Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
E [auth C]SCOP2B Superfamilybeta-beta-alpha zinc fingers 8038883 3001077 SCOP2B (2022-06-29)
E [auth C]SCOP2B Superfamilybeta-beta-alpha zinc fingers 8038885 3001077 SCOP2B (2022-06-29)
E [auth C]SCOP2B Superfamilybeta-beta-alpha zinc fingers 8038881 3001077 SCOP2B (2022-06-29)
FSCOP2B Superfamilybeta-beta-alpha zinc fingers 8038883 3001077 SCOP2B (2022-06-29)
FSCOP2B Superfamilybeta-beta-alpha zinc fingers 8038881 3001077 SCOP2B (2022-06-29)
FSCOP2B Superfamilybeta-beta-alpha zinc fingers 8038885 3001077 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
E [auth C]zf-C2H2_1e1g2fC1 A: few secondary structure elementsX: beta-beta-alpha zinc fingersH: beta-beta-alpha zinc fingers (From Topology)T: beta-beta-alpha zinc fingersF: zf-C2H2_1ECOD (1.6)
E [auth C]zf-C2H2_17e1g2fC2 A: few secondary structure elementsX: beta-beta-alpha zinc fingersH: beta-beta-alpha zinc fingers (From Topology)T: beta-beta-alpha zinc fingersF: zf-C2H2_17ECOD (1.6)
E [auth C]zf-C2H2_20e1g2fC3 A: few secondary structure elementsX: beta-beta-alpha zinc fingersH: beta-beta-alpha zinc fingers (From Topology)T: beta-beta-alpha zinc fingersF: zf-C2H2_20ECOD (1.6)
Fzf-C2H2_1e1g2fF1 A: few secondary structure elementsX: beta-beta-alpha zinc fingersH: beta-beta-alpha zinc fingers (From Topology)T: beta-beta-alpha zinc fingersF: zf-C2H2_1ECOD (1.6)
Fzf-C2H2_17e1g2fF2 A: few secondary structure elementsX: beta-beta-alpha zinc fingersH: beta-beta-alpha zinc fingers (From Topology)T: beta-beta-alpha zinc fingersF: zf-C2H2_17ECOD (1.6)
Fzf-C2H2_20e1g2fF3 A: few secondary structure elementsX: beta-beta-alpha zinc fingersH: beta-beta-alpha zinc fingers (From Topology)T: beta-beta-alpha zinc fingersF: zf-C2H2_20ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
E [auth C]3.30.160.60 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain Classic Zinc FingerCATH (4.3.0)
F3.30.160.60 Alpha Beta 2-Layer Sandwich Double Stranded RNA Binding Domain Classic Zinc FingerCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
E [auth C],
F
PF00096Zinc finger, C2H2 type (zf-C2H2)Zinc finger, C2H2 typeThe C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, an ...The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A,
C [auth D]
5'-D(*GP*AP*CP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*AP*G)-3'---
B,
D [auth E]
5'-D(*TP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*GP*TP*CP*C)-3'---
E [auth C],
F
TATA BOX ZINC FINGER PROTEIN