Annotations: 1K5J

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1k5ja_	All beta proteins	Nucleoplasmin-like/VP (viral coat and capsid proteins)	Nucleoplasmin-like core domain	Nucleoplasmin-like core domain	Nucleoplasmin core	African clawed frog (Xenopus laevis ) [TaxId: 8355 ],	SCOPe (2.08)
B	d1k5jb_	All beta proteins	Nucleoplasmin-like/VP (viral coat and capsid proteins)	Nucleoplasmin-like core domain	Nucleoplasmin-like core domain	Nucleoplasmin core	African clawed frog (Xenopus laevis ) [TaxId: 8355 ],	SCOPe (2.08)
C	d1k5jc_	All beta proteins	Nucleoplasmin-like/VP (viral coat and capsid proteins)	Nucleoplasmin-like core domain	Nucleoplasmin-like core domain	Nucleoplasmin core	African clawed frog (Xenopus laevis ) [TaxId: 8355 ],	SCOPe (2.08)
D	d1k5jd_	All beta proteins	Nucleoplasmin-like/VP (viral coat and capsid proteins)	Nucleoplasmin-like core domain	Nucleoplasmin-like core domain	Nucleoplasmin core	African clawed frog (Xenopus laevis ) [TaxId: 8355 ],	SCOPe (2.08)
E	d1k5je_	All beta proteins	Nucleoplasmin-like/VP (viral coat and capsid proteins)	Nucleoplasmin-like core domain	Nucleoplasmin-like core domain	Nucleoplasmin core	African clawed frog (Xenopus laevis ) [TaxId: 8355 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Nucleoplasmin-like core domain	8037830	3002011	SCOP2B (2022-06-29)
B	SCOP2 Family	Nucleoplasmin-like core domain	8025451	4003012	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Nucleoplasmin-like core domain	8037830	3002011	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	Nucleoplasmin-like core domain	8037830	3002011	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Nucleoplasmin-like core domain	8037830	3002011	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Nucleoplasmin-like core domain	8037830	3002011	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Nucleoplasmin	e1k5jA1	A: beta sandwiches	X: jelly-roll	H: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)	T: Nucleoplasmin-like/VP (viral coat and capsid proteins)	F: Nucleoplasmin	ECOD (1.6)
B	Nucleoplasmin	e1k5jB1	A: beta sandwiches	X: jelly-roll	H: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)	T: Nucleoplasmin-like/VP (viral coat and capsid proteins)	F: Nucleoplasmin	ECOD (1.6)
C	Nucleoplasmin	e1k5jC1	A: beta sandwiches	X: jelly-roll	H: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)	T: Nucleoplasmin-like/VP (viral coat and capsid proteins)	F: Nucleoplasmin	ECOD (1.6)
D	Nucleoplasmin	e1k5jD1	A: beta sandwiches	X: jelly-roll	H: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)	T: Nucleoplasmin-like/VP (viral coat and capsid proteins)	F: Nucleoplasmin	ECOD (1.6)
E	Nucleoplasmin	e1k5jE1	A: beta sandwiches	X: jelly-roll	H: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)	T: Nucleoplasmin-like/VP (viral coat and capsid proteins)	F: Nucleoplasmin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.120.340	Mainly Beta	Sandwich	Jelly Rolls	Nucleoplasmin core domain	CATH (4.3.0)
B	2.60.120.340	Mainly Beta	Sandwich	Jelly Rolls	Nucleoplasmin core domain	CATH (4.3.0)
C	2.60.120.340	Mainly Beta	Sandwich	Jelly Rolls	Nucleoplasmin core domain	CATH (4.3.0)
D	2.60.120.340	Mainly Beta	Sandwich	Jelly Rolls	Nucleoplasmin core domain	CATH (4.3.0)
E	2.60.120.340	Mainly Beta	Sandwich	Jelly Rolls	Nucleoplasmin core domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E	PF03066	Nucleoplasmin/nucleophosmin domain (Nucleoplasmin)	Nucleoplasmin/nucleophosmin domain	Nucleoplasmins are also known as chromatin decondensation proteins. They bind to core histones and transfer DNA to them in a reaction that requires ATP. This is thought to play a role in the assembly of regular nucleosomal arrays.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E	Nucleoplasmin Core	protein binding binding importin-alpha family protein binding protein carrier chaperone histone chaperone activity molecular carrier activity protein-containing complex binding chromatin binding nucleosome binding	organelle assembly sexual reproduction reproductive process fertilization sperm DNA decondensation cellular component organization cellular component biogenesis male pronucleus assembly organelle organization nucleus organization cellular component assembly chromatin organization cellular process cellular component organization or biogenesis organelle assembly sexual reproduction reproductive process fertilization sperm DNA decondensation cellular component organization cellular component biogenesis male pronucleus assembly organelle organization nucleus organization cellular component assembly chromatin organization cellular process cellular component organization or biogenesis single fertilization	membrane-bounded organelle intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membrane-bounded organelle cellular anatomical entity intracellular organelle lumen intracellular organelle nucleoplasm organelle lumen organelle nuclear lumen

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E	IPR004301	Nucleoplasmin family	Family
A, B, C, D, E	IPR024057	Nucleoplasmin core domain	Domain
A, B, C, D, E	IPR036824	Nucleoplasmin core domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.