2HX5

Crystal structure of a putative thioesterase (pmt_2055) from prochlorococcus marinus str. mit 9313 at 1.50 A resolution

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2hx5a1	Alpha and beta proteins (a+b)	Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	4HBT-like	Hypothetical protein PMT2055	(Prochlorococcus marinus str. MIT 9313 ) [TaxId: 74547 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	4HBT-like	8030088	4001116	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Thioesterase/thiol ester dehydrase-isomerase-like	8042467	3000149	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	4HBT_2	e2hx5A1	A: a+b two layers	X: Thioesterase/thiol ester dehydrase-isomerase-like	H: Thioesterase/thiol ester dehydrase-isomerase (From Topology)	T: Thioesterase/thiol ester dehydrase-isomerase	F: 4HBT_2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.129.10	Alpha Beta	Roll	Thiol Ester Dehydrase	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF13279	Thioesterase-like superfamily (4HBT_2)	Thioesterase-like superfamily	This family contains a wide variety of enzymes, principally thioesterases. These enzymes are part of the Hotdog fold superfamily [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Hypothetical protein	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity hydrolase activity, acting on ester bonds thiolester hydrolase activity hydrolase activity catalytic activity acyl-CoA hydrolase activity	vitamin K metabolic process small molecule biosynthetic process fat-soluble vitamin metabolic process cellular biosynthetic process cellular metabolic process vitamin biosynthetic process vitamin metabolic process phylloquinone metabolic process cellular ketone metabolic process biosynthetic process phylloquinone biosynthetic process vitamin K biosynthetic process fat-soluble vitamin biosynthetic process small molecule metabolic process vitamin K metabolic process small molecule biosynthetic process fat-soluble vitamin metabolic process cellular biosynthetic process cellular metabolic process vitamin biosynthetic process vitamin metabolic process phylloquinone metabolic process cellular ketone metabolic process biosynthetic process phylloquinone biosynthetic process vitamin K biosynthetic process fat-soluble vitamin biosynthetic process small molecule metabolic process metabolic process cellular process ketone biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR050563	4-hydroxybenzoyl-CoA thioesterase	Family
A	IPR022829	1,4-dihydroxy-2-naphthoyl-CoA hydrolase	Family
A	IPR029069	HotDog domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.