1PVS
3-methyladenine Glcosylase II(AlkA) Hypoxanthine complex
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d1pvsa1 | All alpha proteins | DNA-glycosylase | DNA-glycosylase | DNA repair glycosylase, 2 C-terminal domains | 3-Methyladenine DNA glycosylase II (gene alkA or aidA) | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
A | d1pvsa2 | Alpha and beta proteins (a+b) | TBP-like | TATA-box binding protein-like | DNA repair glycosylase, N-terminal domain | 3-Methyladenine DNA glycosylase II (gene alkA or aidA) | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
B | d1pvsb1 | All alpha proteins | DNA-glycosylase | DNA-glycosylase | DNA repair glycosylase, 2 C-terminal domains | 3-Methyladenine DNA glycosylase II (gene alkA or aidA) | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
B | d1pvsb2 | Alpha and beta proteins (a+b) | TBP-like | TATA-box binding protein-like | DNA repair glycosylase, N-terminal domain | 3-Methyladenine DNA glycosylase II (gene alkA or aidA) | (Escherichia coli ) [TaxId: 562 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | TATA-box binding protein-like | 8036364 | 3000705 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | DNA-glycosylase | 8038321 | 3000905 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | DNA-glycosylase | 8038321 | 3000905 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | TATA-box binding protein-like | 8036364 | 3000705 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | HhH-GPD | e1pvsA1 | A: alpha arrays | X: HhH/H2TH | H: SAM/DNA-glycosylase | T: DNA-glycosylase | F: HhH-GPD | ECOD (1.6) |
A | AlkA_N | e1pvsA2 | A: a+b two layers | X: TBP-like | H: TATA-box binding protein-like (From Topology) | T: TATA-box binding protein-like | F: AlkA_N | ECOD (1.6) |
B | HhH-GPD | e1pvsB1 | A: alpha arrays | X: HhH/H2TH | H: SAM/DNA-glycosylase | T: DNA-glycosylase | F: HhH-GPD | ECOD (1.6) |
B | AlkA_N | e1pvsB2 | A: a+b two layers | X: TBP-like | H: TATA-box binding protein-like (From Topology) | T: TATA-box binding protein-like | F: AlkA_N | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.30.310.20 | Alpha Beta | 2-Layer Sandwich | TATA-Binding Protein | DNA-3-methyladenine glycosylase AlkA, N-terminal domain | CATH (4.3.0) |
A | 1.10.340.30 | Mainly Alpha | Orthogonal Bundle | Endonuclease III | domain 1 | CATH (4.3.0) |
A | 1.10.1670.10 | Mainly Alpha | Orthogonal Bundle | Endonuclease Iii, domain 2 | Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) | CATH (4.3.0) |
B | 3.30.310.20 | Alpha Beta | 2-Layer Sandwich | TATA-Binding Protein | DNA-3-methyladenine glycosylase AlkA, N-terminal domain | CATH (4.3.0) |
B | 1.10.340.30 | Mainly Alpha | Orthogonal Bundle | Endonuclease III | domain 1 | CATH (4.3.0) |
B | 1.10.1670.10 | Mainly Alpha | Orthogonal Bundle | Endonuclease Iii, domain 2 | Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF06029 | AlkA N-terminal domain (AlkA_N) | AlkA N-terminal domain | - | Domain | |
PF00730 | HhH-GPD superfamily base excision DNA repair protein (HhH-GPD) | HhH-GPD superfamily base excision DNA repair protein | This family contains a diverse range of structurally related DNA repair proteins. The superfamily is called the HhH-GPD family after its hallmark Helix-hairpin-helix and Gly/Pro rich loop followed by a conserved aspartate [2]. This includes endonucle ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR000035 | Alkylbase DNA glycosidase, conserved site | Conserved Site | |
IPR003265 | HhH-GPD domain | Domain | |
IPR023170 | Helix-hairpin-helix, base-excision DNA repair, C-terminal | Homologous Superfamily | |
IPR037046 | DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily | Homologous Superfamily | |
IPR051912 | Alkylbase DNA Glycosylase/Transcriptional Activator | Family | |
IPR010316 | DNA-3-methyladenine glycosylase AlkA, N-terminal | Domain | |
IPR011257 | DNA glycosylase | Homologous Superfamily |