1ZTX
West Nile Virus Envelope Protein DIII in complex with neutralizing E16 antibody Fab
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth E] | d1ztxe_ | All beta proteins | Immunoglobulin-like beta-sandwich | E set domains | Class II viral fusion proteins C-terminal domain | automated matches | (West Nile virus ) [TaxId: 11082 ], | SCOPe (2.08) |
B [auth H] | d1ztxh1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | C1 set domains (antibody constant domain-like) | Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma | (Mus musculus ) [TaxId: 10090 ], | SCOPe (2.08) |
B [auth H] | d1ztxh2 | Artifacts | Tags | Tags | Tags | N-terminal Tags | (Mus musculus ) [TaxId: 10090 ], | SCOPe (2.08) |
C [auth L] | d1ztxl2 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | C1 set domains (antibody constant domain-like) | automated matches | (Mus musculus ) [TaxId: 10090 ], | SCOPe (2.08) |
C [auth L] | d1ztxl1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | (Mus musculus ) [TaxId: 10090 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A [auth E] | SCOP2 Family | Class II viral fusion proteins C-terminal domain | 8054986 | 4007569 | SCOP2 (2022-06-29) |
A [auth E] | SCOP2 Superfamily | E set domains | 8054987 | 3000070 | SCOP2 (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth E] | Flavi_glycop_C | e1ztxE1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: Flavi_glycop_C | ECOD (1.6) |
B [auth H] | V-set_8 | e1ztxH2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_8 | ECOD (1.6) |
B [auth H] | C1-set_1 | e1ztxH1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_1 | ECOD (1.6) |
C [auth L] | C1-set_4 | e1ztxL2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_4 | ECOD (1.6) |
C [auth L] | V-set | e1ztxL1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A [auth E] | 2.60.40.350 | Mainly Beta | Sandwich | Immunoglobulin-like | CATH (4.3.0) | |
B [auth H] | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
C [auth L] | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
IMGT Antibody Annotation IMGT Database Homepage
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|---|---|---|---|---|---|---|---|
B [auth H] | E16 | VH-CH1 | Mus musculus (house mouse) | IGHV1-9*01, IGHJ2*01, IGHG2B*02 | V-DOMAIN VH, C-DOMAIN CH1 | IG | FAB-GAMMA-2B_KAPPA | IMGT (202443-0) |
C [auth L] | E16 | L-KAPPA | Mus musculus (house mouse) | IGKV6-25*01, IGKJ5*01, IGKC*01, IGKC*02 | V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA | IG | FAB-GAMMA-2B_KAPPA | IMGT (202443-0) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
B [auth H] | Heavy Chain | IGHV1 | - | envelope protein | SAbDab (2024-11-01) |
C [auth L] | Light Chain | IGKV6 | Kappa | envelope protein | SAbDab (2024-11-01) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth E] | PF02832 | Flavivirus glycoprotein, immunoglobulin-like domain (Flavi_glycop_C) | Flavivirus glycoprotein, immunoglobulin-like domain | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A [auth E] | IPR011998 | Envelope glycoprotein E, central and dimerisation domain, flavivirus | Domain |
A [auth E] | IPR013755 | Flaviviral glycoprotein E, central domain, subdomain 1 | Homologous Superfamily |
A [auth E] | IPR038055 | Flaviviral glycoprotein E, dimerisation domain | Homologous Superfamily |
A [auth E] | IPR014756 | Immunoglobulin E-set | Homologous Superfamily |
A [auth E] | IPR027287 | Glycoprotein E, immunoglobulin-like domain, flavivirus | Domain |
A [auth E] | IPR013756 | Flaviviral glycoprotein E, central domain, subdomain 2 | Homologous Superfamily |
A [auth E] | IPR000336 | Flavivirus/Alphavirus glycoprotein, immunoglobulin-like domain superfamily | Homologous Superfamily |
A [auth E] | IPR036253 | Flavivirus glycoprotein, central and dimerisation domain superfamily | Homologous Superfamily |