Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
E [auth A]DNA_pol_A_2nde1lv5A1 A: alpha arraysX: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)H: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)T: helical bundle in Bacillus stearothermophilus-like DNA polymerase IF: DNA_pol_A_2ndECOD (1.6)
E [auth A]DNA_pol_A_1ste1lv5A2 A: alpha bundlesX: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)H: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)T: fingers domain in bacteriophage RB69-like DNA polymerase IF: DNA_pol_A_1stECOD (1.6)
E [auth A]DNA_pol_A_3rde1lv5A3 A: a+b two layersX: Alpha-beta plaitsH: Adenylyl and guanylyl cyclase catalytic domain-likeT: Adenylyl and guanylyl cyclase catalytic domain-likeF: DNA_pol_A_3rdECOD (1.6)
E [auth A]DNA_pol_A_exo1_1e1lv5A4 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: DNA_pol_A_exo1_1ECOD (1.6)
F [auth B]DNA_pol_A_2nde1lv5B1 A: alpha arraysX: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)H: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology)T: helical bundle in Bacillus stearothermophilus-like DNA polymerase IF: DNA_pol_A_2ndECOD (1.6)
F [auth B]DNA_pol_A_1ste1lv5B2 A: alpha bundlesX: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)H: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology)T: fingers domain in bacteriophage RB69-like DNA polymerase IF: DNA_pol_A_1stECOD (1.6)
F [auth B]DNA_pol_A_3rde1lv5B3 A: a+b two layersX: Alpha-beta plaitsH: Adenylyl and guanylyl cyclase catalytic domain-likeT: Adenylyl and guanylyl cyclase catalytic domain-likeF: DNA_pol_A_3rdECOD (1.6)
F [auth B]DNA_pol_A_exo1_1e1lv5B4 A: mixed a+b and a/bX: Ribonuclease H-likeH: Ribonuclease H-like (From Topology)T: Ribonuclease H-likeF: DNA_pol_A_exo1_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
E [auth A],
F [auth B]
PF22619DNA polymerase I, ribonuclease H-like domain (DNA_polI_exo1)DNA polymerase I, ribonuclease H-like domainThis domain is responsible for the 3'-5' exonuclease proofreading activity of E. coli DNA polymerase I (polI) and other related enzymes. It is one of the constituent domains of Klenow fragment.Domain
E [auth A],
F [auth B]
PF00476DNA polymerase family A (DNA_pol_A)DNA polymerase family A- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth C],
C [auth E]
5'-D(*GP*GP*AP*TP*CP*AP*GP*CP*GP*A)-3'---
B [auth D],
D [auth F]
5'-D(*AP*CP*GP*TP*CP*GP*CP*TP*GP*AP*TP*CP*CP*G)-3'---
E [auth A],
F [auth B]
DNA POLYMERASE I -