Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Bd2fbwb2 All alpha proteins Globin-like alpha-helical ferredoxin Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain Succinate dehydogenase (Gallus gallus ) [TaxId: 9031 ], SCOPe (2.08)
Bd2fbwb1 Alpha and beta proteins (a+b) beta-Grasp (ubiquitin-like) 2Fe-2S ferredoxin-like 2Fe-2S ferredoxin domains from multidomain proteins Succinate dehydogenase iron-sulfur protein, N-terminal domain (Gallus gallus ) [TaxId: 9031 ], SCOPe (2.08)
F [auth O]d2fbwo2 All alpha proteins Globin-like alpha-helical ferredoxin Fumarate reductase/Succinate dehydogenase iron-sulfur protein, C-terminal domain Succinate dehydogenase (Gallus gallus ) [TaxId: 9031 ], SCOPe (2.08)
F [auth O]d2fbwo1 Alpha and beta proteins (a+b) beta-Grasp (ubiquitin-like) 2Fe-2S ferredoxin-like 2Fe-2S ferredoxin domains from multidomain proteins Succinate dehydogenase iron-sulfur protein, N-terminal domain (Gallus gallus ) [TaxId: 9031 ], SCOPe (2.08)
Cd2fbwc_ Membrane and cell surface proteins and peptides Heme-binding four-helical bundle Fumarate reductase respiratory complex transmembrane subunits Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) automated matches (Gallus gallus ) [TaxId: 9031 ], SCOPe (2.08)
G [auth P]d2fbwp_ Membrane and cell surface proteins and peptides Heme-binding four-helical bundle Fumarate reductase respiratory complex transmembrane subunits Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) automated matches (Gallus gallus ) [TaxId: 9031 ], SCOPe (2.08)
Dd2fbwd_ Membrane and cell surface proteins and peptides Heme-binding four-helical bundle Fumarate reductase respiratory complex transmembrane subunits Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) automated matches (Gallus gallus ) [TaxId: 9031 ], SCOPe (2.08)
H [auth Q]d2fbwq_ Membrane and cell surface proteins and peptides Heme-binding four-helical bundle Fumarate reductase respiratory complex transmembrane subunits Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) automated matches (Gallus gallus ) [TaxId: 9031 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ASucc_DH_flav_Ce2fbwA2 A: alpha bundlesX: Spectrin repeat-likeH: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain (From Topology)T: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domainF: Succ_DH_flav_CECOD (1.6)
AFAD_binding_2e2fbwA3 A: a+b complex topologyX: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)H: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)T: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domainF: FAD_binding_2ECOD (1.6)
AFAD_binding_3_1ste2fbwA1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: FAD_binding_3_1stECOD (1.6)
E [auth N]Succ_DH_flav_Ce2fbwN3 A: alpha bundlesX: Spectrin repeat-likeH: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain (From Topology)T: Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domainF: Succ_DH_flav_CECOD (1.6)
E [auth N]FAD_binding_2e2fbwN2 A: a+b complex topologyX: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)H: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain (From Topology)T: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domainF: FAD_binding_2ECOD (1.6)
E [auth N]FAD_binding_3_1ste2fbwN1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: FAD_binding_3_1stECOD (1.6)
BFer4_8e2fbwB1 A: alpha arraysX: alpha-helical ferredoxin-likeH: alpha-helical ferredoxin (From Topology)T: alpha-helical ferredoxinF: Fer4_8ECOD (1.6)
BFer2_3e2fbwB2 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: Fer2_3ECOD (1.6)
F [auth O]Fer4_8e2fbwO1 A: alpha arraysX: alpha-helical ferredoxin-likeH: alpha-helical ferredoxin (From Topology)T: alpha-helical ferredoxinF: Fer4_8ECOD (1.6)
F [auth O]Fer2_3e2fbwO2 A: a+b two layersX: beta-GraspH: Ubiquitin-relatedT: Ubiquitin-likeF: Fer2_3ECOD (1.6)
CSdh_cyte2fbwC1 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Fumarate reductase respiratory complex transmembrane subunitsF: Sdh_cytECOD (1.6)
G [auth P]Sdh_cyte2fbwP1 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Fumarate reductase respiratory complex transmembrane subunitsF: Sdh_cytECOD (1.6)
DCybSe2fbwD1 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Fumarate reductase respiratory complex transmembrane subunitsF: CybSECOD (1.6)
H [auth Q]CybSe2fbwQ1 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Fumarate reductase respiratory complex transmembrane subunitsF: CybSECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.50.50.60 Alpha Beta 3-Layer(bba) Sandwich FAD/NAD(P)-binding domain FAD/NAD(P)-binding domainCATH (4.3.0)
A3.90.700.10 Alpha Beta Alpha-Beta Complex Flavocytochrome C3 Chain A, domain 1CATH (4.3.0)
A1.20.58.100 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)
A4.10.80.40 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 succinate dehydrogenase protein domainCATH (4.3.0)
E [auth N]3.50.50.60 Alpha Beta 3-Layer(bba) Sandwich FAD/NAD(P)-binding domain FAD/NAD(P)-binding domainCATH (4.3.0)
E [auth N]3.90.700.10 Alpha Beta Alpha-Beta Complex Flavocytochrome C3 Chain A, domain 1CATH (4.3.0)
E [auth N]1.20.58.100 Mainly Alpha Up-down Bundle Methane Monooxygenase Hydroxylase Chain G, domain 1CATH (4.3.0)
E [auth N]4.10.80.40 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 succinate dehydrogenase protein domainCATH (4.3.0)
B3.10.20.30 Alpha Beta Roll Ubiquitin-like (UB roll) Beta-grasp domainCATH (4.3.0)
B1.10.1060.10 Mainly Alpha Orthogonal Bundle Fumarate Reductase Iron-sulfur Protein Chain B, domain 2CATH (4.3.0)
F [auth O]3.10.20.30 Alpha Beta Roll Ubiquitin-like (UB roll) Beta-grasp domainCATH (4.3.0)
F [auth O]1.10.1060.10 Mainly Alpha Orthogonal Bundle Fumarate Reductase Iron-sulfur Protein Chain B, domain 2CATH (4.3.0)
C1.20.5.540 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)
C1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunitCATH (4.3.0)
G [auth P]1.20.5.540 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)
G [auth P]1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunitCATH (4.3.0)
D1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunitCATH (4.3.0)
H [auth Q]1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunitCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A,
E [auth N]
PF02910Fumarate reductase flavoprotein C-term (Succ_DH_flav_C)Fumarate reductase flavoprotein C-termThis family contains fumarate reductases, succinate dehydrogenases and L-aspartate oxidases.Domain
A,
E [auth N]
PF00890FAD binding domain (FAD_binding_2)FAD binding domain- Family
B,
F [auth O]
PF130852Fe-2S iron-sulfur cluster binding domain (Fer2_3)2Fe-2S iron-sulfur cluster binding domainThe 2Fe-2S ferredoxin family have a general core structure consisting of beta(2)-alpha-beta(2) which abeta-grasp type fold. The domain is around one hundred amino acids with four conserved cysteine residues to which the 2Fe-2S cluster is ligated.Domain
B,
F [auth O]
PF135344Fe-4S dicluster domain (Fer4_17)4Fe-4S dicluster domainThis family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.Domain
C,
G [auth P]
PF01127Succinate dehydrogenase/Fumarate reductase transmembrane subunit (Sdh_cyt)Succinate dehydrogenase/Fumarate reductase transmembrane subunit- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A,
E [auth N]
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
B,
F [auth O]
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
C,
G [auth P]
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
D,
H [auth Q]
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A,
E [auth N]
IPR015939Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminalDomain
A,
E [auth N]
IPR003952Fumarate reductase/succinate dehydrogenase, FAD-binding siteBinding Site
A,
E [auth N]
IPR037099Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamilyHomologous Superfamily
A,
E [auth N]
IPR036188FAD/NAD(P)-binding domain superfamilyHomologous Superfamily
A,
E [auth N]
IPR003953FAD-dependent oxidoreductase 2, FAD binding domainDomain
A,
E [auth N]
IPR030664FAD-dependent oxidoreductase SdhA/FrdA/AprAFamily
A,
E [auth N]
IPR027477Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamilyHomologous Superfamily
A,
E [auth N]
IPR014006Succinate dehydrogenase/fumarate reductase, flavoprotein subunitFamily
A,
E [auth N]
IPR011281Succinate dehydrogenase, flavoprotein subunitFamily
B,
F [auth O]
IPR025192Succinate dehydogenase/fumarate reductase N-terminalDomain
B,
F [auth O]
IPR0360102Fe-2S ferredoxin-like superfamilyHomologous Superfamily
B,
F [auth O]
IPR0010412Fe-2S ferredoxin-type iron-sulfur binding domainDomain
B,
F [auth O]
IPR0060582Fe-2S ferredoxin, iron-sulphur binding siteBinding Site
B,
F [auth O]
IPR004489Succinate dehydrogenase/fumarate reductase iron-sulphur proteinFamily
B,
F [auth O]
IPR009051Alpha-helical ferredoxinHomologous Superfamily
B,
F [auth O]
IPR050573Succinate Dehydrogenase/Fumarate Reductase Iron-SulfurFamily
B,
F [auth O]
IPR0179004Fe-4S ferredoxin, iron-sulphur binding, conserved siteConserved Site
B,
F [auth O]
IPR0178964Fe-4S ferredoxin-type, iron-sulphur binding domainDomain
B,
F [auth O]
IPR012675Beta-grasp domain superfamilyHomologous Superfamily
C,
G [auth P]
IPR018495Succinate dehydrogenase, cytochrome b subunit, conserved siteConserved Site
C,
G [auth P]
IPR034804Fumarate reductase/succinate dehydrogenase, transmembrane subunitHomologous Superfamily
C,
G [auth P]
IPR000701Succinate dehydrogenase/fumarate reductase type B, transmembrane subunitFamily
C,
G [auth P]
IPR014314Succinate dehydrogenase, cytochrome b556 subunitFamily
D,
H [auth Q]
IPR034804Fumarate reductase/succinate dehydrogenase, transmembrane subunitHomologous Superfamily
D,
H [auth Q]
IPR007992Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybSFamily