Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2ahra1 All alpha proteins 6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like ProC C-terminal domain-like Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Ad2ahra2 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase-like, N-terminal domain Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Ad2ahra3 Artifacts Tags Tags Tags N-terminal Tags (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Bd2ahrb1 All alpha proteins 6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like ProC C-terminal domain-like Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Bd2ahrb2 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase-like, N-terminal domain Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Bd2ahrb3 Artifacts Tags Tags Tags N-terminal Tags (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Cd2ahrc1 All alpha proteins 6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like ProC C-terminal domain-like Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Cd2ahrc2 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase-like, N-terminal domain Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Dd2ahrd1 All alpha proteins 6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like ProC C-terminal domain-like Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Dd2ahrd2 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase-like, N-terminal domain Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Dd2ahrd3 Artifacts Tags Tags Tags N-terminal Tags (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Ed2ahre1 All alpha proteins 6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like ProC C-terminal domain-like Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Ed2ahre2 Alpha and beta proteins (a/b) NAD(P)-binding Rossmann-fold domains NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase-like, N-terminal domain Pyrroline-5-carboxylate reductase ProC (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)
Ed2ahre3 Artifacts Tags Tags Tags N-terminal Tags (Streptococcus pyogenes M1 GAS ) [TaxId: 160490 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B Superfamily6-phosphogluconate dehydrogenase-like 8058540 3000048 SCOP2B (2022-06-29)
BSCOP2B Superfamily6-phosphogluconate dehydrogenase-like 8058540 3000048 SCOP2B (2022-06-29)
CSCOP2B Superfamily6-phosphogluconate dehydrogenase-like 8058540 3000048 SCOP2B (2022-06-29)
DSCOP2B Superfamily6-phosphogluconate dehydrogenase-like 8058540 3000048 SCOP2B (2022-06-29)
ESCOP2B Superfamily6-phosphogluconate dehydrogenase-like 8058540 3000048 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AP5CR_dimere2ahrA1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: P5CR_dimerECOD (1.6)
AF420_oxidorede2ahrA2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: F420_oxidoredECOD (1.6)
BP5CR_dimere2ahrB1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: P5CR_dimerECOD (1.6)
BF420_oxidorede2ahrB2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: F420_oxidoredECOD (1.6)
CP5CR_dimere2ahrC1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: P5CR_dimerECOD (1.6)
CF420_oxidorede2ahrC2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: F420_oxidoredECOD (1.6)
DP5CR_dimere2ahrD1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: P5CR_dimerECOD (1.6)
DF420_oxidorede2ahrD2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: F420_oxidoredECOD (1.6)
EP5CR_dimere2ahrE1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: P5CR_dimerECOD (1.6)
EF420_oxidorede2ahrE2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: F420_oxidoredECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF14748Pyrroline-5-carboxylate reductase dimerisation (P5CR_dimer)Pyrroline-5-carboxylate reductase dimerisationPyrroline-5-carboxylate reductase consists of two domains, an N-terminal catalytic domain (Pfam:PF03807) and a C-terminal dimerisation domain. This is the dimerisation domain [1].Domain
A, B, C, D, E
PF03807NADP oxidoreductase coenzyme F420-dependent (F420_oxidored)NADP oxidoreductase coenzyme F420-dependent- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
putative pyrroline carboxylate reductase