2R84
Crystal structure of PurP from Pyrococcus furiosus complexed with AMP and AICAR
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Glutathione synthetase ATP-binding domain-like | 8036655 | 3000094 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | PreATP-grasp domain | 8036653 | 3001680 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Glutathione synthetase ATP-binding domain-like | 8036655 | 3000094 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | PreATP-grasp domain | 8036653 | 3001680 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | DUF1297 | e2r84A1 | A: a+b complex topology | X: Protein kinase/SAICAR synthase/ATP-grasp (From Homology) | H: Protein kinase/SAICAR synthase/ATP-grasp | T: ATP-grasp | F: DUF1297 | ECOD (1.6) |
A | DUF1246 | e2r84A2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: PreATP-grasp domain | F: DUF1246 | ECOD (1.6) |
B | DUF1297 | e2r84B1 | A: a+b complex topology | X: Protein kinase/SAICAR synthase/ATP-grasp (From Homology) | H: Protein kinase/SAICAR synthase/ATP-grasp | T: ATP-grasp | F: DUF1297 | ECOD (1.6) |
B | DUF1246 | e2r84B2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: PreATP-grasp domain | F: DUF1246 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.20 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
A | 3.30.470.20 | Alpha Beta | 2-Layer Sandwich | D-amino Acid Aminotransferase | Chain A, domain 1 | CATH (4.3.0) |
A | 3.30.1490.20 | Alpha Beta | 2-Layer Sandwich | Dna Ligase | domain 1 | CATH (4.3.0) |
B | 3.40.50.20 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | CATH (4.3.0) | |
B | 3.30.470.20 | Alpha Beta | 2-Layer Sandwich | D-amino Acid Aminotransferase | Chain A, domain 1 | CATH (4.3.0) |
B | 3.30.1490.20 | Alpha Beta | 2-Layer Sandwich | Dna Ligase | domain 1 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF06849 | Protein of unknown function (DUF1246) (DUF1246) | Protein of unknown function (DUF1246) | - | Family | |
PF06973 | Domain of unknown function (DUF1297) (DUF1297) | Domain of unknown function (DUF1297) | This family represents the C-terminus (approximately 200 residues) of a number of archaeal proteins of unknown function. One member is annotated as being a possible carboligase enzyme. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR010672 | IMP biosynthesis enzyme PurP, N-terminal | Domain | |
IPR011761 | ATP-grasp fold | Domain | |
IPR016185 | Pre-ATP-grasp domain superfamily | Homologous Superfamily | |
IPR013815 | ATP-grasp fold, subdomain 1 | Homologous Superfamily | |
IPR009720 | IMP biosynthesis enzyme PurP, C-terminal | Domain | |
IPR023656 | IMP biosynthesis enzyme PurP | Family |