3DX5

Crystal structure of the probable 3-DHS dehydratase AsbF involved in the petrobactin synthesis from Bacillus anthracis

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	AP_endonuc_2	e3dx5A1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: AP_endonuc_2	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.20.20.150	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Divalent-metal-dependent TIM barrel enzymes	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01261	Xylose isomerase-like TIM barrel (AP_endonuc_2)	Xylose isomerase-like TIM barrel	This TIM alpha/beta barrel structure is found in xylose isomerase (Swiss:P19148) and in endonuclease IV (Swiss:P12638, EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the ...	This TIM alpha/beta barrel structure is found in xylose isomerase (Swiss:P19148) and in endonuclease IV (Swiss:P12638, EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	uncharacterized protein AsbF	3-dehydroshikimate dehydratase activity hydro-lyase activity lyase activity catalytic activity carbon-oxygen lyase activity cation binding ion binding binding metal ion binding small molecule binding	monocarboxylic acid biosynthetic process 3,4-dihydroxybenzoate metabolic process benzene-containing compound metabolic process small molecule biosynthetic process oxoacid metabolic process organic hydroxy compound metabolic process carboxylic acid metabolic process organic acid biosynthetic process organic acid metabolic process catechol-containing compound metabolic process carboxylic acid biosynthetic process biosynthetic process phenol-containing compound metabolic process organic hydroxy compound biosynthetic process 3,4-dihydroxybenzoate biosynthetic process monocarboxylic acid biosynthetic process 3,4-dihydroxybenzoate metabolic process benzene-containing compound metabolic process small molecule biosynthetic process oxoacid metabolic process organic hydroxy compound metabolic process carboxylic acid metabolic process organic acid biosynthetic process organic acid metabolic process catechol-containing compound metabolic process carboxylic acid biosynthetic process biosynthetic process phenol-containing compound metabolic process organic hydroxy compound biosynthetic process 3,4-dihydroxybenzoate biosynthetic process phenol-containing compound biosynthetic process small molecule metabolic process metabolic process cellular process catechol-containing compound biosynthetic process monocarboxylic acid metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR013022	Xylose isomerase-like, TIM barrel domain	Domain
A	IPR036237	Xylose isomerase-like superfamily	Homologous Superfamily
A	IPR050312	IolE/XylA/MocC-like	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.