2BXX

Crystal structure of the N-terminal domain of IBV coronavirus nucleocapsid. Native crystal form

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2bxxa1	All beta proteins	Coronavirus RNA-binding domain	Coronavirus RNA-binding domain	Coronavirus RNA-binding domain	Nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)
B	d2bxxb_	All beta proteins	Coronavirus RNA-binding domain	Coronavirus RNA-binding domain	Coronavirus RNA-binding domain	Nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	SARS coronavirus nucleoprotein RNA-binding domain-like	8080133	3000498	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	SARS coronavirus nucleoprotein RNA-binding domain-like	8080133	3000498	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Corona_nucleoca_1st	e2bxxA1	A: beta complex topology	X: Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) (From Topology)	H: Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) (From Topology)	T: Coronavirus RNA-binding domain (N-terminal part of Pfam 00937)	F: Corona_nucleoca_1st	ECOD (1.6)
B	Corona_nucleoca_1st	e2bxxB1	A: beta complex topology	X: Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) (From Topology)	H: Coronavirus RNA-binding domain (N-terminal part of Pfam 00937) (From Topology)	T: Coronavirus RNA-binding domain (N-terminal part of Pfam 00937)	F: Corona_nucleoca_1st	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00937	Coronavirus nucleocapsid (CoV_nucleocap)	Coronavirus nucleocapsid	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	NUCLEOCAPSID PROTEIN	RNA binding binding organic cyclic compound binding nucleic acid binding identical protein binding protein binding	-	host intracellular membrane-bounded organelle host cellular component host intracellular part host cell endoplasmic reticulum-Golgi intermediate compartment host cell cytoplasm host cell part host intracellular region cellular anatomical entity host cell cytoplasm part host intracellular organelle protein-containing complex ribonucleoprotein complex viral nucleocapsid viral capsid host intracellular membrane-bounded organelle host cellular component host intracellular part host cell endoplasmic reticulum-Golgi intermediate compartment host cell cytoplasm host cell part host intracellular region cellular anatomical entity host cell cytoplasm part host intracellular organelle protein-containing complex ribonucleoprotein complex viral nucleocapsid viral capsid virion component host cell Golgi apparatus

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR001218	Nucleocapsid protein, coronavirus	Family
A, B	IPR044344	Nucleocapsid (N) protein, C-terminal domain, coronavirus	Domain
A, B	IPR042547	Nucleocapsid protein, gammacoronavirus	Family
A, B	IPR037195	Nucleocapsid protein, N-terminal	Homologous Superfamily
A, B	IPR037179	Nucleocapsid protein, C-terminal	Homologous Superfamily
A, B	IPR044345	Nucleocapsid (N) protein, N-terminal domain, coronavirus	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.