1NSZ

Crystal structure of galactose mutarotase from Lactococcus lactis mutant H170N complexed with glucose

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1nsza1	All beta proteins	Supersandwich	Galactose mutarotase-like	Aldose 1-epimerase (mutarotase)	Galactose mutarotase	(Lactococcus lactis ) [TaxId: 1358 ],	SCOPe (2.08)
A	d1nsza3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Lactococcus lactis ) [TaxId: 1358 ],	SCOPe (2.08)
A	d1nsza2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Lactococcus lactis ) [TaxId: 1358 ],	SCOPe (2.08)
B	d1nszb1	All beta proteins	Supersandwich	Galactose mutarotase-like	Aldose 1-epimerase (mutarotase)	Galactose mutarotase	(Lactococcus lactis ) [TaxId: 1358 ],	SCOPe (2.08)
B	d1nszb3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Lactococcus lactis ) [TaxId: 1358 ],	SCOPe (2.08)
B	d1nszb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Lactococcus lactis ) [TaxId: 1358 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Aldose 1-epimerase (mutarotase)	8002392	4000040	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Galactose mutarotase-like	8057614	3000035	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Galactose mutarotase-like	8057614	3000035	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Aldose_epim	e1nszA1	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: supersandwich (From Topology)	T: supersandwich	F: Aldose_epim	ECOD (1.6)
B	Aldose_epim	e1nszB1	A: beta sandwiches	X: Glycosyl hydrolase domain-like	H: supersandwich (From Topology)	T: supersandwich	F: Aldose_epim	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.70.98.10	Mainly Beta	Distorted Sandwich	Beta-galactosidase	Chain A, domain 5	CATH (4.3.0)
B	2.70.98.10	Mainly Beta	Distorted Sandwich	Beta-galactosidase	Chain A, domain 5	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01263	Aldose 1-epimerase (Aldose_epim)	Aldose 1-epimerase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	GALACTOSE MUTAROTASE	isomerase activity aldose 1-epimerase activity racemase and epimerase activity racemase and epimerase activity, acting on carbohydrates and derivatives catalytic activity binding carbohydrate binding	monosaccharide metabolic process carbohydrate metabolic process catabolic process hexose catabolic process carbohydrate catabolic process galactose catabolic process hexose metabolic process primary metabolic process galactose metabolic process galactose catabolic process via UDP-galactose small molecule metabolic process metabolic process cellular process monosaccharide catabolic process monosaccharide metabolic process carbohydrate metabolic process catabolic process hexose catabolic process carbohydrate catabolic process galactose catabolic process hexose metabolic process primary metabolic process galactose metabolic process galactose catabolic process via UDP-galactose small molecule metabolic process metabolic process cellular process monosaccharide catabolic process small molecule catabolic process glucose metabolic process	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR013458	Aldose 1-epimerase, bacterial	Family
A, B	IPR047215	Galactose mutarotase-like	Family
A, B	IPR015443	Aldose 1-epimerase	Family
A, B	IPR014718	Glycoside hydrolase-type carbohydrate-binding	Homologous Superfamily
A, B	IPR008183	Aldose 1-/Glucose-6-phosphate 1-epimerase	Family
A, B	IPR011013	Galactose mutarotase-like domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.