3JUB

Human gamma-glutamylamine cyclotransferase

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Pharos: Disease Associations

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3juba_	Alpha and beta proteins (a+b)	Gamma-glutamyl cyclotransferase-like	Gamma-glutamyl cyclotransferase-like	Gamma-glutamyl cyclotransferase-like	automated matches	human (Homo sapiens ) [TaxId: 9606 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Gamma-glutamyl cyclotransferase-like	8088106	3001318	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	GGACT	e3jubA1	A: a+b two layers	X: BtrG-like (Pfam 03674) (From Topology)	H: BtrG-like (Pfam 03674) (From Topology)	T: BtrG-like (Pfam 03674)	F: GGACT	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.490.10	Alpha Beta	Roll	Hypothetical upf0131 protein ytfp	Gamma-glutamyl cyclotransferase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF06094	Gamma-glutamyl cyclotransferase, AIG2-like (GGACT)	Gamma-glutamyl cyclotransferase, AIG2-like	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	AIG2-like domain-containing protein 1	amidine-lyase activity lyase activity gamma-glutamylaminecyclotransferase activity catalytic activity carbon-nitrogen lyase activity	catabolic process cellular metabolic process metabolic process cellular process cellular modified amino acid metabolic process cellular modified amino acid catabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity cytosol extracellular exosome membrane-bounded organelle extracellular vesicle extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR036568	Gamma-glutamyl cyclotransferase-like superfamily	Homologous Superfamily
A	IPR039126	Gamma-glutamylaminecyclotransferase	Family
A	IPR013024	Gamma-glutamyl cyclotransferase-like	Domain
A	IPR009288	Gamma-glutamylcyclotransferase, AIG2-like domain	Domain

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: Q9BVM4	attention deficit hyperactivity disorder, inattentive type malignant ependymoma medulloblastoma

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.