2NS1
Crystal structure of the e. coli ammonia channel AMTB complexed with the signal transduction protein GLNK
External Resource: Annotation
- Domain Annotation: SCOP/SCOPe Classification
- Domain Annotation: SCOP2 Classification
- Domain Annotation: ECOD Classification
- Domain Annotation: CATH
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
- Membrane Protein Annotation: OPM
- Membrane Protein Annotation: PDBTM
- Membrane Protein Annotation: mpstruc
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d2ns1a_ | Membrane and cell surface proteins and peptides | Ammonium transporter | Ammonium transporter | automated matches | automated matches | (Escherichia coli K-12 ) [TaxId: 83333 ], | SCOPe (2.08) |
B | d2ns1b1 | Alpha and beta proteins (a+b) | Ferredoxin-like | GlnB-like | Prokaryotic signal transducing protein | PII-homolog GlnK | (Escherichia coli K-12 ) [TaxId: 83333 ], | SCOPe (2.08) |
B | d2ns1b2 | Artifacts | Tags | Tags | Tags | N-terminal Tags | (Escherichia coli K-12 ) [TaxId: 83333 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Ammonium_transp_1 | e2ns1A1 | A: alpha complex topology | X: Ammonium transporter-related (From Homology) | H: Ammonium transporter-related | T: Ammonium transporter | F: Ammonium_transp_1 | ECOD (1.6) |
B | P-II | e2ns1B1 | A: a+b two layers | X: Alpha-beta plaits | H: GlnB-like (From Topology) | T: GlnB-like | F: P-II | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 1.10.3430.10 | Mainly Alpha | Orthogonal Bundle | Ammonium transporter fold | Ammonium transporter AmtB like domains | CATH (4.3.0) |
B | 3.30.70.120 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00909 | Ammonium Transporter Family (Ammonium_transp) | Ammonium Transporter Family | - | Family | |
PF00543 | Nitrogen regulatory protein P-II (P-II) | Nitrogen regulatory protein P-II | P-II modulates the activity of glutamine synthetase. It is a tetrameric protein encoded by the glnB gene, a component of the adenylation cascade involved in the regulation of GS activity [1,2]. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR018047 | Ammonium transporter, conserved site | Conserved Site | |
IPR029020 | Ammonium/urea transporter | Homologous Superfamily | |
IPR001905 | Ammonium transporter | Family | |
IPR024041 | Ammonium transporter AmtB-like domain | Domain | |
IPR015867 | Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal | Homologous Superfamily | |
IPR011322 | Nitrogen regulatory PII-like, alpha/beta | Homologous Superfamily | |
IPR002187 | Nitrogen regulatory protein PII | Family | |
IPR002332 | Nitrogen regulatory protein P-II, urydylation site | PTM | |
IPR017918 | Nitrogen regulatory protein PII, conserved site | Conserved Site |
Membrane Protein Annotation: OPM OPM Database Homepage
Chains | External Link | Type | Class | Superfamily | Family |
---|---|---|---|---|---|
OPM | Transmembrane | Alpha-helical polytopic | Ammonia/urea transporters/Na+ exporter | Ammonia transporter Amt |
Membrane Protein Annotation: PDBTM PDBTM Database Homepage
Chains | External Link | Comment |
---|---|---|
PDBTM | Annotated as membrane protein by PDBTM |
Membrane Protein Annotation: mpstruc mpstruc Database Homepage
Chains | Resource Link | Group | Subgroup | Protein |
---|---|---|---|---|
mpstruc | TRANSMEMBRANE PROTEINS: ALPHA-HELICAL | Channels: Amt/Mep/Rh proteins | AmtB ammonia channel in complex with inhibitory GlnK |