Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 Familybeta-Lactamase/D-ala carboxypeptidase 8069828 4002685 SCOP2 (2022-06-29)
ASCOP2 Superfamilybeta-lactamase/transpeptidase-like 8069829 3001604 SCOP2 (2022-06-29)
CSCOP2B Superfamilybeta-lactamase/transpeptidase-like 8069829 3001604 SCOP2B (2022-06-29)
BSCOP2 FamilyBLIP-like 8080342 4001739 SCOP2 (2022-06-29)
BSCOP2 SuperfamilyBLIP repeat-like 8092095 3000321 SCOP2 (2022-06-29)
BSCOP2 SuperfamilyBLIP repeat-like 8080343 3000321 SCOP2 (2022-06-29)
DSCOP2B SuperfamilyBLIP repeat-like 8092095 3000321 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyBLIP repeat-like 8080343 3000321 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APeptidase_S11_1st_1e3gmwA3 A: alpha complex topologyX: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: alpha-helical domain in beta-lactamase/transpeptidase-like proteinsF: Peptidase_S11_1st_1ECOD (1.6)
ABeta-lactamase2e3gmwA4 A: a+b three layersX: Profilin-likeH: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: a+b domain in beta-lactamase/transpeptidase-like proteinsF: Beta-lactamase2ECOD (1.6)
CPeptidase_S11_1st_1e3gmwC3 A: alpha complex topologyX: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: alpha-helical domain in beta-lactamase/transpeptidase-like proteinsF: Peptidase_S11_1st_1ECOD (1.6)
CBeta-lactamase2e3gmwC4 A: a+b three layersX: Profilin-likeH: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology)T: a+b domain in beta-lactamase/transpeptidase-like proteinsF: Beta-lactamase2ECOD (1.6)
BBLIPe3gmwB1 A: a+b two layersX: BLIP-likeH: beta-lactamase-inhibitor protein, BLIP (From Topology)T: beta-lactamase-inhibitor protein, BLIPF: BLIPECOD (1.6)
DBLIPe3gmwD1 A: a+b two layersX: BLIP-likeH: beta-lactamase-inhibitor protein, BLIP (From Topology)T: beta-lactamase-inhibitor protein, BLIPF: BLIPECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.710.10 Alpha Beta 3-Layer(aba) Sandwich Beta-lactamase DD-peptidase/beta-lactamase superfamilyCATH (4.3.0)
C3.40.710.10 Alpha Beta 3-Layer(aba) Sandwich Beta-lactamase DD-peptidase/beta-lactamase superfamilyCATH (4.3.0)
B3.10.450.730 Alpha Beta Roll Nuclear Transport Factor 2 Chain: A,CATH (4.3.0)
D3.10.450.730 Alpha Beta Roll Nuclear Transport Factor 2 Chain: A,CATH (4.3.0)

AMR Gene: CARD Annotation CARD Database Homepage

ChainsAccessionShort NameDescriptionProvenance Source (Version)
A, C
ARO:3001044TEM-181TEM-181 is a beta-lactamase.CARD (3.3.0)

AMR Gene Family: CARD Annotation CARD Database Homepage

ChainsAccessionGene FamilyDrug Class Resistance MachanismProvenance Source (Version)
A, C
ARO:3000014TEM beta-lactamasemonobactam, cephalosporin, penam, penemantibiotic inactivationCARD (3.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, C
PF13354Beta-lactamase enzyme family (Beta-lactamase2)Beta-lactamase enzyme familyThis is the catalytic domain of class A beta-lactamases [1]. It is closely related to Beta-lactamase, Pfam:PF00144, the serine beta-lactamase-like superfamily, which contains the distantly related Pfam:PF00905 and PF00768 D-alanyl-D-alanine carboxype ...This is the catalytic domain of class A beta-lactamases [1]. It is closely related to Beta-lactamase, Pfam:PF00144, the serine beta-lactamase-like superfamily, which contains the distantly related Pfam:PF00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
Domain
A, C
PF00144Beta-lactamase (Beta-lactamase)Beta-lactamaseThis family appears to be distantly related to Pfam:PF00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.Domain
B, D
PF07467Beta-lactamase inhibitor (BLIP) (BLIP)Beta-lactamase inhibitor (BLIP)- Family