2PQF

Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APARPe2pqfA1 A: a+b complex topologyX: ADP-ribosylation (From Topology)H: ADP-ribosylation (From Topology)T: ADP-ribosylationF: PARPECOD (1.6)
BPARPe2pqfB1 A: a+b complex topologyX: ADP-ribosylation (From Topology)H: ADP-ribosylation (From Topology)T: ADP-ribosylationF: PARPECOD (1.6)
CPARPe2pqfC1 A: a+b complex topologyX: ADP-ribosylation (From Topology)H: ADP-ribosylation (From Topology)T: ADP-ribosylationF: PARPECOD (1.6)
DPARPe2pqfD1 A: a+b complex topologyX: ADP-ribosylation (From Topology)H: ADP-ribosylation (From Topology)T: ADP-ribosylationF: PARPECOD (1.6)
EPARPe2pqfE1 A: a+b complex topologyX: ADP-ribosylation (From Topology)H: ADP-ribosylation (From Topology)T: ADP-ribosylationF: PARPECOD (1.6)
FPARPe2pqfF1 A: a+b complex topologyX: ADP-ribosylation (From Topology)H: ADP-ribosylation (From Topology)T: ADP-ribosylationF: PARPECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00644Poly(ADP-ribose) polymerase catalytic domain (PARP)Poly(ADP-ribose) polymerase catalytic domain- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR051712Mono-ADP-ribosyltransferase and antiviral proteinFamily
A, B, C, D, E
IPR036388Winged helix-like DNA-binding domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR000571Zinc finger, CCCH-typeDomain
A, B, C, D, E
IPR004170WWE domainDomain
A, B, C, D, E
IPR012317Poly(ADP-ribose) polymerase, catalytic domainDomain
A, B, C, D, E
IPR037197WWE domain superfamilyHomologous Superfamily