2C4K
Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39)
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2 Family | Phosphoribosylpyrophosphate synthetase-like | 8026946 | 4000640 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | PRTase-like | 8039326 | 3000060 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | PRTase-like | 8039325 | 3000060 | SCOP2 (2022-06-29) |
B | SCOP2B Superfamily | PRTase-like | 8039325 | 3000060 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | PRTase-like | 8039325 | 3000060 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | PRTase-like | 8039325 | 3000060 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | PRTase-like | 8039325 | 3000060 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | PRTase-like | 8039325 | 3000060 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Pribosyltran_N | e2c4kA1 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyltran_N | ECOD (1.6) |
A | Pribosyl_synth | e2c4kA2 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyl_synth | ECOD (1.6) |
B | Pribosyltran_N | e2c4kB1 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyltran_N | ECOD (1.6) |
B | Pribosyl_synth | e2c4kB2 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyl_synth | ECOD (1.6) |
C | Pribosyltran_N | e2c4kC1 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyltran_N | ECOD (1.6) |
C | Pribosyl_synth | e2c4kC2 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyl_synth | ECOD (1.6) |
D | Pribosyltran_N | e2c4kD1 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyltran_N | ECOD (1.6) |
D | Pribosyl_synth | e2c4kD2 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyl_synth | ECOD (1.6) |
E | Pribosyltran_N | e2c4kE1 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyltran_N | ECOD (1.6) |
E | Pribosyl_synth | e2c4kE2 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyl_synth | ECOD (1.6) |
F | Pribosyltran_N | e2c4kF1 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyltran_N | ECOD (1.6) |
F | Pribosyl_synth | e2c4kF2 | A: a/b three-layered sandwiches | X: PRTase-like (From Topology) | H: PRTase-like (From Topology) | T: PRTase-like | F: Pribosyl_synth | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.2020 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
B | 3.40.50.2020 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
C | 3.40.50.2020 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
D | 3.40.50.2020 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
E | 3.40.50.2020 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
F | 3.40.50.2020 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF14572 | Phosphoribosyl synthetase-associated domain (Pribosyl_synth) | Phosphoribosyl synthetase-associated domain | This family includes several examples of enzymes from class EC:2.7.6.1, phosphoribosyl-pyrophosphate transferase. | Domain | |
PF13793 | N-terminal domain of ribose phosphate pyrophosphokinase (Pribosyltran_N) | N-terminal domain of ribose phosphate pyrophosphokinase | This family is frequently found N-terminal to the Pribosyltran, Pfam:PF00156. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
Q14558 | :