2WZM
Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d2wzma_ | Alpha and beta proteins (a/b) | TIM beta/alpha-barrel | NAD(P)-linked oxidoreductase | automated matches | automated matches | (Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ], | SCOPe (2.08) |
B | d2wzmb_ | Alpha and beta proteins (a/b) | TIM beta/alpha-barrel | NAD(P)-linked oxidoreductase | automated matches | automated matches | (Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2 Family | Aldo-keto reductases (NADP) | 8062048 | 4003124 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | NAD(P)-linked oxidoreductase | 8062049 | 3000288 | SCOP2 (2022-06-29) |
B | SCOP2B Superfamily | NAD(P)-linked oxidoreductase | 8062049 | 3000288 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Aldo_ket_red | e2wzmA1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Aldo_ket_red | ECOD (1.6) |
B | Aldo_ket_red | e2wzmB1 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Aldo_ket_red | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.20.20.100 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | NADP-dependent oxidoreductase domain | CATH (4.3.0) |
B | 3.20.20.100 | Alpha Beta | Alpha-Beta Barrel | TIM Barrel | NADP-dependent oxidoreductase domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00248 | Aldo/keto reductase family (Aldo_ket_red) | Aldo/keto reductase family | This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity [2]. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
ALDO-KETO REDUCTASE | - |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR018170 | Aldo/keto reductase, conserved site | Conserved Site | |
IPR036812 | NADP-dependent oxidoreductase domain superfamily | Homologous Superfamily | |
IPR023210 | NADP-dependent oxidoreductase domain | Domain | |
IPR020471 | Aldo-keto reductase | Family |