3MCN

Crystal Structure of the 6-hyroxymethyl-7,8-dihydropterin pyrophosphokinase dihydropteroate synthase bifunctional enzyme from Francisella tularensis

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
BHPPKe3mcnB2 A: a+b two layersX: Alpha-beta plaitsH: 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK (From Topology)T: 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKF: HPPKECOD (1.6)
BPterin_binde3mcnB1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Pterin_bindECOD (1.6)
AHPPKe3mcnA1 A: a+b two layersX: Alpha-beta plaitsH: 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK (From Topology)T: 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPKF: HPPKECOD (1.6)
APterin_binde3mcnA4 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Pterin_bindECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
B3.30.70.560 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPKCATH (4.3.0)
B3.20.20.20 Alpha Beta Alpha-Beta Barrel TIM Barrel Dihydropteroate synthase-likeCATH (4.3.0)
A3.30.70.560 Alpha Beta 2-Layer Sandwich Alpha-Beta Plaits 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPKCATH (4.3.0)
A3.20.20.20 Alpha Beta Alpha-Beta Barrel TIM Barrel Dihydropteroate synthase-likeCATH (4.3.0)