Annotations: 1AXC

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1axca1	Alpha and beta proteins (a+b)	DNA clamp	DNA clamp	DNA polymerase processivity factor	Proliferating cell nuclear antigen (PCNA)	(Homo sapiens ) [TaxId: 9606 ],	SCOPe (2.08)
C	d1axcc1	Alpha and beta proteins (a+b)	DNA clamp	DNA clamp	DNA polymerase processivity factor	Proliferating cell nuclear antigen (PCNA)	(Homo sapiens ) [TaxId: 9606 ],	SCOPe (2.08)
E	d1axce1	Alpha and beta proteins (a+b)	DNA clamp	DNA clamp	DNA polymerase processivity factor	Proliferating cell nuclear antigen (PCNA)	(Homo sapiens ) [TaxId: 9606 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	DNA clamp	8032799	3000780	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	DNA clamp	8032796	3000780	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	DNA clamp	8032799	3000780	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	DNA clamp	8032796	3000780	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	DNA clamp	8032796	3000780	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	DNA clamp	8032799	3000780	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PCNA_N	e1axcA1	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: PCNA_N	ECOD (1.6)
A	PCNA_C	e1axcA2	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: PCNA_C	ECOD (1.6)
C	PCNA_N	e1axcC1	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: PCNA_N	ECOD (1.6)
C	PCNA_C	e1axcC2	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: PCNA_C	ECOD (1.6)
E	PCNA_N	e1axcE1	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: PCNA_N	ECOD (1.6)
E	PCNA_C	e1axcE2	A: a+b two layers	X: DNA clamp (From Topology)	H: DNA clamp (From Topology)	T: DNA clamp	F: PCNA_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen		CATH (4.3.0)
C	3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen		CATH (4.3.0)
E	3.70.10.10	Alpha Beta	Box	Proliferating Cell Nuclear Antigen		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C, E	PF02747	Proliferating cell nuclear antigen, C-terminal domain (PCNA_C)	Proliferating cell nuclear antigen, C-terminal domain	N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA.	Domain
A, C, E	PF00705	Proliferating cell nuclear antigen, N-terminal domain (PCNA_N)	Proliferating cell nuclear antigen, N-terminal domain	N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C, E	PCNA	protein-containing complex binding binding hydrolase activity, acting on glycosyl bonds catalytic activity, acting on DNA purine-specific mismatch base pair DNA N-glycosylase activity catalytic activity, acting on a nucleic acid hydrolase activity DNA N-glycosylase activity hydrolase activity, hydrolyzing N-glycosyl compounds catalytic activity mismatch base pair DNA N-glycosylase activity protein tyrosine kinase binding protein binding kinase binding protein-containing complex binding binding hydrolase activity, acting on glycosyl bonds catalytic activity, acting on DNA purine-specific mismatch base pair DNA N-glycosylase activity catalytic activity, acting on a nucleic acid hydrolase activity DNA N-glycosylase activity hydrolase activity, hydrolyzing N-glycosyl compounds catalytic activity mismatch base pair DNA N-glycosylase activity protein tyrosine kinase binding protein binding kinase binding signaling receptor binding receptor tyrosine kinase binding enzyme binding protein kinase binding identical protein binding chromatin binding DNA binding DNA insertion or deletion binding double-stranded DNA binding organic cyclic compound binding mismatched DNA binding dinucleotide insertion or deletion binding nucleic acid binding mismatch repair complex binding MutLalpha complex binding damaged DNA binding histone acetyltransferase binding enzyme regulator activity DNA polymerase processivity factor activity enzyme activator activity molecular function activator activity molecular function regulator activity transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding nuclear receptor binding DNA-binding transcription factor binding nuclear estrogen receptor binding DNA polymerase binding	developmental process heart development multicellular organism development multicellular organismal process anatomical structure development animal organ development circulatory system development system development nucleobase-containing compound metabolic process DNA-templated DNA replication DNA replication DNA-templated DNA replication maintenance of fidelity metabolic process primary metabolic process developmental process heart development multicellular organism development multicellular organismal process anatomical structure development animal organ development circulatory system development system development nucleobase-containing compound metabolic process DNA-templated DNA replication DNA replication DNA-templated DNA replication maintenance of fidelity metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process replication fork processing nucleic acid metabolic process leading strand elongation DNA strand elongation DNA strand elongation involved in DNA replication ovulation cycle rhythmic process estrous cycle reproductive process multicellular organismal reproductive process cellular response to stimulus mismatch repair response to stimulus cellular response to stress DNA damage response response to stress cellular process DNA repair positive regulation of nucleobase-containing compound metabolic process regulation of biological process positive regulation of DNA replication biological regulation positive regulation of biological process regulation of macromolecule metabolic process regulation of primary metabolic process positive regulation of metabolic process positive regulation of DNA metabolic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of metabolic process regulation of DNA metabolic process regulation of DNA replication epithelium development cellular developmental process cell differentiation tissue development epithelial cell differentiation postreplication repair cellular biosynthetic process DNA synthesis involved in DNA repair nucleic acid biosynthetic process translesion synthesis cellular metabolic process nucleobase-containing compound biosynthetic process macromolecule biosynthetic process biosynthetic process DNA biosynthetic process regulation of cellular process regulation of cellular response to stress positive regulation of response to stimulus positive regulation of DNA repair regulation of response to stress positive regulation of cellular process regulation of DNA repair regulation of response to stimulus response to ketone response to lipid response to endogenous stimulus response to glucocorticoid response to oxygen-containing compound response to corticosteroid response to hormone response to steroid hormone response to chemical response to dexamethasone response to organic cyclic compound response to acid chemical response to nitrogen compound response to L-glutamate response to amino acid cellular response to chemical stimulus cellular response to xenobiotic stimulus response to xenobiotic stimulus nuclear DNA replication telomere organization cell cycle DNA replication mitotic cell cycle telomere maintenance via semi-conservative replication cellular component organization mitotic telomere maintenance via semi-conservative replication cell cycle cellular component organization or biogenesis cell cycle process chromosome organization telomere maintenance organelle organization mitotic cell cycle process negative regulation of biological process RNA metabolic process negative regulation of cellular metabolic process negative regulation of RNA biosynthetic process RNA biosynthetic process DNA-templated transcription regulation of RNA metabolic process transcription by RNA polymerase II negative regulation of cellular process negative regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of transcription by RNA polymerase II negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II negative regulation of metabolic process regulation of cellular metabolic process gene expression negative regulation of cellular biosynthetic process regulation of cellular biosynthetic process regulation of gene expression negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process regulation of DNA-templated transcription negative regulation of RNA metabolic process regulation of catalytic activity positive regulation of molecular function regulation of deoxyribonuclease activity regulation of nuclease activity positive regulation of deoxyribonuclease activity positive regulation of nuclease activity positive regulation of catalytic activity regulation of molecular function positive regulation of hydrolase activity regulation of hydrolase activity regulation of transferase activity regulation of DNA biosynthetic process positive regulation of macromolecule biosynthetic process regulation of DNA-directed DNA polymerase activity positive regulation of DNA-directed DNA polymerase activity positive regulation of cellular metabolic process positive regulation of biosynthetic process positive regulation of transferase activity positive regulation of DNA biosynthetic process regulation of DNA-templated DNA replication positive regulation of cellular biosynthetic process gland development animal organ regeneration liver development regeneration hepaticobiliary system development liver regeneration cellular response to oxidative stress cellular response to chemical stress cellular response to oxygen-containing compound cellular response to hydrogen peroxide response to reactive oxygen species response to hydrogen peroxide response to oxidative stress cellular response to reactive oxygen species response to light stimulus cellular response to radiation response to UV cellular response to environmental stimulus cellular response to light stimulus response to radiation response to abiotic stimulus cellular response to abiotic stimulus cellular response to UV base-excision repair, gap-filling base-excision repair response to metal ion response to cadmium ion response to estradiol	protein kinase complex transferase complex, transferring phosphorus-containing groups protein-containing complex catalytic complex serine/threonine protein kinase complex cyclin-dependent protein kinase holoenzyme complex transferase complex extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space protein kinase complex transferase complex, transferring phosphorus-containing groups protein-containing complex catalytic complex serine/threonine protein kinase complex cyclin-dependent protein kinase holoenzyme complex transferase complex extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space cellular anatomical entity vesicle extracellular membrane-bounded organelle intracellular organelle intracellular anatomical structure intracellular non-membrane-bounded organelle chromatin chromosome non-membrane-bounded organelle PCNA complex nucleus nuclear protein-containing complex intracellular membrane-bounded organelle enzyme activator complex DNA polymerase processivity factor complex male germ cell nucleus germ cell nucleus membrane-enclosed lumen nuclear replication fork nuclear chromosome intracellular organelle lumen organelle lumen replication fork nuclear lumen chromosome, telomeric region chromosomal region PCNA-p21 complex centrosome microtubule organizing center cytoskeleton microtubule cytoskeleton nucleoplasm nuclear periphery nuclear lamina nuclear body protein-DNA complex replisome
B, D, F	P21/WAF1	enzyme regulator activity enzyme inhibitor activity protein kinase regulator activity protein kinase inhibitor activity molecular function inhibitor activity cyclin-dependent protein serine/threonine kinase inhibitor activity molecular function regulator activity cyclin-dependent protein serine/threonine kinase regulator activity protein serine/threonine kinase inhibitor activity kinase inhibitor activity kinase regulator activity protein-containing complex binding binding catalytic activity, acting on a protein enzyme regulator activity enzyme inhibitor activity protein kinase regulator activity protein kinase inhibitor activity molecular function inhibitor activity cyclin-dependent protein serine/threonine kinase inhibitor activity molecular function regulator activity cyclin-dependent protein serine/threonine kinase regulator activity protein serine/threonine kinase inhibitor activity kinase inhibitor activity kinase regulator activity protein-containing complex binding binding catalytic activity, acting on a protein cyclin-dependent protein kinase activating kinase activity molecular function activator activity kinase activity protein kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor transferase activity, transferring phosphorus-containing groups kinase activator activity enzyme activator activity protein kinase activator activity catalytic activity ubiquitin protein ligase binding protein binding ubiquitin-like protein ligase binding enzyme binding cation binding ion binding metal ion binding small molecule binding molecular sequestering activity protein sequestering activity cyclin binding kinase binding protein kinase binding	cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process response to chemical response to xenobiotic stimulus developmental process heart development multicellular organism development multicellular organismal process anatomical structure development animal organ development cellular response to stimulus cellular response to stress response to stimulus DNA damage response response to stress cellular process response to chemical response to xenobiotic stimulus developmental process heart development multicellular organism development multicellular organismal process anatomical structure development animal organ development circulatory system development system development stress-induced premature senescence cellular metabolic process cellular senescence metabolic process regulation of protein binding regulation of molecular function negative regulation of protein binding negative regulation of binding regulation of binding biological regulation negative regulation of molecular function cellular response to heat response to heat response to abiotic stimulus response to temperature stimulus response to X-ray response to ionizing radiation response to radiation cellular developmental process cell development epithelial cell differentiation intestinal epithelial cell maturation columnar/cuboidal epithelial cell development cell differentiation cell maturation epithelium development digestive system development intestinal epithelial cell differentiation tube development intestinal epithelial cell development developmental maturation tissue development digestive tract development epithelial cell development anatomical structure maturation columnar/cuboidal epithelial cell differentiation epithelial cell maturation columnar/cuboidal epithelial cell maturation replicative senescence regulation of cellular process regulation of protein modification process regulation of protein phosphorylation negative regulation of biological process negative regulation of phosphate metabolic process negative regulation of cellular metabolic process regulation of primary metabolic process regulation of phosphate metabolic process phosphate-containing compound metabolic process negative regulation of protein modification process negative regulation of cellular process protein metabolic process protein modification process phosphorus metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biological process protein phosphorylation phosphorylation regulation of protein metabolic process negative regulation of metabolic process primary metabolic process regulation of cellular metabolic process regulation of macromolecule metabolic process negative regulation of protein phosphorylation macromolecule modification negative regulation of phosphorus metabolic process regulation of phosphorylation regulation of phosphorus metabolic process macromolecule metabolic process negative regulation of phosphorylation regulation of metabolic process positive regulation of nucleobase-containing compound metabolic process positive regulation of DNA replication positive regulation of biological process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process DNA replication positive regulation of DNA metabolic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of DNA metabolic process regulation of DNA replication tissue regeneration developmental growth growth regeneration cell population proliferation epithelial cell proliferation keratinocyte proliferation cellular response to ionizing radiation cellular response to radiation cellular response to abiotic stimulus cellular response to environmental stimulus regulation of growth regulation of cellular component organization negative regulation of cell growth regulation of cell growth cell growth cellular component organization negative regulation of growth cellular component organization or biogenesis protein localization establishment of protein localization cellular localization nitrogen compound transport nucleocytoplasmic transport transport nuclear transport intracellular transport protein localization to nucleus establishment of localization localization import into nucleus establishment of protein localization to organelle protein transport cellular macromolecule localization macromolecule localization protein localization to organelle establishment of localization in cell protein import into nucleus intracellular protein transport response to toxic substance regulation of cell cycle phase transition regulation of cell cycle process cell cycle phase transition regulation of cell cycle G1/S phase transition cell cycle G1/S phase transition cell cycle regulation of cell cycle cell cycle process embryo development ending in birth or egg hatching chordate embryonic development embryo development in utero embryonic development response to ketone response to lipid response to endogenous stimulus response to alcohol response to glucocorticoid response to oxygen-containing compound response to corticosterone response to mineralocorticoid response to corticosteroid response to hormone response to steroid hormone response to organic cyclic compound response to light stimulus response to UV response to UV-B cellular response to UV-B cellular response to light stimulus cellular response to UV fibroblast proliferation mitotic cell cycle process G1/S transition of mitotic cell cycle mitotic cell cycle mitotic cell cycle phase transition cell cycle G2/M phase transition regulation of G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle regulation of cell cycle G2/M phase transition regulation of mitotic cell cycle phase transition regulation of mitotic cell cycle response to aldosterone positive regulation of phosphorylation regulation of catalytic activity positive regulation of protein metabolic process positive regulation of cellular metabolic process regulation of transferase activity positive regulation of phosphate metabolic process positive regulation of molecular function positive regulation of protein modification process positive regulation of protein kinase activity positive regulation of protein phosphorylation positive regulation of cellular process positive regulation of transferase activity positive regulation of phosphorus metabolic process positive regulation of catalytic activity regulation of protein kinase activity positive regulation of kinase activity regulation of kinase activity positive regulation of cell population proliferation positive regulation of B cell proliferation regulation of leukocyte activation regulation of cell activation lymphocyte activation leukocyte proliferation leukocyte activation positive regulation of lymphocyte activation positive regulation of cell activation regulation of B cell proliferation lymphocyte proliferation regulation of B cell activation positive regulation of leukocyte activation positive regulation of mononuclear cell proliferation regulation of multicellular organismal process regulation of immune system process positive regulation of immune system process regulation of lymphocyte proliferation regulation of leukocyte proliferation B cell activation cell activation positive regulation of lymphocyte proliferation B cell proliferation positive regulation of B cell activation regulation of cell population proliferation mononuclear cell proliferation immune system process positive regulation of leukocyte proliferation regulation of mononuclear cell proliferation positive regulation of multicellular organismal process regulation of lymphocyte activation response to nutrient levels cellular response to amino acid starvation cellular response to starvation cellular response to nutrient levels response to amino acid starvation response to starvation regulation of cyclin-dependent protein kinase activity regulation of cyclin-dependent protein serine/threonine kinase activity regulation of protein serine/threonine kinase activity response to arsenic-containing substance regulation of vascular associated smooth muscle cell proliferation negative regulation of cell population proliferation regulation of smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell proliferation smooth muscle cell proliferation negative regulation of smooth muscle cell proliferation muscle cell proliferation vascular associated smooth muscle cell proliferation signaling DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator signal transduction by p53 class mediator DNA damage response, signal transduction by p53 class mediator intracellular signal transduction cell communication DNA damage response, signal transduction resulting in transcription signal transduction in response to DNA damage signal transduction negative regulation of catalytic activity negative regulation of kinase activity negative regulation of transferase activity negative regulation of cyclin-dependent protein kinase activity negative regulation of protein kinase activity epidermal cell differentiation epidermis development skin development keratinocyte differentiation cell death apoptotic signaling pathway apoptotic process intrinsic apoptotic signaling pathway programmed cell death cellular response to gamma radiation response to gamma radiation negative regulation of programmed cell death regulation of apoptotic process regulation of programmed cell death negative regulation of apoptotic process cellular biosynthetic process regulation of DNA biosynthetic process nucleic acid biosynthetic process negative regulation of nucleobase-containing compound metabolic process regulation of biosynthetic process nucleobase-containing compound biosynthetic process macromolecule biosynthetic process negative regulation of cellular biosynthetic process regulation of cellular biosynthetic process biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process negative regulation of DNA metabolic process regulation of macromolecule biosynthetic process DNA biosynthetic process negative regulation of DNA biosynthetic process regulation of fibroblast proliferation positive regulation of fibroblast proliferation cellular response to cell-matrix adhesion reactive oxygen species metabolic process positive regulation of reactive oxygen species metabolic process regulation of reactive oxygen species metabolic process small GTPase-mediated signal transduction Ras protein signal transduction intracellular signaling cassette oncogene-induced cell senescence DNA damage checkpoint signaling mitotic G2 DNA damage checkpoint signaling negative regulation of cell cycle negative regulation of mitotic cell cycle mitotic G2/M transition checkpoint mitotic DNA integrity checkpoint signaling mitotic DNA damage checkpoint signaling negative regulation of cell cycle phase transition negative regulation of mitotic cell cycle phase transition DNA integrity checkpoint signaling negative regulation of cell cycle process cell cycle checkpoint signaling mitotic cell cycle checkpoint signaling negative regulation of cell cycle G2/M phase transition negative regulation of G2/M transition of mitotic cell cycle regulation of developmental growth regulation of developmental process negative regulation of developmental process negative regulation of cardiac muscle tissue regeneration negative regulation of developmental growth cardiac muscle tissue regeneration regulation of cardiac muscle tissue regeneration negative regulation of G1/S transition of mitotic cell cycle negative regulation of cell cycle G1/S phase transition regulation of G1/S transition of mitotic cell cycle mitotic G1/S transition checkpoint signaling mitotic G1 DNA damage checkpoint signaling DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest wound healing response to wounding positive regulation of programmed cell death intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator intrinsic apoptotic signaling pathway by p53 class mediator intrinsic apoptotic signaling pathway in response to DNA damage animal organ regeneration gene expression regulation of gene expression negative regulation of gene expression response to oxygen levels response to hyperoxia response to increased oxygen levels	protein kinase complex transferase complex, transferring phosphorus-containing groups protein-containing complex catalytic complex serine/threonine protein kinase complex cyclin-dependent protein kinase holoenzyme complex transferase complex intracellular anatomical structure cytoplasm cellular anatomical entity cytosol perinuclear region of cytoplasm membrane-bounded organelle intracellular organelle protein kinase complex transferase complex, transferring phosphorus-containing groups protein-containing complex catalytic complex serine/threonine protein kinase complex cyclin-dependent protein kinase holoenzyme complex transferase complex intracellular anatomical structure cytoplasm cellular anatomical entity cytosol perinuclear region of cytoplasm membrane-bounded organelle intracellular organelle organelle nucleus nuclear protein-containing complex intracellular membrane-bounded organelle PCNA-p21 complex membrane-enclosed lumen nucleolus intracellular organelle lumen organelle lumen intracellular non-membrane-bounded organelle nuclear lumen non-membrane-bounded organelle nucleoplasm nuclear body

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C, E	IPR046938	DNA clamp superfamily	Homologous Superfamily
A, C, E	IPR022648	Proliferating cell nuclear antigen, PCNA, N-terminal	Domain
A, C, E	IPR000730	Proliferating cell nuclear antigen, PCNA	Family
A, C, E	IPR022649	Proliferating cell nuclear antigen, PCNA, C-terminal	Domain
A, C, E	IPR022659	Proliferating cell nuclear antigen, PCNA, conserved site	Conserved Site
B, D, F	IPR003175	Cyclin-dependent kinase inhibitor domain	Domain
B, D, F	IPR044898	Cyclin-dependent kinase inhibitor domain superfamily	Homologous Superfamily
B, D, F	IPR029841	Cyclin-dependent kinase inhibitor 1	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A, C, E	Pharos: P12004	psoriasis ataxia-telangiectasia-like disorder 2 hepatoblastoma adenocarcinoma malignant colon neoplasm granular cell carcinoma Radiation Injuries, Experimental tubular adenocarcinoma focal segmental glomerulosclerosis endometriosis pancreatic intraductal papillary-mucinous neoplasm glioblastoma primitive neuroectodermal tumor pustulosis palmaris et plantaris Sjogren syndrome psoriasis ataxia-telangiectasia-like disorder 2 hepatoblastoma adenocarcinoma malignant colon neoplasm granular cell carcinoma Radiation Injuries, Experimental tubular adenocarcinoma focal segmental glomerulosclerosis endometriosis pancreatic intraductal papillary-mucinous neoplasm glioblastoma primitive neuroectodermal tumor pustulosis palmaris et plantaris Sjogren syndrome large cell medulloblastoma astrocytic tumor lung cancer nasopharyngeal carcinoma colonic neoplasm neurodegenerative disease dermatomyositis ovarian cancer pituitary cancer IgA glomerulonephritis ischemic disease lung adenocarcinoma ataxia-telangiectasia-like disorder atypical teratoid rhabdoid tumor malignant glioma brain cancer medulloblastoma breast cancer cribriform carcinoma non-small cell lung carcinoma ductal breast carcinoma in situ pancreatic intraductal papillary-mucinous carcinoma invasive ductal breast carcinoma juvenile dermatomyositis lung benign neoplasm ataxia-telangiectasia-like disorder 1 lymphoplasmacytic lymphoma benign colon neoplasm myopathy breast carcinoma cribriform carcinoma of breast oligodendroglioma
B, D, F	Pharos: P38936	transitional cell carcinoma urinary bladder cancer esophageal squamous cell carcinoma malignant mesothelioma papilloma prostate cancer Hypertrophy kidney disease gastric cancer squamous papilloma intestinal cancer malignant colon neoplasm HIV infectious disease atrial fibrillation cancer transitional cell carcinoma urinary bladder cancer esophageal squamous cell carcinoma malignant mesothelioma papilloma prostate cancer Hypertrophy kidney disease gastric cancer squamous papilloma intestinal cancer malignant colon neoplasm HIV infectious disease atrial fibrillation cancer multiple endocrine neoplasia type 1 gastric neoplasm hereditary diffuse gastric adenocarcinoma abdominal aortic aneurysm benign colon neoplasm colonic neoplasm diabetic kidney disease Duchenne muscular dystrophy oligodendroglioma ovarian cancer papillomatosis glioblastoma tuberculosis ischemia reperfusion injury urinary bladder neoplasm astrocytic tumor large cell medulloblastoma breast disease lung benign neoplasm colorectal cancer myopathy ductal breast carcinoma in situ open-angle glaucoma eye disease pancreatic ductal adenocarcinoma gastric carcinoma pituitary cancer hematologic disease psoriasis subependymal giant cell astrocytoma intestinal neoplasm type 2 diabetes mellitus juvenile dermatomyositis limb-girdle muscular dystrophy lung cancer congestive heart failure dilated cardiomyopathy Emery-Dreifuss muscular dystrophy osteosarcoma facioscapulohumeral muscular dystrophy

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.