3GSI
Crystal structure of D552A dimethylglycine oxidase mutant of Arthrobacter globiformis in complex with tetrahydrofolate
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Flavoreductase-like | 8017496 | 3000055 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Folate-binding domain-like | 8001552 | 3000025 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Aminomethyltransferase beta-barrel domain-like | 8056079 | 3000024 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | GCV_T_C | e3gsiA1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: Aminomethyltransferase beta-barrel domain | F: GCV_T_C | ECOD (1.6) |
A | KOG2844 | e3gsiA3 | A: a+b two layers | X: FAD-linked reductases, C-terminal domain-like | H: FAD-linked reductases-C (From Topology) | T: FAD-linked reductases-C | F: KOG2844 | ECOD (1.6) |
A | GCV_T_N | e3gsiA6 | A: a+b two layers | X: Alpha-beta plaits | H: Aminomethyltransferase folate-binding domain (From Topology) | T: Aminomethyltransferase folate-binding domain | F: GCV_T_N | ECOD (1.6) |
A | GCV_T_N1 | e3gsiA5 | A: a+b two layers | X: Alpha-beta plaits | H: Aminomethyltransferase folate-binding domain (From Topology) | T: Aminomethyltransferase folate-binding domain | F: GCV_T_N1 | ECOD (1.6) |
A | DAO_1st | e3gsiA4 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: FAD/NAD(P)-binding domain | F: DAO_1st | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.50.50.60 | Alpha Beta | 3-Layer(bba) Sandwich | FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain | CATH (4.3.0) |
A | 3.30.9.10 | Alpha Beta | 2-Layer Sandwich | D-Amino Acid Oxidase | Chain A, domain 2 | CATH (4.3.0) |
A | 3.30.1360.120 | Alpha Beta | 2-Layer Sandwich | Gyrase A | domain 2 | CATH (4.3.0) |
A | 3.30.70.1400 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | Aminomethyltransferase beta-barrel domains | CATH (4.3.0) |
A | 2.40.30.110 | Mainly Beta | Beta Barrel | Elongation Factor Tu (Ef-tu) | domain 3 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF16350 | FAD dependent oxidoreductase central domain (FAO_M) | FAD dependent oxidoreductase central domain | - | Family | |
PF01571 | Aminomethyltransferase folate-binding domain (GCV_T) | Aminomethyltransferase folate-binding domain | This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyses the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl tran ... | Domain | |
PF01266 | FAD dependent oxidoreductase (DAO) | FAD dependent oxidoreductase | This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1. | Domain | |
PF08669 | Glycine cleavage T-protein C-terminal barrel domain (GCV_T_C) | Glycine cleavage T-protein C-terminal barrel domain | This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyses the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl tran ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
N,N-dimethylglycine oxidase |
| - | - |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR028896 | Aminomethyltransferase-like | Family | |
IPR013977 | Aminomethyltransferase, C-terminal domain | Domain | |
IPR032503 | FAD dependent oxidoreductase, central domain | Domain | |
IPR029043 | Glycine cleavage T-protein/YgfZ, C-terminal | Homologous Superfamily | |
IPR006076 | FAD dependent oxidoreductase | Domain | |
IPR036188 | FAD/NAD(P)-binding domain superfamily | Homologous Superfamily | |
IPR006222 | Aminomethyltransferase, folate-binding domain | Domain | |
IPR027266 | GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 | Homologous Superfamily |