1FD7

HEAT-LABILE ENTEROTOXIN B-PENTAMER WITH BOUND LIGAND BMSC001

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
J [auth P]	d1fd7p_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
A [auth D]	d1fd7d_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B [auth E]	d1fd7e_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
C [auth F]	d1fd7f_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
D [auth G]	d1fd7g_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
E [auth H]	d1fd7h_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
F [auth L]	d1fd7l_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
G [auth M]	d1fd7m_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
H [auth N]	d1fd7n_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
I [auth O]	d1fd7o_	All beta proteins	OB-fold	Bacterial enterotoxins	Bacterial AB5 toxins, B-subunits	Heat-labile toxin	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
J [auth P]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)
A [auth D]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)
B [auth E]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)
C [auth F]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)
D [auth G]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)
E [auth H]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)
F [auth L]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)
G [auth M]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)
H [auth N]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)
I [auth O]	SCOP2B Superfamily	Bacterial enterotoxins	8041780	3000434	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
J [auth P]	Enterotoxin_b	e1fd7P1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)
A [auth D]	Enterotoxin_b	e1fd7D1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)
B [auth E]	Enterotoxin_b	e1fd7E1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)
C [auth F]	Enterotoxin_b	e1fd7F1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)
D [auth G]	Enterotoxin_b	e1fd7G1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)
E [auth H]	Enterotoxin_b	e1fd7H1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)
F [auth L]	Enterotoxin_b	e1fd7L1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)
G [auth M]	Enterotoxin_b	e1fd7M1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)
H [auth N]	Enterotoxin_b	e1fd7N1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)
I [auth O]	Enterotoxin_b	e1fd7O1	A: beta barrels	X: OB-fold	H: Bacterial enterotoxins (From Topology)	T: Bacterial enterotoxins	F: Enterotoxin_b	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
J [auth P]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
A [auth D]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
B [auth E]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
C [auth F]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
D [auth G]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
E [auth H]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
F [auth L]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
G [auth M]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
H [auth N]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)
I [auth O]	2.40.50.110	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth L], G [auth M], H [auth N], I [auth O], J [auth P]	PF01376	Heat-labile enterotoxin beta chain (Enterotoxin_b)	Heat-labile enterotoxin beta chain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth L], G [auth M], H [auth N], I [auth O], J [auth P]	HEAT-LABILE ENTEROTOXIN B CHAIN	toxin activity	biological process involved in interspecies interaction between organisms cellular process disruption of cell in another organism disruption of anatomical structure in another organism killing of cells of another organism cell killing	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth L], G [auth M], H [auth N], I [auth O], J [auth P]	IPR001835	Heat-labile enterotoxin, B chain	Family
A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], A [auth D], B [auth E], C [auth F], D [auth G], E [auth H], F [auth L], G [auth M], H [auth N], I [auth O], J [auth P]	IPR008992	Enterotoxin	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.