Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1ja1a1 All beta proteins Reductase/isomerase/elongation factor common domain Riboflavin synthase domain-like NADPH-cytochrome p450 reductase FAD-binding domain-like NADPH-cytochrome p450 reductase Norway rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Ad1ja1a2 Alpha and beta proteins (a/b) Flavodoxin-like Flavoproteins Cytochrome p450 reductase N-terminal domain-like NADPH-cytochrome p450 reductase, N-terminal domain Norway rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Ad1ja1a3 Alpha and beta proteins (a/b) Ferredoxin reductase-like, C-terminal NADP-linked domain Ferredoxin reductase-like, C-terminal NADP-linked domain NADPH-cytochrome p450 reductase-like NADPH-cytochrome p450 reductase Norway rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Bd1ja1b1 All beta proteins Reductase/isomerase/elongation factor common domain Riboflavin synthase domain-like NADPH-cytochrome p450 reductase FAD-binding domain-like NADPH-cytochrome p450 reductase Norway rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Bd1ja1b2 Alpha and beta proteins (a/b) Flavodoxin-like Flavoproteins Cytochrome p450 reductase N-terminal domain-like NADPH-cytochrome p450 reductase, N-terminal domain Norway rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)
Bd1ja1b3 Alpha and beta proteins (a/b) Ferredoxin reductase-like, C-terminal NADP-linked domain Ferredoxin reductase-like, C-terminal NADP-linked domain NADPH-cytochrome p450 reductase-like NADPH-cytochrome p450 reductase Norway rat (Rattus norvegicus ) [TaxId: 10116 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyNADPH-cytochrome p450 reductase FAD-binding domain-like 8021876 4002074 SCOP2 (2022-06-29)
ASCOP2 FamilyCytochrome p450 reductase N-terminal domain-like 8021877 4003670 SCOP2 (2022-06-29)
ASCOP2 FamilyNADPH-cytochrome p450 reductase-like 8021879 4003798 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyRiboflavin synthase domain-like 8034256 3001812 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyFlavoproteins 8034257 3001217 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyFerredoxin reductase-like, C-terminal NADP-linked domain 8034259 3001461 SCOP2 (2022-06-29)
BSCOP2B SuperfamilyRiboflavin synthase domain-like 8034256 3001812 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyFlavoproteins 8034257 3001217 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyFerredoxin reductase-like, C-terminal NADP-linked domain 8034259 3001461 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AFAD_binding_1_1ste1ja1A4 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: FAD_binding_1_1stECOD (1.6)
AFAD_binding_1_2nde1ja1A5 A: alpha bundlesX: NADPH-cytochrome p450 reductase helical insertion domain (From Topology)H: NADPH-cytochrome p450 reductase helical insertion domain (From Topology)T: NADPH-cytochrome p450 reductase helical insertion domainF: FAD_binding_1_2ndECOD (1.6)
AFlavodoxin_1e1ja1A2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Flavoproteins/Phosphotyrosine protein phosphatases-likeT: FlavoproteinsF: Flavodoxin_1ECOD (1.6)
ANAD_binding_1e1ja1A3 A: a/b three-layered sandwichesX: Ferredoxin reductase-like, C-terminal NADP-linked domain (From Topology)H: Ferredoxin reductase-like, C-terminal NADP-linked domain (From Topology)T: Ferredoxin reductase-like, C-terminal NADP-linked domainF: NAD_binding_1ECOD (1.6)
BFAD_binding_1_1ste1ja1B5 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: FAD_binding_1_1stECOD (1.6)
BFAD_binding_1_2nde1ja1B4 A: alpha bundlesX: NADPH-cytochrome p450 reductase helical insertion domain (From Topology)H: NADPH-cytochrome p450 reductase helical insertion domain (From Topology)T: NADPH-cytochrome p450 reductase helical insertion domainF: FAD_binding_1_2ndECOD (1.6)
BFlavodoxin_1e1ja1B2 A: a/b three-layered sandwichesX: Flavodoxin-likeH: Flavoproteins/Phosphotyrosine protein phosphatases-likeT: FlavoproteinsF: Flavodoxin_1ECOD (1.6)
BNAD_binding_1e1ja1B3 A: a/b three-layered sandwichesX: Ferredoxin reductase-like, C-terminal NADP-linked domain (From Topology)H: Ferredoxin reductase-like, C-terminal NADP-linked domain (From Topology)T: Ferredoxin reductase-like, C-terminal NADP-linked domainF: NAD_binding_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF00667FAD binding domain (FAD_binding_1)FAD binding domainThis domain is found in sulfite reductase, NADPH cytochrome P450 reductase, Nitric oxide synthase and methionine synthase reductase.Domain
A, B
PF00175Oxidoreductase NAD-binding domain (NAD_binding_1)Oxidoreductase NAD-binding domainXanthine dehydrogenases, that also bind FAD/NAD, have essentially no similarity.Domain
A, B
PF00258Flavodoxin (Flavodoxin_1)Flavodoxin- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
NADPH-Cytochrome P450 Reductase