Download MendeleyThe crystal structure of adenosine deaminase in complex with chloropurine from Pseudomonas aeruginosa
Zhang, Z., Burley, S.K., Swaminathan, S.To be published.
3PBM
The crystal structure of adenosine deaminase in complex with chloropurine from Pseudomonas aeruginosa
- PDB DOI: https://doi.org/10.2210/pdb3PBM/pdb
- Classification: HYDROLASE
- Organism(s): Pseudomonas aeruginosa
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2010-10-20 Released: 2010-12-22
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.59 Å
- R-Value Free: 0.232
- R-Value Work: 0.173
- R-Value Observed: 0.176
Starting Model: experimental
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This is version 1.5 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Adenosine deaminase | 326 | Pseudomonas aeruginosa | Mutation(s): 0 Gene Names: add, PA0148 EC: 3.5.4.4 (PDB Primary Data), 3.5.4.2 (UniProt) |  | |
UniProt | |||||
Find proteins for Q9I6Y4 (Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)) Explore Q9I6Y4 Go to UniProtKB: Q9I6Y4 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9I6Y4 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ES4 Query on ES4 | D [auth A], F [auth B] | 6-chloro-9H-purine C5 H3 Cl N4 ZKBQDFAWXLTYKS-UHFFFAOYSA-N |  | ||
| ZN Query on ZN | C [auth A], E [auth B] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| MSE Query on MSE | A, B | L-PEPTIDE LINKING | C5 H11 N O2 Se |  | MET |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.59 Å
- R-Value Free: 0.232
- R-Value Work: 0.173
- R-Value Observed: 0.176
- Space Group: P 21 21 21
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 44.685 | α = 90 |
| b = 74.103 | β = 90 |
| c = 178.215 | γ = 90 |
| Software Name | Purpose |
|---|---|
| CBASS | data collection |
| PHASER | phasing |
| PHENIX | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
Entry History
Deposition Data
- Released Date: 2010-12-22 Deposition Author(s): Zhang, Z., Burley, S.K., Swaminathan, S., New York SGX Research Center for Structural Genomics (NYSGXRC)
Revision History (Full details and data files)
- Version 1.0: 2010-12-22
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2021-02-10
Changes: Database references, Derived calculations, Structure summary - Version 1.3: 2023-09-06
Changes: Data collection, Database references, Refinement description - Version 1.4: 2023-12-06
Changes: Data collection - Version 1.5: 2024-11-27
Changes: Structure summary
