Annotations: 3JZ0

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	EUF07929	e3jz0A3	A: alpha arrays	X: HhH/H2TH	H: SAM/DNA-glycosylase	T: PAP/OAS1 substrate-binding domain	F: EUF07929	ECOD (1.6)
A	Adenyl_transf_N_1	e3jz0A4	A: a+b three layers	X: Nucleotidyltransferase-like	H: Nucleotidyltransferase (From Topology)	T: Nucleotidyltransferase	F: Adenyl_transf_N_1	ECOD (1.6)
B	EUF07929	e3jz0B3	A: alpha arrays	X: HhH/H2TH	H: SAM/DNA-glycosylase	T: PAP/OAS1 substrate-binding domain	F: EUF07929	ECOD (1.6)
B	Adenyl_transf_N_1	e3jz0B4	A: a+b three layers	X: Nucleotidyltransferase-like	H: Nucleotidyltransferase (From Topology)	T: Nucleotidyltransferase	F: Adenyl_transf_N_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.460.10	Alpha Beta	2-Layer Sandwich	Beta Polymerase	domain 2	CATH (4.3.0)
A	1.20.120.330	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Nucleotidyltransferases domain 2	CATH (4.3.0)
B	3.30.460.10	Alpha Beta	2-Layer Sandwich	Beta Polymerase	domain 2	CATH (4.3.0)
B	1.20.120.330	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Nucleotidyltransferases domain 2	CATH (4.3.0)

AMR Gene: CARD Annotation CARD Database Homepage

Chains	Accession	Short Name	Description	Provenance Source (Version)
A, B	ARO:3002836	lnuB	lnuB is a plasmid-mediated nucleotidyltransferase found in Streptococcus lutetiensis.	CARD (3.3.0)

AMR Gene Family: CARD Annotation CARD Database Homepage

Chains	Accession	Gene Family	Drug Class	Resistance Machanism	Provenance Source (Version)
A, B	ARO:3000221	lincosamide nucleotidyltransferase (LNU)	lincosamide antibiotic	antibiotic inactivation	CARD (3.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF21418	Lincosamide nucleotidyltransferase-like, C-terminal domain (LinB-like_C)	Lincosamide nucleotidyltransferase-like, C-terminal domain	This domain is found at the C-terminal end of Lincosamide nucleotidyltransferase from Enterococcus faecium (LinB) and similar proteins from bacteria. LinB catalyses adenylylation of the lincosamide class of antibiotics. This domain folds into an alph ...	This domain is found at the C-terminal end of Lincosamide nucleotidyltransferase from Enterococcus faecium (LinB) and similar proteins from bacteria. LinB catalyses adenylylation of the lincosamide class of antibiotics. This domain folds into an alpha-helical bundle, which consists of five alpha-helices [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Lincosamide nucleotidyltransferase	cation binding ion binding binding metal ion binding small molecule binding transferase activity catalytic activity identical protein binding protein binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR043519	Nucleotidyltransferase superfamily	Homologous Superfamily
A, B	IPR048495	Lincosamide nucleotidyltransferase-like, C-terminal domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.