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Receptor-type tyrosine-protein phosphatase alpha

UniProtKB accession:  P18052
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Go to UniProtKB:  P18052
UniProtKB description:  Tyrosine protein phosphatase which is involved in integrin-mediated focal adhesion formation (PubMed:22801373). Following integrin engagement, specifically recruits BCAR3, BCAR1 and CRK to focal adhesions thereby promoting SRC-mediated phosphorylation of BRAC1 and the subsequent activation of PAK and small GTPase RAC1 and CDC42 (PubMed:22801373).
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