2E4A
Crystal Structure of Human D-Amino Acid Oxidase in complex with o-aminobenzoate
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Flavoreductase-like | 8068931 | 3000055 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Flavoreductase-like | 8068931 | 3000055 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Flavoreductase-like | 8068931 | 3000055 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Flavoreductase-like | 8068931 | 3000055 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | DAO_2nd | e2e4aA1 | A: a+b two layers | X: FAD-linked reductases, C-terminal domain-like | H: FAD-linked reductases-C (From Topology) | T: FAD-linked reductases-C | F: DAO_2nd | ECOD (1.6) |
A | DAO_1st | e2e4aA2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: Nucleotide-binding domain | F: DAO_1st | ECOD (1.6) |
B | DAO_2nd | e2e4aB1 | A: a+b two layers | X: FAD-linked reductases, C-terminal domain-like | H: FAD-linked reductases-C (From Topology) | T: FAD-linked reductases-C | F: DAO_2nd | ECOD (1.6) |
B | DAO_1st | e2e4aB2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: Nucleotide-binding domain | F: DAO_1st | ECOD (1.6) |
C | DAO_2nd | e2e4aC1 | A: a+b two layers | X: FAD-linked reductases, C-terminal domain-like | H: FAD-linked reductases-C (From Topology) | T: FAD-linked reductases-C | F: DAO_2nd | ECOD (1.6) |
C | DAO_1st | e2e4aC2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: Nucleotide-binding domain | F: DAO_1st | ECOD (1.6) |
D | DAO_2nd | e2e4aD1 | A: a+b two layers | X: FAD-linked reductases, C-terminal domain-like | H: FAD-linked reductases-C (From Topology) | T: FAD-linked reductases-C | F: DAO_2nd | ECOD (1.6) |
D | DAO_1st | e2e4aD2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: Nucleotide-binding domain | F: DAO_1st | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.720 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain | CATH (4.3.0) |
A | 3.30.9.10 | Alpha Beta | 2-Layer Sandwich | D-Amino Acid Oxidase | Chain A, domain 2 | CATH (4.3.0) |
B | 3.40.50.720 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain | CATH (4.3.0) |
B | 3.30.9.10 | Alpha Beta | 2-Layer Sandwich | D-Amino Acid Oxidase | Chain A, domain 2 | CATH (4.3.0) |
C | 3.40.50.720 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain | CATH (4.3.0) |
C | 3.30.9.10 | Alpha Beta | 2-Layer Sandwich | D-Amino Acid Oxidase | Chain A, domain 2 | CATH (4.3.0) |
D | 3.40.50.720 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain | CATH (4.3.0) |
D | 3.30.9.10 | Alpha Beta | 2-Layer Sandwich | D-Amino Acid Oxidase | Chain A, domain 2 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01266 | FAD dependent oxidoreductase (DAO) | FAD dependent oxidoreductase | This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target   | Associated Disease |
---|---|---|
P14920 | :