2NTI
Crystal structure of PCNA123 heterotrimer.
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
D [auth A] | PCNA_C | e2ntiA2 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_C | ECOD (1.6) |
D [auth A] | PCNA_N_1 | e2ntiA1 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_N_1 | ECOD (1.6) |
A [auth D] | PCNA_C | e2ntiD2 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_C | ECOD (1.6) |
A [auth D] | PCNA_N_1 | e2ntiD1 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_N_1 | ECOD (1.6) |
G | PCNA_C | e2ntiG2 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_C | ECOD (1.6) |
G | PCNA_N_1 | e2ntiG1 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_N_1 | ECOD (1.6) |
H | PCNA_C | e2ntiH2 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_C | ECOD (1.6) |
H | PCNA_N_1 | e2ntiH1 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_N_1 | ECOD (1.6) |
B [auth E] | PCNA_C | e2ntiE2 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_C | ECOD (1.6) |
B [auth E] | PCNA_N_1 | e2ntiE1 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_N_1 | ECOD (1.6) |
E [auth B] | PCNA_C | e2ntiB2 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_C | ECOD (1.6) |
E [auth B] | PCNA_N_1 | e2ntiB1 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_N_1 | ECOD (1.6) |
F [auth C] | PCNA_C | e2ntiC2 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_C | ECOD (1.6) |
F [auth C] | PCNA_N_1 | e2ntiC1 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_N_1 | ECOD (1.6) |
C [auth F] | PCNA_C | e2ntiF2 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_C | ECOD (1.6) |
C [auth F] | PCNA_N_1 | e2ntiF1 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_N_1 | ECOD (1.6) |
I | PCNA_C | e2ntiI2 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_C | ECOD (1.6) |
I | PCNA_N_1 | e2ntiI1 | A: a+b two layers | X: DNA clamp (From Topology) | H: DNA clamp (From Topology) | T: DNA clamp | F: PCNA_N_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
D [auth A] | 3.70.10.10 | Alpha Beta | Box | Proliferating Cell Nuclear Antigen | CATH (4.3.0) | |
A [auth D] | 3.70.10.10 | Alpha Beta | Box | Proliferating Cell Nuclear Antigen | CATH (4.3.0) | |
G | 3.70.10.10 | Alpha Beta | Box | Proliferating Cell Nuclear Antigen | CATH (4.3.0) | |
H | 3.70.10.10 | Alpha Beta | Box | Proliferating Cell Nuclear Antigen | CATH (4.3.0) | |
B [auth E] | 3.70.10.10 | Alpha Beta | Box | Proliferating Cell Nuclear Antigen | CATH (4.3.0) | |
E [auth B] | 3.70.10.10 | Alpha Beta | Box | Proliferating Cell Nuclear Antigen | CATH (4.3.0) | |
F [auth C] | 3.70.10.10 | Alpha Beta | Box | Proliferating Cell Nuclear Antigen | CATH (4.3.0) | |
C [auth F] | 3.70.10.10 | Alpha Beta | Box | Proliferating Cell Nuclear Antigen | CATH (4.3.0) | |
I | 3.70.10.10 | Alpha Beta | Box | Proliferating Cell Nuclear Antigen | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A [auth D], D [auth A], G | PF00705 | Proliferating cell nuclear antigen, N-terminal domain (PCNA_N) | Proliferating cell nuclear antigen, N-terminal domain | N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA. | Domain |
B [auth E], E [auth B], H | PF02747 | Proliferating cell nuclear antigen, C-terminal domain (PCNA_C) | Proliferating cell nuclear antigen, C-terminal domain | N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA. | Domain |
B [auth E], E [auth B], H | PF00705 | Proliferating cell nuclear antigen, N-terminal domain (PCNA_N) | Proliferating cell nuclear antigen, N-terminal domain | N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA. | Domain |
C [auth F], F [auth C], I | PF02747 | Proliferating cell nuclear antigen, C-terminal domain (PCNA_C) | Proliferating cell nuclear antigen, C-terminal domain | N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA. | Domain |
C [auth F], F [auth C], I | PF00705 | Proliferating cell nuclear antigen, N-terminal domain (PCNA_N) | Proliferating cell nuclear antigen, N-terminal domain | N-terminal and C-terminal domains of PCNA are topologically identical. Three PCNA molecules are tightly associated to form a closed ring encircling duplex DNA. | Domain |