Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1gesa2 Alpha and beta proteins (a/b) FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain FAD/NAD-linked reductases, N-terminal and central domains Glutathione reductase, middle domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1gesa1 Alpha and beta proteins (a/b) FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain FAD/NAD-linked reductases, N-terminal and central domains Glutathione reductase, N- and C-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Ad1gesa3 Alpha and beta proteins (a+b) CO dehydrogenase flavoprotein C-domain-like FAD/NAD-linked reductases, dimerisation (C-terminal) domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain Glutathione reductase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1gesb2 Alpha and beta proteins (a/b) FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain FAD/NAD-linked reductases, N-terminal and central domains Glutathione reductase, middle domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1gesb1 Alpha and beta proteins (a/b) FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain FAD/NAD-linked reductases, N-terminal and central domains Glutathione reductase, N- and C-terminal domain (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)
Bd1gesb3 Alpha and beta proteins (a+b) CO dehydrogenase flavoprotein C-domain-like FAD/NAD-linked reductases, dimerisation (C-terminal) domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain Glutathione reductase (Escherichia coli ) [TaxId: 562 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyGSR C-terminal domain-like 8056212 3000028 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyThioredoxin reductase-like 8056211 3000050 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyThioredoxin reductase-like 8056211 3000050 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyGSR C-terminal domain-like 8056212 3000028 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APyr_redox_dime1gesA1 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
APyr_redox_2_1e1gesA3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
APyr_redox_2e1gesA2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
BPyr_redox_dime1gesB1 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
BPyr_redox_2_1e1gesB3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
BPyr_redox_2e1gesB2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.50.50.60 Alpha Beta 3-Layer(bba) Sandwich FAD/NAD(P)-binding domain FAD/NAD(P)-binding domainCATH (4.3.0)
A3.30.390.30 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)
B3.50.50.60 Alpha Beta 3-Layer(bba) Sandwich FAD/NAD(P)-binding domain FAD/NAD(P)-binding domainCATH (4.3.0)
B3.30.390.30 Alpha Beta 2-Layer Sandwich Enolase-like domain 1CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF00070Pyridine nucleotide-disulphide oxidoreductase (Pyr_redox)Pyridine nucleotide-disulphide oxidoreductaseThis family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.Domain
A, B
PF02852Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain (Pyr_redox_dim)Pyridine nucleotide-disulphide oxidoreductase, dimerisation domainThis family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
GLUTATHIONE REDUCTASE