2YEQ

Structure of PhoD

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	PhoD-like	8044829	4004162	SCOP2 (2022-06-29)
A	SCOP2 Family	PhoD N-terminal domain-like	8045925	4004767	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Metallo-dependent phosphatases	8053377	3001067	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Purple acid phosphatase N-terminal domain-like	8053378	3002043	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Metallo-dependent phosphatases	8053377	3001067	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Purple acid phosphatase N-terminal domain-like	8053378	3002043	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PhoD_N	e2yeqA2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PhoD_N	ECOD (1.6)
A	PhoD	e2yeqA1	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Metallo-dependent phosphatases (From Topology)	T: Metallo-dependent phosphatases	F: PhoD	ECOD (1.6)
B	PhoD_N	e2yeqB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: PhoD_N	ECOD (1.6)
B	PhoD	e2yeqB2	A: a+b four layers	X: Carbon-nitrogen hydrolase-like	H: Metallo-dependent phosphatases (From Topology)	T: Metallo-dependent phosphatases	F: PhoD	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.40.380	Mainly Beta	Sandwich	Immunoglobulin-like	Purple acid phosphatase-like, N-terminal	CATH (4.3.0)
A	3.60.21.70	Alpha Beta	4-Layer Sandwich	Purple Acid Phosphatase	chain A, domain 2	CATH (4.3.0)
B	2.60.40.380	Mainly Beta	Sandwich	Immunoglobulin-like	Purple acid phosphatase-like, N-terminal	CATH (4.3.0)
B	3.60.21.70	Alpha Beta	4-Layer Sandwich	Purple Acid Phosphatase	chain A, domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF09423	PhoD-like phosphatase (PhoD)	PhoD-like phosphatase	-	Domain
A, B	PF16655	PhoD-like phosphatase, N-terminal domain (PhoD_N)	PhoD-like phosphatase, N-terminal domain	This domain is found at the N-terminus of proteins in the PhoD family Pfam:PF09423.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	ALKALINE PHOSPHATASE D	phosphoric ester hydrolase activity alkaline phosphatase activity hydrolase activity, acting on ester bonds phosphatase activity hydrolase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR032093	Phospholipase D, N-terminal	Domain
A, B	IPR038607	PhoD-like superfamily	Homologous Superfamily
A, B	IPR018946	PhoD-like phosphatase, metallophosphatase domain	Domain
A, B	IPR052900	Phospholipid Metabolizing Enzymes	Family
A, B	IPR029052	Metallo-dependent phosphatase-like	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.