Structure of the large fragment of thermus aquaticus DNA polymerase I in complex with a blunt-ended DNA and ddATP
External Resource: Annotation
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
A | SCOP2B Superfamily | Ribonuclease H-like | 8044539 | 3000143 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Nucleotide cyclase/DNA polymerase palm domain-like | 8037492 | 3001272 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Nucleotide cyclase/DNA polymerase palm domain-like | 8037492 | 3001272 | SCOP2B (2022-06-29) |
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
A | DNA_pol_A_2nd | e3lwmA1 | A: alpha arrays | X: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology) | H: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology) | T: helical bundle in Bacillus stearothermophilus-like DNA polymerase I | F: DNA_pol_A_2nd | ECOD (1.6) |
A | DNA_pol_A_1st | e3lwmA2 | A: alpha bundles | X: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology) | H: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology) | T: fingers domain in bacteriophage RB69-like DNA polymerase I | F: DNA_pol_A_1st | ECOD (1.6) |
A | DNA_pol_A_3rd | e3lwmA3 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: DNA_pol_A_3rd | ECOD (1.6) |
A | Taq-exonuc | e3lwmA4 | A: mixed a+b and a/b | X: Ribonuclease H-like | H: Ribonuclease H-like (From Topology) | T: Ribonuclease H-like | F: Taq-exonuc | ECOD (1.6) |
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|
| DNA polymerase I, thermostable | | | - |
| DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3') | - | - | - |
| DNA (5'-D(*TP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3') | - | - | - |
Chains | Accession | Name | Type |
---|
| IPR036397 | Ribonuclease H superfamily | Homologous Superfamily |
| IPR002421 | 5'-3' exonuclease | Domain |
| IPR043502 | DNA/RNA polymerase superfamily | Homologous Superfamily |
| IPR020045 | DNA polymerase I-like, H3TH domain | Domain |
| IPR015361 | Taq polymerase, thermostable, exonuclease region | Domain |
| IPR001098 | DNA-directed DNA polymerase, family A, palm domain | Domain |
| IPR029060 | PIN-like domain superfamily | Homologous Superfamily |
| IPR036279 | 5'-3' exonuclease, C-terminal domain superfamily | Homologous Superfamily |
| IPR008918 | Helix-hairpin-helix motif, class 2 | Conserved Site |
| IPR002298 | DNA polymerase A | Family |
| IPR020046 | 5'-3' exonuclease, alpha-helical arch, N-terminal | Domain |
| IPR019760 | DNA-directed DNA polymerase, family A, conserved site | Conserved Site |
| IPR018320 | DNA polymerase 1 | Family |
| IPR003583 | Helix-hairpin-helix DNA-binding motif, class 1 | Domain |
| IPR012337 | Ribonuclease H-like superfamily | Homologous Superfamily |