Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad3daya_ Multi-domain proteins (alpha and beta) Acetyl-CoA synthetase-like Acetyl-CoA synthetase-like automated matches automated matches (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AAMP-binding_3rde3dayA1 A: beta barrelsX: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)H: beta-barrel domain in acetyl-CoA synthetase-like proteins (From Topology)T: beta-barrel domain in acetyl-CoA synthetase-like proteinsF: AMP-binding_3rdECOD (1.6)
AAMP-binding_Ce3dayA2 A: a+b two layersX: Alpha-lytic protease prodomain-likeH: a+b domain in acetyl-CoA synthetase-like proteins (From Topology)T: a+b domain in acetyl-CoA synthetase-like proteinsF: AMP-binding_CECOD (1.6)
AAMP-binding_1ste3dayA4 A: a/b three-layered sandwichesX: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)H: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)T: Rossmann-like domain in Acetyl-CoA synthetase-like proteinsF: AMP-binding_1stECOD (1.6)
AAMP-binding_2nde3dayA3 A: a/b three-layered sandwichesX: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)H: Rossmann-like domain in Acetyl-CoA synthetase-like proteins (From Topology)T: Rossmann-like domain in Acetyl-CoA synthetase-like proteinsF: AMP-binding_2ndECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.50.12780 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold ANL, N-terminal domainCATH (4.3.0)
A3.30.300.30 Alpha Beta 2-Layer Sandwich GMP Synthetase Chain A, domain 3CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00501AMP-binding enzyme (AMP-binding)AMP-binding enzyme- Family
PF13193AMP-binding enzyme C-terminal domain (AMP-binding_C)AMP-binding enzyme C-terminal domainThis is a small domain that is found C terminal to Pfam:PF00501. It has a central beta sheet core that is flanked by alpha helices.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
PharosQ08AH3