1YNP

aldo-keto reductase AKR11C1 from Bacillus halodurans (apo form)

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d1ynpb1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	NAD(P)-linked oxidoreductase	automated matches	automated matches	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
B	d1ynpb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
A	d1ynpa1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	NAD(P)-linked oxidoreductase	automated matches	automated matches	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)
A	d1ynpa2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Halalkalibacterium halodurans C-125 ) [TaxId: 272558 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	NAD(P)-linked oxidoreductase	8075511	3000288	SCOP2B (2022-06-29)
A	SCOP2 Family	Aldo-keto reductases (NADP)	8075510	4003124	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	NAD(P)-linked oxidoreductase	8075511	3000288	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Aldo_ket_red	e1ynpB1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Aldo_ket_red	ECOD (1.6)
A	Aldo_ket_red	e1ynpA1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Aldo_ket_red	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.20.20.100	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	NADP-dependent oxidoreductase domain	CATH (4.3.0)
A	3.20.20.100	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	NADP-dependent oxidoreductase domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00248	Aldo/keto reductase family (Aldo_ket_red)	Aldo/keto reductase family	This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity [2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	oxidoreductase	oxidoreductase activity catalytic activity binding nucleoside phosphate binding organic cyclic compound binding nucleotide binding heterocyclic compound binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR036812	NADP-dependent oxidoreductase domain superfamily	Homologous Superfamily
A, B	IPR053135	Aldo-Keto Reductase 2 Subfamily Oxidoreductase	Family
A, B	IPR023210	NADP-dependent oxidoreductase domain	Domain
A, B	IPR020471	Aldo-keto reductase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.