Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1wdka1 All alpha proteins 6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like HCDH C-domain-like Fatty oxidation complex alpha subunit, C-terminal domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)
Ad1wdka3 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase-like, N-terminal domain Fatty oxidation complex alpha subunit, middle domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)
Ad1wdka4 Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase Crotonase-like Fatty oxidation complex alpha subunit, N-terminal domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)
Bd1wdkb1 All alpha proteins 6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like HCDH C-domain-like Fatty oxidation complex alpha subunit, C-terminal domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)
Bd1wdkb3 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase-like, N-terminal domain Fatty oxidation complex alpha subunit, middle domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)
Bd1wdkb4 Alpha and beta proteins (a/b) ClpP/crotonase ClpP/crotonase Crotonase-like Fatty oxidation complex alpha subunit, N-terminal domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)
Cd1wdkc2 Alpha and beta proteins (a/b) Thiolase-like Thiolase-like Thiolase-related Fatty oxidation complex beta subunit (3-ketoacyl-CoA thiolase), C-terminal domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)
Cd1wdkc1 Alpha and beta proteins (a/b) Thiolase-like Thiolase-like Thiolase-related Fatty oxidation complex beta subunit (3-ketoacyl-CoA thiolase), N-terminal domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)
Dd1wdkd2 Alpha and beta proteins (a/b) Thiolase-like Thiolase-like Thiolase-related Fatty oxidation complex beta subunit (3-ketoacyl-CoA thiolase), C-terminal domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)
Dd1wdkd1 Alpha and beta proteins (a/b) Thiolase-like Thiolase-like Thiolase-related Fatty oxidation complex beta subunit (3-ketoacyl-CoA thiolase), N-terminal domain (Pseudomonas fragi ) [TaxId: 296 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyCrotonase-like 8001140 4000036 SCOP2 (2022-06-29)
ASCOP2 FamilyL-3-hydroxyacyl CoA dehydrogenase (HCDH)-like 8001143 4000107 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyClpP/crotonase 8001546 3000033 SCOP2 (2022-06-29)
ASCOP2 Superfamily6-phosphogluconate dehydrogenase-like 8017508 3000048 SCOP2 (2022-06-29)
BSCOP2B Superfamily6-phosphogluconate dehydrogenase-like 8017508 3000048 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyClpP/crotonase 8001546 3000033 SCOP2B (2022-06-29)
CSCOP2 FamilyThiolase-related 8029327 4000245 SCOP2 (2022-06-29)
CSCOP2 FamilyThiolase-related 8029329 4000245 SCOP2 (2022-06-29)
CSCOP2 SuperfamilyThiolase-like 8041706 3000122 SCOP2 (2022-06-29)
CSCOP2 SuperfamilyThiolase-like 8041708 3000122 SCOP2 (2022-06-29)
DSCOP2B SuperfamilyThiolase-like 8041706 3000122 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyThiolase-like 8041708 3000122 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A3HCDHe1wdkA1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: 3HCDHECOD (1.6)
A3HCDH_Ne1wdkA3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: 3HCDH_NECOD (1.6)
AECH_1e1wdkA4 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: ECH_1ECOD (1.6)
B3HCDHe1wdkB1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: 3HCDHECOD (1.6)
B3HCDH_Ne1wdkB3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: 3HCDH_NECOD (1.6)
BECH_1e1wdkB4 A: a/b three-layered sandwichesX: ClpP/crotonase (From Topology)H: ClpP/crotonase (From Topology)T: ClpP/crotonaseF: ECH_1ECOD (1.6)
CThiolase_Ce1wdkC1 A: a/b three-layered sandwichesX: Thiolase-like (From Topology)H: Thiolase-like (From Topology)T: Thiolase-likeF: Thiolase_CECOD (1.6)
CThiolase_Ne1wdkC2 A: a/b three-layered sandwichesX: Thiolase-like (From Topology)H: Thiolase-like (From Topology)T: Thiolase-likeF: Thiolase_NECOD (1.6)
DThiolase_Ce1wdkD1 A: a/b three-layered sandwichesX: Thiolase-like (From Topology)H: Thiolase-like (From Topology)T: Thiolase-likeF: Thiolase_CECOD (1.6)
DThiolase_Ne1wdkD2 A: a/b three-layered sandwichesX: Thiolase-like (From Topology)H: Thiolase-like (From Topology)T: Thiolase-likeF: Thiolase_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF027373-hydroxyacyl-CoA dehydrogenase, NAD binding domain (3HCDH_N)3-hydroxyacyl-CoA dehydrogenase, NAD binding domainThis family also includes lambda crystallin.Domain
A, B
PF007253-hydroxyacyl-CoA dehydrogenase, C-terminal domain (3HCDH)3-hydroxyacyl-CoA dehydrogenase, C-terminal domainThis family also includes lambda crystallin. Some proteins include two copies of this domain.Domain
A, B
PF00378Enoyl-CoA hydratase/isomerase (ECH_1)Enoyl-CoA hydratase/isomeraseThis family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.Domain
C, D
PF02803Thiolase, C-terminal domain (Thiolase_C)Thiolase, C-terminal domainThiolase is reported to be structurally related to beta-ketoacyl synthase (Pfam:PF00109), and also chalcone synthase.Domain
C, D
PF00108Thiolase, N-terminal domain (Thiolase_N)Thiolase, N-terminal domainThiolase is reported to be structurally related to beta-ketoacyl synthase (Pfam:PF00109), and also chalcone synthase.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Fatty oxidation complex alpha subunit
C, D
3-ketoacyl-CoA thiolase