Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)
ISCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)
JSCOP2B SuperfamilyWinged helix DNA-binding domain 8085680 3000034 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AGntRe2wv0A2 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
AUTRAe2wv0A1 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)
BGntRe2wv0B1 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
BUTRAe2wv0B2 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)
CGntRe2wv0C1 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
CUTRAe2wv0C2 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)
DGntRe2wv0D1 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
DUTRAe2wv0D2 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)
EGntRe2wv0E1 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
EUTRAe2wv0E2 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)
FGntRe2wv0F1 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
FUTRAe2wv0F2 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)
GGntRe2wv0G1 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
GUTRAe2wv0G2 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)
HGntRe2wv0H4 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
HUTRAe2wv0H3 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)
IGntRe2wv0I1 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
IUTRAe2wv0I2 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)
JGntRe2wv0J1 A: alpha arraysX: HTHH: HTHT: wingedF: GntRECOD (1.6)
JUTRAe2wv0J2 A: a+b two layersX: Chorismate lyase (From Topology)H: Chorismate lyase (From Topology)T: Chorismate lyaseF: UTRAECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
A3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)
B1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
B3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)
C1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
C3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)
D1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
D3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)
E1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
E3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)
F1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
F3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)
G1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
G3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)
H1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
H3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)
I1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
I3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)
J1.10.10.10 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domainCATH (4.3.0)
J3.40.1410.10 Alpha Beta 3-Layer(aba) Sandwich Chorismate lyase Chorismate lyase-likeCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00392Bacterial regulatory proteins, gntR family (GntR)Bacterial regulatory proteins, gntR familyThis family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerisation domain. The GntR-like proteins include the following sub-fam ...This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerisation domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR [1-2][4][5]. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships [3]. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor [5].
Domain
A, B, C, D, E
PF07702UTRA domain (UTRA)UTRA domainThe UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to Pfam:PF04345 [1]. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules ...The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to Pfam:PF04345 [1]. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules [1] sugar phosphates and urocanate, Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
HTH-TYPE TRANSCRIPTIONAL REPRESSOR YVOA -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR050679Bacterial HTH-type transcriptional regulatorFamily
A, B, C, D, E
IPR011663UbiC transcription regulator-associatedDomain
A, B, C, D, E
IPR028978Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR036388Winged helix-like DNA-binding domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR000524Transcription regulator HTH, GntRDomain
A, B, C, D, E
IPR036390Winged helix DNA-binding domain superfamilyHomologous Superfamily