Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
BSCOP2B SuperfamilyEF-Tu post-G domain-like 8056352 3002024 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyEF-Tu post-G domain-like 8056350 3002024 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
BGTP_EFTU_D2_1e2hcjB4 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Alanine racemase-CF: GTP_EFTU_D2_1ECOD (1.6)
BGTP_EFTU_D3e2hcjB2 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: Aminomethyltransferase beta-barrel domainF: GTP_EFTU_D3ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B3.40.50.300 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold P-loop containing nucleotide triphosphate hydrolasesCATH (4.3.0)
B2.40.30.10 Mainly Beta Beta Barrel Elongation Factor Tu (Ef-tu) domain 3CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00009Elongation factor Tu GTP binding domain (GTP_EFTU)Elongation factor Tu GTP binding domainThis domain contains a P-loop motif, also found in several other families such as Pfam:PF00071, Pfam:PF00025 and Pfam:PF00063. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains.Domain
PF03143Elongation factor Tu C-terminal domain (GTP_EFTU_D3)Elongation factor Tu C-terminal domainElongation factor Tu consists of three structural domains, this is the third domain. This domain adopts a beta barrel structure. This the third domain is involved in binding to both charged tRNA [1] and binding to EF-Ts Pfam:PF00889 [2].Domain
PF03144Elongation factor Tu domain 2 (GTP_EFTU_D2)Elongation factor Tu domain 2Elongation factor Tu consists of three structural domains, this is the second domain. This domain adopts a beta barrel structure. This the second domain is involved in binding to charged tRNA [1]. This domain is also found in other proteins such as e ...Elongation factor Tu consists of three structural domains, this is the second domain. This domain adopts a beta barrel structure. This the second domain is involved in binding to charged tRNA [1]. This domain is also found in other proteins such as elongation factor G and translation initiation factor IF-2. This domain is structurally related to Pfam:PF03143, and in fact has weak sequence matches to this domain.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Protein chain elongation factor EF-Tu
Protein chain elongation factor EF-Tu

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR005225Small GTP-binding domainDomain
IPR000795Translational (tr)-type GTP-binding domainDomain
IPR033720Elongation factor Tu, domain 2Domain
IPR009001Translation elongation factor EF1A/initiation factor IF2gamma, C-terminalHomologous Superfamily
IPR031157Tr-type G domain, conserved siteConserved Site
IPR004541Translation elongation factor EFTu/EF1A, bacterial/organelleFamily
IPR004161Translation elongation factor EFTu-like, domain 2Domain
IPR009000Translation protein, beta-barrel domain superfamilyHomologous Superfamily
IPR004160Translation elongation factor EFTu/EF1A, C-terminalDomain
IPR050055Elongation factor Tu GTPaseFamily
IPR041709Elongation factor Tu (EF-Tu), GTP-binding domainDomain
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
IPR005225Small GTP-binding domainDomain
IPR000795Translational (tr)-type GTP-binding domainDomain
IPR033720Elongation factor Tu, domain 2Domain
IPR009001Translation elongation factor EF1A/initiation factor IF2gamma, C-terminalHomologous Superfamily
IPR031157Tr-type G domain, conserved siteConserved Site
IPR004541Translation elongation factor EFTu/EF1A, bacterial/organelleFamily
IPR004161Translation elongation factor EFTu-like, domain 2Domain
IPR009000Translation protein, beta-barrel domain superfamilyHomologous Superfamily
IPR004160Translation elongation factor EFTu/EF1A, C-terminalDomain
IPR050055Elongation factor Tu GTPaseFamily
IPR041709Elongation factor Tu (EF-Tu), GTP-binding domainDomain
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
CSO Parent Component: CYS

RESIDAA0205

PSI-MOD :  L-cysteine sulfenic acid MOD:00210