1DJY
PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-2,4,5-TRISPHOSPHATE
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | C2 domain (calcium/lipid-binding domain, calb) | 8040702 | 3000965 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | PLC-like phosphodiesterases | 8043839 | 3000615 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | PLC-like phosphodiesterases | 8043839 | 3000615 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | C2 domain (calcium/lipid-binding domain, calb) | 8040702 | 3000965 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | EF-hand | 8037376 | 3001983 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | C2 | e1djyA3 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: C2 domain (From Topology) | T: C2 domain | F: C2 | ECOD (1.6) |
A | EF-hand_like | e1djyA1 | A: alpha arrays | X: EF-hand | H: EF-hand-related | T: EF-hand | F: EF-hand_like | ECOD (1.6) |
A | PI-PLC-X | e1djyA2 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: PI-PLC-X | ECOD (1.6) |
B | C2 | e1djyB4 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: C2 domain (From Topology) | T: C2 domain | F: C2 | ECOD (1.6) |
B | EF-hand_10 | e1djyB1 | A: alpha arrays | X: EF-hand | H: EF-hand-related | T: EF-hand | F: EF-hand_10 | ECOD (1.6) |
B | EF-hand_like | e1djyB2 | A: alpha arrays | X: EF-hand | H: EF-hand-related | T: EF-hand | F: EF-hand_like | ECOD (1.6) |
B | PI-PLC-X | e1djyB3 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: PI-PLC-X | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.10.238.10 | Mainly Alpha | Orthogonal Bundle | Recoverin | domain 1 | CATH (4.3.0) |
A | 3.20.20.190 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Phosphatidylinositol (PI) phosphodiesterase | CATH (4.3.0) |
A | 2.60.40.150 | Mainly Beta | Sandwich | Immunoglobulin-like | C2 domain | CATH (4.3.0) |
B | 1.10.238.10 | Mainly Alpha | Orthogonal Bundle | Recoverin | domain 1 | CATH (4.3.0) |
B | 3.20.20.190 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Phosphatidylinositol (PI) phosphodiesterase | CATH (4.3.0) |
B | 2.60.40.150 | Mainly Beta | Sandwich | Immunoglobulin-like | C2 domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF09279 | Phosphoinositide-specific phospholipase C, efhand-like (EF-hand_like) | Phosphoinositide-specific phospholipase C, efhand-like | Members of this family are predominantly found in phosphoinositide-specific phospholipase C. They adopt a structure consisting of a core of four alpha helices, in an EF like fold, and are required for functioning of the enzyme [1]. | Domain | |
PF00387 | Phosphatidylinositol-specific phospholipase C, Y domain (PI-PLC-Y) | Phosphatidylinositol-specific phospholipase C, Y domain | - | Family | |
PF00168 | C2 domain (C2) | C2 domain | - | Domain | |
PF00388 | Phosphatidylinositol-specific phospholipase C, X domain (PI-PLC-X) | Phosphatidylinositol-specific phospholipase C, X domain | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR001849 | Pleckstrin homology domain | Domain | |
IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain | Domain | |
IPR000008 | C2 domain | Domain | |
IPR011993 | PH-like domain superfamily | Homologous Superfamily | |
IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain | Domain | |
IPR046975 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1, EF-hand domain | Domain | |
IPR002048 | EF-hand domain | Domain | |
IPR011992 | EF-hand domain pair | Homologous Superfamily | |
IPR018247 | EF-Hand 1, calcium-binding site | Binding Site | |
IPR015359 | Phosphoinositide-specific phospholipase C, EF-hand-like domain | Domain | |
IPR001192 | Phosphoinositide phospholipase C family | Family | |
IPR028391 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1, catalytic domain | Domain | |
IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily | Homologous Superfamily | |
IPR035892 | C2 domain superfamily | Homologous Superfamily |