2A1L

Rat PITP-Beta Complexed to Phosphatidylcholine

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2a1la1	Alpha and beta proteins (a+b)	TBP-like	Bet v1-like	Phoshatidylinositol transfer protein, PITP	Phoshatidylinositol transfer protein, PITP	Norway rat (Rattus norvegicus ) [TaxId: 10116 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Phoshatidylinositol transfer protein, PITP	8024068	4003635	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Bet v1-like	8036447	3000738	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	IP_trans	e2a1lA1	A: a+b two layers	X: TBP-like	H: Bet v1-like (From Topology)	T: Bet v1-like	F: IP_trans	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.530.20	Alpha Beta	2-Layer Sandwich	Alpha-D-Glucose-1,6-Bisphosphate	Chain A, domain 4	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF02121	Phosphatidylinositol transfer protein (IP_trans)	Phosphatidylinositol transfer protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Phosphatidylinositol transfer protein beta isoform	phosphatidylcholine transporter activity lipid transporter activity transporter activity phospholipid transporter activity binding phospholipid binding lipid binding phosphatidylinositol binding phospholipid transfer activity phosphatidylcholine transfer activity lipid transfer activity cation binding ion binding phosphatidylcholine binding phosphatidylcholine transporter activity lipid transporter activity transporter activity phospholipid transporter activity binding phospholipid binding lipid binding phosphatidylinositol binding phospholipid transfer activity phosphatidylcholine transfer activity lipid transfer activity cation binding ion binding phosphatidylcholine binding quaternary ammonium group binding small molecule binding phosphatidylinositol transfer activity sphingomyelin transfer activity sphingolipid transfer activity sphingolipid transporter activity	localization transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum cellular process establishment of localization Golgi vesicle transport vesicle-mediated transport macromolecule localization phospholipid transport lipid localization lipid transport organophosphate ester transport developmental process multicellular organism development localization transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum cellular process establishment of localization Golgi vesicle transport vesicle-mediated transport macromolecule localization phospholipid transport lipid localization lipid transport organophosphate ester transport developmental process multicellular organism development multicellular organismal process embryo development ending in birth or egg hatching chordate embryonic development anatomical structure development embryo development in utero embryonic development	membrane-bounded organelle intracellular organelle intracellular anatomical structure Golgi apparatus organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle endomembrane system Golgi membrane membrane bounding membrane of organelle organelle membrane organelle subcompartment membrane-bounded organelle intracellular organelle intracellular anatomical structure Golgi apparatus organelle cytoplasm cellular anatomical entity intracellular membrane-bounded organelle endomembrane system Golgi membrane membrane bounding membrane of organelle organelle membrane organelle subcompartment endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum endoplasmic reticulum membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR001666	Phosphatidylinositol transfer protein	Family
A	IPR023393	START-like domain superfamily	Homologous Superfamily

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A	OPM	Monotopic/peripheral	Alpha + Beta monotopic/peripheral	Bet v1-like	Phosphatidylinositol transfer protein (PITP)

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.