
I [auth SI]	IPR001047	Small ribosomal subunit protein eS8	Family
J [auth SK]	IPR037447	Small ribosomal subunit protein eS10	Family
J [auth SK]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
J [auth SK]	IPR005326	Plectin/eS10, N-terminal	Domain
L [auth SP]	IPR023575	Small ribosomal subunit protein uS19, superfamily	Homologous Superfamily
L [auth SP]	IPR020934	Small ribosomal subunit protein uS19, conserved site	Conserved Site
L [auth SP]	IPR005713	Small ribosomal subunit protein uS19, eukaryotic/archaeal	Family
L [auth SP]	IPR002222	Small ribosomal subunit protein uS19	Family
M [auth SQ]	IPR020574	Small ribosomal subunit protein uS9, conserved site	Conserved Site
M [auth SQ]	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	Homologous Superfamily
M [auth SQ]	IPR000754	Small ribosomal subunit protein uS9	Family
M [auth SQ]	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Homologous Superfamily
N [auth SR]	IPR001210	Small ribosomal subunit protein eS17	Family
N [auth SR]	IPR036401	Small ribosomal subunit protein eS17 superfamily	Homologous Superfamily
N [auth SR]	IPR018273	Small ribosomal subunit protein eS17, conserved site	Conserved Site
O [auth SS]	IPR018269	Small ribosomal subunit protein uS13, conserved site	Conserved Site
O [auth SS]	IPR027437	Small ribosomal subunit protein uS13, C-terminal	Homologous Superfamily
O [auth SS]	IPR001892	Small ribosomal subunit protein uS13	Family
O [auth SS]	IPR010979	Small ribosomal subunit protein uS13-like, H2TH	Homologous Superfamily
P [auth ST]	IPR018277	Small ribosomal subunit protein eS19, conserved site	Conserved Site
P [auth ST]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
P [auth ST]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily
P [auth ST]	IPR001266	Small ribosomal subunit protein eS19	Family
Q [auth SU]	IPR027486	Small ribosomal subunit protein uS10 domain	Domain
Q [auth SU]	IPR036838	Small ribosomal subunit protein uS10 domain superfamily	Homologous Superfamily
Q [auth SU]	IPR005729	Small ribosomal subunit protein uS10, eukaryotic/archaeal	Family
Q [auth SU]	IPR018268	Small ribosomal subunit protein uS10, conserved site	Conserved Site
Q [auth SU]	IPR001848	Small ribosomal subunit protein uS10	Family
R [auth SV]	IPR038579	Small ribosomal subunit protein eS21 superfamily	Homologous Superfamily
R [auth SV]	IPR018279	Small ribosomal subunit protein eS21, conserved site	Conserved Site
R [auth SV]	IPR001931	Small ribosomal subunit protein eS21	Family
S [auth SX]	IPR006032	Small ribosomal subunit protein uS12	Family
S [auth SX]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
S [auth SX]	IPR005680	Small ribosomal subunit protein uS12, eukaryotic/archaeal	Family
T [auth Sa]	IPR047864	Ribosomal protein eS26, conserved site	Conserved Site
T [auth Sa]	IPR038551	Ribosomal protein eS26 superfamily	Homologous Superfamily
T [auth Sa]	IPR000892	Small ribosomal subunit protein eS26	Family
U [auth Sc]	IPR028626	Ribosomal protein eS28 conserved site	Conserved Site
U [auth Sc]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
U [auth Sc]	IPR000289	Small ribosomal subunit protein eS28	Family
V [auth Sd]	IPR018271	Small ribosomal subunit protein uS14, conserved site	Conserved Site
V [auth Sd]	IPR043140	Small ribosomal subunit protein uS14 superfamily	Homologous Superfamily
V [auth Sd]	IPR001209	Small ribosomal subunit protein uS14	Family
V [auth Sd]	IPR039744	Small ribosomal subunit protein uS14, eukaryotes/archaea	Family
W [auth Sg]	IPR019775	WD40 repeat, conserved site	Conserved Site
W [auth Sg]	IPR036322	WD40-repeat-containing domain superfamily	Homologous Superfamily
W [auth Sg]	IPR045223	Small ribosomal subunit protein RACK1-like	Family
W [auth Sg]	IPR020472	G-protein beta WD-40 repeat	Repeat
W [auth Sg]	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily
W [auth Sg]	IPR001680	WD40 repeat	Repeat
X [auth SC]	IPR020568	Ribosomal protein uS5 domain 2-type superfamily	Homologous Superfamily
X [auth SC]	IPR018192	Small ribosomal subunit protein uS5, N-terminal, conserved site	Conserved Site
X [auth SC]	IPR014721	Small ribosomal subunit protein uS5 domain 2-type fold, subgroup	Homologous Superfamily
X [auth SC]	IPR000851	Small ribosomal subunit protein uS5	Family
X [auth SC]	IPR005711	Small ribosomal subunit protein uS5, eukaryotic/archaeal	Family
X [auth SC]	IPR005324	Small ribosomal subunit protein uS5, C-terminal	Domain
X [auth SC]	IPR013810	Small ribosomal subunit protein uS5, N-terminal	Domain
Y [auth SG]	IPR018282	Small ribosomal subunit protein eS6, conserved site	Conserved Site
Y [auth SG]	IPR001377	Small ribosomal subunit protein eS6	Family
Y [auth SG]	IPR014401	Small ribosomal subunit protein eS6-like	Family
Z [auth SJ]	IPR002942	RNA-binding S4 domain	Domain
Z [auth SJ]	IPR022801	Small ribosomal subunit protein uS4	Family
Z [auth SJ]	IPR018079	Small ribosomal subunit protein uS4, conserved site	Conserved Site
Z [auth SJ]	IPR001912	Small ribosomal subunit protein uS4, N-terminal	Domain
Z [auth SJ]	IPR005710	Small ribosomal subunit protein uS4, eukaryotic/archaeal	Family
Z [auth SJ]	IPR036986	RNA-binding S4 domain superfamily	Homologous Superfamily
AA [auth SM]	IPR000530	Small ribosomal subunit protein eS12	Family
AA [auth SM]	IPR004038	Ribosomal protein eL8/eL30/eS12/Gadd45	Domain
AA [auth SM]	IPR047860	Small ribosomal subunit protein eS12, conserved site	Conserved Site
AA [auth SM]	IPR029064	Ribosomal protein eL30-like superfamily	Homologous Superfamily
BA [auth SN]	IPR009068	uS15/NS1, RNA-binding domain superfamily	Homologous Superfamily
BA [auth SN]	IPR000589	Small ribosomal subunit protein uS15	Family
BA [auth SN]	IPR023029	Small ribosomal subunit protein uS15, archaea/eukaryotes	Family
BA [auth SN]	IPR012606	Small ribosomal subunit protein uS15, N-terminal	Domain
DA [auth SW]	IPR047863	Small ribosomal subunit protein uS8, conserved site	Conserved Site
DA [auth SW]	IPR000630	Small ribosomal subunit protein uS8	Family
DA [auth SW]	IPR035987	Small ribosomal subunit protein uS8 superfamily	Homologous Superfamily
EA [auth SY]	IPR053709	Eukaryotic Ribosomal Protein eS24	Homologous Superfamily
EA [auth SY]	IPR001976	Small ribosomal subunit protein eS24	Family
EA [auth SY]	IPR012678	Ribosomal protein uL23/eL15/eS24 core domain superfamily	Homologous Superfamily
EA [auth SY]	IPR018098	Small ribosomal subunit protein eS24 conserved site	Conserved Site
FA [auth SZ]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
FA [auth SZ]	IPR004977	Small ribosomal subunit protein eS25	Family
GA [auth Sb]	IPR023407	Small ribosomal subunit protein eS27, zinc-binding domain superfamily	Homologous Superfamily
GA [auth Sb]	IPR000592	Small ribosomal subunit protein eS27	Family
GA [auth Sb]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
HA [auth Se]	IPR019954	Ubiquitin conserved site	Conserved Site
HA [auth Se]	IPR000626	Ubiquitin-like domain	Domain
HA [auth Se]	IPR006846	Small ribosomal subunit protein eS30	Family
HA [auth Se]	IPR039415	Ubiquitin-like protein FUBI	Domain
HA [auth Se]	IPR019956	Ubiquitin domain	Domain
HA [auth Se]	IPR029071	Ubiquitin-like domain superfamily	Homologous Superfamily
IA [auth Sf]	IPR019954	Ubiquitin conserved site	Conserved Site
IA [auth Sf]	IPR050158	Ubiquitin and ubiquitin-like	Family
IA [auth Sf]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
IA [auth Sf]	IPR000626	Ubiquitin-like domain	Domain
IA [auth Sf]	IPR038582	Small ribosomal subunit protein eS31 eukaryotic-type superfamily	Homologous Superfamily
IA [auth Sf]	IPR002906	Small ribosomal subunit protein eS31	Domain
IA [auth Sf]	IPR019956	Ubiquitin domain	Domain
IA [auth Sf]	IPR029071	Ubiquitin-like domain superfamily	Homologous Superfamily
JA [auth JD]	IPR006630	La-type HTH domain	Domain
JA [auth JD]	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
JA [auth JD]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily
JA [auth JD]	IPR006607	LARP1-like, DM15 repeat	Repeat
JA [auth JD]	IPR045180	La domain containing protein	Family
K [auth SL]	IPR019979	Small ribosomal subunit protein uS17, conserved site	Conserved Site
K [auth SL]	IPR032440	Small ribosomal subunit protein uS17, N-terminal	Domain
K [auth SL]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
K [auth SL]	IPR000266	Small ribosomal subunit protein uS17	Family
K [auth SL]	IPR028333	Small ribosomal subunit protein uS17, archaeal/eukaryotic	Family
CA [auth SO]	IPR036967	Small ribosomal subunit protein uS11 superfamily	Homologous Superfamily
CA [auth SO]	IPR018102	Small ribosomal subunit protein uS11, conserved site	Conserved Site
CA [auth SO]	IPR001971	Small ribosomal subunit protein uS11	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A [auth Ln]	Pharos: P62945	diabetes mellitus
C [auth SA]	Pharos: P08865	familial isolated congenital asplenia Neoplasm Invasiveness amyotrophic lateral sclerosis lung adenocarcinoma
E [auth SD]	Pharos: P23396	melanoma Chromosomal Instability atypical teratoid rhabdoid tumor diabetes mellitus lymphoplasmacytic lymphoma Pick disease large cell medulloblastoma medulloblastoma plasma cell myeloma cutaneous melanoma lung cancer
F [auth SE]	Pharos: P62701	breast carcinoma breast cancer Malignant neoplasm of breast ovarian cancer lung cancer
G [auth SF]	Pharos: P46782	acute myeloid leukemia diabetes mellitus MALT lymphoma pancreatic intraductal papillary-mucinous neoplasm atypical teratoid rhabdoid tumor large cell medulloblastoma medulloblastoma pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia breast cancer lung cancer ovarian cancer
H [auth SH]	Pharos: P62081	Diamond-Blackfan anemia Diamond-Blackfan anemia 8 breast carcinoma Aase Smith syndrome 2 diabetes mellitus hematopoietic and lymphoid system neoplasm MALT lymphoma aplastic anemia congenital anemia inherited aplastic anemia breast cancer
I [auth SI]	Pharos: P62241	Weight Gain breast carcinoma Parkinson disease breast cancer
J [auth SK]	Pharos: P46783	Diamond-Blackfan anemia Diamond-Blackfan anemia 9 Aase Smith syndrome 2 hematopoietic and lymphoid system neoplasm aplastic anemia inherited aplastic anemia congenital anemia
L [auth SP]	Pharos: P62841	B-cell chronic lymphocytic leukemia Diamond-Blackfan anemia gastric cancer hereditary diffuse gastric adenocarcinoma B-CELL MALIGNANCY, LOW-GRADE gastric neoplasm diabetes mellitus hematopoietic and lymphoid system neoplasm
M [auth SQ]	Pharos: P62249	atypical teratoid rhabdoid tumor lung cancer osteosarcoma plasma cell myeloma glioblastoma lymphoplasmacytic lymphoma ovarian cancer primitive neuroectodermal tumor large cell medulloblastoma medulloblastoma pancreatic intraductal papillary-mucinous neoplasm
N [auth SR]	Pharos: P08708	Diamond-Blackfan anemia Diamond-Blackfan anemia 4 Aase Smith syndrome 2 hematopoietic and lymphoid system neoplasm lung cancer aplastic anemia inherited aplastic anemia ovarian cancer congenital anemia large cell medulloblastoma
O [auth SS]	Pharos: P62269	cervical cancer triple-negative breast carcinoma
P [auth ST]	Pharos: P39019	Diamond-Blackfan anemia Diamond-Blackfan anemia 1 prostate cancer large cell medulloblastoma medulloblastoma Aase Smith syndrome 2 astrocytic tumor congenital anemia glioblastoma inherited aplastic anemia lung cancer plasma cell myeloma anemia atypical teratoid rhabdoid tumor gastric cancer Diamond-Blackfan anemia Diamond-Blackfan anemia 1 prostate cancer large cell medulloblastoma medulloblastoma Aase Smith syndrome 2 astrocytic tumor congenital anemia glioblastoma inherited aplastic anemia lung cancer plasma cell myeloma anemia atypical teratoid rhabdoid tumor gastric cancer hematopoietic and lymphoid system neoplasm intellectual disability primitive neuroectodermal tumor aplastic anemia breast fibroadenoma diabetes mellitus gastric neoplasm hereditary diffuse gastric adenocarcinoma
Q [auth SU]	Pharos: P60866	adenoma cutaneous lupus erythematosus glioblastoma Hereditary Nonpolyposis Colorectal Neoplasms malignant mesothelioma psoriasis atypical teratoid rhabdoid tumor cystic fibrosis lung cancer ovarian cancer systemic lupus erythematosus breast cancer familial colorectal cancer type X Lynch syndrome prostate carcinoma
R [auth SV]	Pharos: P63220	retinal disease astrocytic tumor colorectal adenoma Disease Exacerbation gastric neoplasm large cell medulloblastoma medulloblastoma plasma cell myeloma atypical teratoid rhabdoid tumor colorectal cancer glioblastoma lung cancer oligodendroglioma prostate carcinoma benign prostatic hyperplasia retinal disease astrocytic tumor colorectal adenoma Disease Exacerbation gastric neoplasm large cell medulloblastoma medulloblastoma plasma cell myeloma atypical teratoid rhabdoid tumor colorectal cancer glioblastoma lung cancer oligodendroglioma prostate carcinoma benign prostatic hyperplasia diabetes mellitus gastric cancer hereditary diffuse gastric adenocarcinoma osteosarcoma
S [auth SX]	Pharos: P62266	brachycephaly, trichomegaly, and developmental delay intellectual disability osteosarcoma pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia breast carcinoma large cell medulloblastoma pancreatic intraductal papillary-mucinous carcinoma polycystic ovary syndrome cystic fibrosis medulloblastoma pancreatic intraductal papillary-mucinous neoplasm
T [auth Sa]	Pharos: P62854	Diamond-Blackfan anemia Diamond-Blackfan anemia 10 hypothyroidism polycystic ovary syndrome vitiligo Aase Smith syndrome 2 anorexia nervosa attention deficit hyperactivity disorder, inattentive type gastric neoplasm hematopoietic and lymphoid system neoplasm inherited aplastic anemia allergic rhinitis aplastic anemia cleft lip gastroesophageal reflux disease Diamond-Blackfan anemia Diamond-Blackfan anemia 10 hypothyroidism polycystic ovary syndrome vitiligo Aase Smith syndrome 2 anorexia nervosa attention deficit hyperactivity disorder, inattentive type gastric neoplasm hematopoietic and lymphoid system neoplasm inherited aplastic anemia allergic rhinitis aplastic anemia cleft lip gastroesophageal reflux disease hereditary diffuse gastric adenocarcinoma rheumatoid arthritis alopecia areata asthma congenital anemia gastric cancer Hashimoto thyroiditis
U [auth Sc]	Pharos: P62857	Diamond-Blackfan anemia Diamond-Blackfan anemia 15 with mandibulofacial dysostosis Weight Gain cutaneous lupus erythematosus inherited aplastic anemia metabolic syndrome X psoriasis aplastic anemia heart disease lung cancer osteosarcoma congenital anemia hematopoietic and lymphoid system neoplasm medulloblastoma ovarian cancer
V [auth Sd]	Pharos: P62273	Diamond-Blackfan anemia Diamond-Blackfan anemia 13 Aase Smith syndrome 2 glioblastoma lung cancer aplastic anemia hematopoietic and lymphoid system neoplasm malignant glioma congenital anemia inherited aplastic anemia ovarian cancer
W [auth Sg]	Pharos: P63244	squamous cell carcinoma plasma cell myeloma Alcoholic Intoxication, Chronic bipolar disorder glioblastoma lymphoplasmacytic lymphoma medulloblastoma oral cavity neoplasm pancreatic intraductal papillary-mucinous carcinoma primitive neuroectodermal tumor astrocytic tumor cystic fibrosis large cell medulloblastoma malignant glioma osteosarcoma squamous cell carcinoma plasma cell myeloma Alcoholic Intoxication, Chronic bipolar disorder glioblastoma lymphoplasmacytic lymphoma medulloblastoma oral cavity neoplasm pancreatic intraductal papillary-mucinous carcinoma primitive neuroectodermal tumor astrocytic tumor cystic fibrosis large cell medulloblastoma malignant glioma osteosarcoma pancreatic intraductal papillary-mucinous neoplasm psoriasis atypical teratoid rhabdoid tumor diabetes mellitus lung cancer oligodendroglioma ovarian cancer
X [auth SC]	Pharos: P15880	Hypoxia atrial fibrillation
Y [auth SG]	Pharos: P62753	breast carcinoma breast cancer Disease Progression hepatocellular carcinoma lung cancer gastric cancer hereditary diffuse gastric adenocarcinoma gastric neoplasm pancreatic intraductal papillary-mucinous neoplasm
Z [auth SJ]	Pharos: P46781	alcoholic liver cirrhosis prostate carcinoma lung cancer Takayasu arteritis Malignant neoplasm of breast
AA [auth SM]	Pharos: P25398	diabetes mellitus
BA [auth SN]	Pharos: P62277	diabetes mellitus primary angle-closure glaucoma
DA [auth SW]	Pharos: P62244	breast cancer glioblastoma medulloblastoma pancreatic intraductal papillary-mucinous neoplasm cystic fibrosis lung adenocarcinoma osteosarcoma pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia Diamond-Blackfan anemia malignant glioma ovarian cancer subependymal giant cell astrocytoma
EA [auth SY]	Pharos: P62847	Diamond-Blackfan anemia Diamond-Blackfan anemia 3 Aase Smith syndrome 2 lung cancer non-alcoholic fatty liver disease aplastic anemia diabetes mellitus hematopoietic and lymphoid system neoplasm lymphoplasmacytic lymphoma ovarian cancer congenital anemia inherited aplastic anemia MALT lymphoma plasma cell myeloma
FA [auth SZ]	Pharos: P62851	acute myeloid leukemia heart disease
GA [auth Sb]	Pharos: P42677	Diamond-Blackfan anemia Diamond-Blackfan anemia 17 Aase Smith syndrome 2 hematopoietic and lymphoid system neoplasm aplastic anemia inherited aplastic anemia congenital anemia prostate carcinoma
HA [auth Se]	Pharos: P62861	acne lung carcinoma metabolic syndrome X
IA [auth Sf]	Pharos: P62979	acute myeloid leukemia large cell medulloblastoma Diamond-Blackfan anemia lung carcinoma hematopoietic and lymphoid system neoplasm ulcerative colitis
JA [auth JD]	Pharos: Q6PKG0	astrocytic tumor lung cancer ovarian cancer dermatomyositis malignant glioma psoriasis large cell medulloblastoma osteosarcoma
K [auth SL]	Pharos: P62280	diabetes mellitus medulloblastoma Hodgkins lymphoma plasma cell myeloma lung cancer
CA [auth SO]	Pharos: P62263	chromosome 5q deletion syndrome carcinoma Hypoxia sarcomatoid carcinoma neutropenia undifferentiated carcinoma congenital anemia ovarian cancer breast cancer mammary neoplasms, animal