Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
A [auth C]d1n0vc1 All beta proteins Reductase/isomerase/elongation factor common domain Translation proteins Elongation factors Elongation factor 2 (eEF-2), domain II (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)
A [auth C]d1n0vc2 Alpha and beta proteins (a/b) P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases G proteins Elongation factor 2 (eEF-2), N-terminal (G) domain (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)
A [auth C]d1n0vc3 Alpha and beta proteins (a+b) Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like Translational machinery components Elongation factor 2 (eEF-2), domain IV (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)
A [auth C]d1n0vc5 Alpha and beta proteins (a+b) Ferredoxin-like EF-G C-terminal domain-like EF-G/eEF-2 domains III and V Elongation factor 2 (eEF-2), C-terminal domain (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)
A [auth C]d1n0vc4 Alpha and beta proteins (a+b) Ferredoxin-like EF-G C-terminal domain-like EF-G/eEF-2 domains III and V Elongation factor 2 (eEF-2), N-terminal domain (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)
B [auth D]d1n0vd1 All beta proteins Reductase/isomerase/elongation factor common domain Translation proteins Elongation factors Elongation factor 2 (eEF-2), domain II (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)
B [auth D]d1n0vd2 Alpha and beta proteins (a/b) P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases G proteins Elongation factor 2 (eEF-2), N-terminal (G) domain (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)
B [auth D]d1n0vd3 Alpha and beta proteins (a+b) Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like Translational machinery components Elongation factor 2 (eEF-2), domain IV (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)
B [auth D]d1n0vd5 Alpha and beta proteins (a+b) Ferredoxin-like EF-G C-terminal domain-like EF-G/eEF-2 domains III and V Elongation factor 2 (eEF-2), C-terminal domain (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)
B [auth D]d1n0vd4 Alpha and beta proteins (a+b) Ferredoxin-like EF-G C-terminal domain-like EF-G/eEF-2 domains III and V Elongation factor 2 (eEF-2), N-terminal domain (Saccharomyces cerevisiae ) [TaxId: 4932 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
A [auth C]SCOP2B SuperfamilyEF-G C-terminal domain-like 8043948 3001287 SCOP2B (2022-06-29)
A [auth C]SCOP2B SuperfamilyRibosomal protein S5 domain 2-like 8043947 3000100 SCOP2B (2022-06-29)
A [auth C]SCOP2B SuperfamilyRas-like P-loop GTPases 8043945 3002022 SCOP2B (2022-06-29)
A [auth C]SCOP2B SuperfamilyEF-G C-terminal domain-like 8043949 3001287 SCOP2B (2022-06-29)
A [auth C]SCOP2B SuperfamilyEF-Tu post-G domain-like 8043943 3002024 SCOP2B (2022-06-29)
B [auth D]SCOP2B SuperfamilyEF-G C-terminal domain-like 8043948 3001287 SCOP2B (2022-06-29)
B [auth D]SCOP2B SuperfamilyRibosomal protein S5 domain 2-like 8043947 3000100 SCOP2B (2022-06-29)
B [auth D]SCOP2B SuperfamilyRas-like P-loop GTPases 8043945 3002022 SCOP2B (2022-06-29)
B [auth D]SCOP2B SuperfamilyEF-Tu post-G domain-like 8043943 3002024 SCOP2B (2022-06-29)
B [auth D]SCOP2B SuperfamilyEF-G C-terminal domain-like 8043949 3001287 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth C]GTP_EFTU_D2e1n0vC1 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: GTP_EFTU_D2ECOD (1.6)
A [auth C]EFG_IVe1n0vC4 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: EFG_IVECOD (1.6)
A [auth C]EFG_Ce1n0vC3 A: a+b two layersX: Alpha-beta plaitsH: EF-G C-terminal domain-like (From Topology)T: EF-G C-terminal domain-likeF: EFG_CECOD (1.6)
A [auth C]EFG_IIe1n0vC2 A: a+b two layersX: Alpha-beta plaitsH: EF-G C-terminal domain-like (From Topology)T: EF-G C-terminal domain-likeF: EFG_IIECOD (1.6)
A [auth C]MnmE_helical_2nde1n0vC5 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: MnmE_helical_2ndECOD (1.6)
B [auth D]GTP_EFTU_D2e1n0vD1 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: GTP_EFTU_D2ECOD (1.6)
B [auth D]EFG_IVe1n0vD4 A: a+b two layersX: Ribosomal protein S5 domain 2-like (From Topology)H: Ribosomal protein S5 domain 2-like (From Topology)T: Ribosomal protein S5 domain 2-likeF: EFG_IVECOD (1.6)
B [auth D]EFG_Ce1n0vD3 A: a+b two layersX: Alpha-beta plaitsH: EF-G C-terminal domain-like (From Topology)T: EF-G C-terminal domain-likeF: EFG_CECOD (1.6)
B [auth D]EFG_IIe1n0vD2 A: a+b two layersX: Alpha-beta plaitsH: EF-G C-terminal domain-like (From Topology)T: EF-G C-terminal domain-likeF: EFG_IIECOD (1.6)
B [auth D]MnmE_helical_2nde1n0vD5 A: a/b three-layered sandwichesX: P-loop domains-likeH: P-loop domains-relatedT: P-loop containing nucleoside triphosphate hydrolasesF: MnmE_helical_2ndECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth C],
B [auth D]
PF00679Elongation factor G C-terminus (EFG_C)Elongation factor G C-terminusThis domain includes the carboxyl terminal regions of Elongation factor G, elongation factor 2 and some tetracycline resistance proteins and adopt a ferredoxin-like fold.Domain
A [auth C],
B [auth D]
PF00009Elongation factor Tu GTP binding domain (GTP_EFTU)Elongation factor Tu GTP binding domainThis domain contains a P-loop motif, also found in several other families such as Pfam:PF00071, Pfam:PF00025 and Pfam:PF00063. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains.Domain
A [auth C],
B [auth D]
PF14492Elongation Factor G, domain III (EFG_III)Elongation Factor G, domain IIIThis domain is found in Elongation Factor G. It shares a similar structure with domain V (Pfam:PF00679). Structural studies in drosophila indicate this is domain 3 [1].Domain
A [auth C],
B [auth D]
PF03144Elongation factor Tu domain 2 (GTP_EFTU_D2)Elongation factor Tu domain 2Elongation factor Tu consists of three structural domains, this is the second domain. This domain adopts a beta barrel structure. This the second domain is involved in binding to charged tRNA [1]. This domain is also found in other proteins such as e ...Elongation factor Tu consists of three structural domains, this is the second domain. This domain adopts a beta barrel structure. This the second domain is involved in binding to charged tRNA [1]. This domain is also found in other proteins such as elongation factor G and translation initiation factor IF-2. This domain is structurally related to Pfam:PF03143, and in fact has weak sequence matches to this domain.
Domain
A [auth C],
B [auth D]
PF03764Elongation factor G, domain IV (EFG_IV)Elongation factor G, domain IVThis domain is found in elongation factor G, elongation factor 2 and some tetracycline resistance proteins and adopts a ribosomal protein S5 domain 2-like fold.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth C],
B [auth D]
Elongation factor 2