Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
A [auth X]SCOP2B SuperfamilyNuclear receptor ligand-binding domain 8035649 3001442 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth X]Hormone_recep_1e1wm0X1 A: alpha arraysX: Nuclear receptor ligand-binding domain (From Topology)H: Nuclear receptor ligand-binding domain (From Topology)T: Nuclear receptor ligand-binding domainF: Hormone_recep_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A [auth X]1.10.565.10 Mainly Alpha Orthogonal Bundle Retinoid X Receptor Retinoid X ReceptorCATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth X]Peroxisome proliferator activated receptor gamma
B [auth Y]14-mer from Nuclear receptor coactivator 2

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A [auth X]IPR001628Zinc finger, nuclear hormone receptor-typeDomain
A [auth X]IPR013088Zinc finger, NHR/GATA-typeHomologous Superfamily
A [auth X]IPR001723Nuclear hormone receptorFamily
A [auth X]IPR003077Peroxisome proliferator-activated receptor gammaFamily
A [auth X]IPR000536Nuclear hormone receptor, ligand-binding domainDomain
A [auth X]IPR003074Peroxisome proliferator-activated receptorFamily
A [auth X]IPR050234Nuclear hormone receptor family NR1 subfamilyFamily
A [auth X]IPR022590Peroxisome proliferator-activated receptor gamma, N-terminalDomain
A [auth X]IPR035500Nuclear hormone receptor-like domain superfamilyHomologous Superfamily
B [auth Y]IPR010011Nuclear receptor coactivator, DUF1518Domain
B [auth Y]IPR009110Nuclear receptor coactivator, interlockingHomologous Superfamily
B [auth Y]IPR017426Nuclear receptor coactivatorFamily
B [auth Y]IPR014935Nuclear receptor coactivator, receptor-binding domainDomain
B [auth Y]IPR014920Nuclear receptor coactivator, Ncoa-type, interlockingDomain
B [auth Y]IPR035965PAS domain superfamilyHomologous Superfamily
B [auth Y]IPR028822Nuclear receptor coactivator 2, basic helix-loop-helixDomain
B [auth Y]IPR036638Helix-loop-helix DNA-binding domain superfamilyHomologous Superfamily
B [auth Y]IPR037077Nuclear receptor coactivator, Ncoa-type, interlocking domain superfamilyHomologous Superfamily
B [auth Y]IPR013767PAS foldDomain
B [auth Y]IPR000014PAS domainDomain
B [auth Y]IPR011598Myc-type, basic helix-loop-helix (bHLH) domainDomain
B [auth Y]IPR032565Nuclear receptor coactivator 2/3, DUF4927Domain

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A [auth X]PharosP37231