Annotations: 1OUU

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1ouua_	All alpha proteins	Globin-like	Globin-like	Globins	Hemoglobin, alpha-chain	rainbow trout (Oncorhynchus mykiss ) [TaxId: 8022 ],	SCOPe (2.08)
C	d1ouuc_	All alpha proteins	Globin-like	Globin-like	Globins	Hemoglobin, alpha-chain	rainbow trout (Oncorhynchus mykiss ) [TaxId: 8022 ],	SCOPe (2.08)
B	d1ouub_	All alpha proteins	Globin-like	Globin-like	Globins	Hemoglobin, beta-chain	rainbow trout (Oncorhynchus mykiss ) [TaxId: 8022 ],	SCOPe (2.08)
D	d1ouud_	All alpha proteins	Globin-like	Globin-like	Globins	Hemoglobin, beta-chain	rainbow trout (Oncorhynchus mykiss ) [TaxId: 8022 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Globin-like	8036045	3000554	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Globin-like	8036045	3000554	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Globin-like	8036214	3000554	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Globin-like	8036214	3000554	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Globin	e1ouuA1	A: alpha arrays	X: Globin-like (From Topology)	H: Globin-like (From Topology)	T: Globin-like	F: Globin	ECOD (1.6)
C	Globin	e1ouuC1	A: alpha arrays	X: Globin-like (From Topology)	H: Globin-like (From Topology)	T: Globin-like	F: Globin	ECOD (1.6)
B	Globin	e1ouuB1	A: alpha arrays	X: Globin-like (From Topology)	H: Globin-like (From Topology)	T: Globin-like	F: Globin	ECOD (1.6)
D	Globin	e1ouuD1	A: alpha arrays	X: Globin-like (From Topology)	H: Globin-like (From Topology)	T: Globin-like	F: Globin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.490.10	Mainly Alpha	Orthogonal Bundle	Globin-like	Globins	CATH (4.3.0)
C	1.10.490.10	Mainly Alpha	Orthogonal Bundle	Globin-like	Globins	CATH (4.3.0)
B	1.10.490.10	Mainly Alpha	Orthogonal Bundle	Globin-like	Globins	CATH (4.3.0)
D	1.10.490.10	Mainly Alpha	Orthogonal Bundle	Globin-like	Globins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF00042	Globin (Globin)	Globin	-	Domain
B, D	PF00042	Globin (Globin)	Globin	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	HEMOGLOBIN I	oxygen binding binding small molecule binding oxygen carrier activity molecular carrier activity organic cyclic compound binding tetrapyrrole binding heme binding cation binding ion binding metal ion binding	-	protein-containing complex cellular anatomical structure intracellular anatomical structure hemoglobin complex cytoplasm cytosol
B, D	HEMOGLOBIN I	protein binding binding haptoglobin binding oxygen binding small molecule binding oxygen carrier activity molecular carrier activity peroxidase activity oxidoreductase activity antioxidant activity oxidoreductase activity, acting on peroxide as acceptor catalytic activity organic cyclic compound binding tetrapyrrole binding protein binding binding haptoglobin binding oxygen binding small molecule binding oxygen carrier activity molecular carrier activity peroxidase activity oxidoreductase activity antioxidant activity oxidoreductase activity, acting on peroxide as acceptor catalytic activity organic cyclic compound binding tetrapyrrole binding heme binding organic acid binding cation binding ion binding metal ion binding	catabolic process hydrogen peroxide metabolic process reactive oxygen species metabolic process metabolic process cellular process hydrogen peroxide catabolic process	protein-containing complex cellular anatomical structure intracellular anatomical structure hemoglobin complex cytoplasm cytosol haptoglobin-hemoglobin complex extracellular region extracellular space blood microparticle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR050056	Hemoglobin and related oxygen transporters	Family
A, C	IPR002338	Hemoglobin, alpha-type	Family
A, C	IPR009050	Globin-like superfamily	Homologous Superfamily
A, C	IPR000971	Globin	Domain
A, C	IPR012292	Globin/Protoglobin	Homologous Superfamily
B, D	IPR050056	Hemoglobin and related oxygen transporters	Family
B, D	IPR009050	Globin-like superfamily	Homologous Superfamily
B, D	IPR012292	Globin/Protoglobin	Homologous Superfamily
B, D	IPR002337	Hemoglobin, beta-type	Family
B, D	IPR000971	Globin	Domain

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, C	ACE	RESID: AA0041 , AA0042 , AA0043 , AA0044 , AA0045 , AA0046 , AA0049 , AA0050 , AA0051 , AA0052 , AA0053 , AA0054 , AA0354 PSI-MOD : N-acetyl-L-alanine MOD:00050 , N-acetyl-L-aspartic acid MOD:00051 , N-acetyl-L-cysteine MOD:00052 , N-acetyl-S-archeol-cysteine MOD:00897 , N-acetyl-L-glutamic acid MOD:00053 , N-acetyl-L-glutamine MOD:00054 , N-acetylglycine MOD:00055 , N-acetyl-L-methionine MOD:00058 , N-acetyl-L-proline MOD:00059 , N-acetyl-L-serine MOD:00060 , N,O-diacetylated L-serine MOD:00648 , N-acetyl-L-threonine MOD:00061 , N-acetyl-L-tyrosine MOD:00062 , N-acetyl-L-valine MOD:00063 , N2-acetyl-L-arginine MOD:00359

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.