1N1D

Glycerol-3-phosphate cytidylyltransferase complexed with CDP-glycerol

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Structure Motif: Primary M-CSA Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1n1da_	Alpha and beta proteins (a/b)	Adenine nucleotide alpha hydrolase-like	Nucleotidylyl transferase	Cytidylyltransferase	CTP:glycerol-3-phosphate cytidylyltransferase	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
B	d1n1db_	Alpha and beta proteins (a/b)	Adenine nucleotide alpha hydrolase-like	Nucleotidylyl transferase	Cytidylyltransferase	CTP:glycerol-3-phosphate cytidylyltransferase	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
C	d1n1dc_	Alpha and beta proteins (a/b)	Adenine nucleotide alpha hydrolase-like	Nucleotidylyl transferase	Cytidylyltransferase	CTP:glycerol-3-phosphate cytidylyltransferase	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
D	d1n1dd_	Alpha and beta proteins (a/b)	Adenine nucleotide alpha hydrolase-like	Nucleotidylyl transferase	Cytidylyltransferase	CTP:glycerol-3-phosphate cytidylyltransferase	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Nucleotidylyl transferase	8044207	3001541	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Nucleotidylyl transferase	8044207	3001541	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Nucleotidylyl transferase	8044207	3001541	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Nucleotidylyl transferase	8044207	3001541	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CTP_transf_like_1	e1n1dA1	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: CTP_transf_like_1	ECOD (1.6)
B	CTP_transf_like_1	e1n1dB1	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: CTP_transf_like_1	ECOD (1.6)
C	CTP_transf_like_1	e1n1dC1	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: CTP_transf_like_1	ECOD (1.6)
D	CTP_transf_like_1	e1n1dD1	A: a/b three-layered sandwiches	X: HUP domain-like	H: HUP domains (From Topology)	T: HUP domains	F: CTP_transf_like_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.620	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HUPs	CATH (4.3.0)
B	3.40.50.620	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HUPs	CATH (4.3.0)
C	3.40.50.620	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HUPs	CATH (4.3.0)
D	3.40.50.620	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	HUPs	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF01467	Cytidylyltransferase-like (CTP_transf_like)	Cytidylyltransferase-like	This family includes: Cholinephosphate cytidylyltransferase Swiss:P49585; glycerol-3-phosphate cytidylyltransferase Swiss:P27623. It also includes putative adenylyltransferases, and FAD synthases.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	glycerol-3-phosphate cytidylyltransferase	cytidylyltransferase activity glycerol-3-phosphate cytidylyltransferase activity transferase activity nucleotidyltransferase activity catalytic activity transferase activity, transferring phosphorus-containing groups cation binding ion binding binding metal ion binding small molecule binding	carbohydrate derivative biosynthetic process teichoic acid biosynthetic process peptidoglycan-based cell wall biogenesis small molecule biosynthetic process cell wall organization or biogenesis carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process macromolecule biosynthetic process cellular component biogenesis cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process cellular process carbohydrate derivative biosynthetic process teichoic acid biosynthetic process peptidoglycan-based cell wall biogenesis small molecule biosynthetic process cell wall organization or biogenesis carbohydrate derivative metabolic process organic acid biosynthetic process organic acid metabolic process macromolecule biosynthetic process cellular component biogenesis cell wall biogenesis biosynthetic process cell wall macromolecule biosynthetic process cellular process metabolic process small molecule metabolic process cellular component organization or biogenesis macromolecule metabolic process teichoic acid metabolic process cellular component organization cell wall organization external encapsulating structure organization	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR006409	Glycerol-3-phosphate cytidylyltransferase	Family
A, B, C, D	IPR004821	Cytidyltransferase-like domain	Domain
A, B, C, D	IPR050385	Archaeal FAD synthase	Family
A, B, C, D	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold	Homologous Superfamily

Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage

Chains	Enzyme Name	Description	Catalytic Residues
A	glycerol-3-phosphate cytidylyltransferase M-CSA #296	Glycerol-3-phosphate cytidylyltransferase catalyses the transfer of the cytidylyl group of CTP to sn-glycerol 3-phosphate so the activated glycerol 3-phosphate can be used for the biosynthesis of teichoic acid linkage units in bacterial cell walls.	Defined by 2 residues: LYS:A-44LYS:A-46 \| Explore in 3D: M-CSA Motif Definition Search M-CSA Motif EC: 2.7.7.39 (PDB Primary Data) Search M-CSA Motif + EC 2.7.7.39

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.